Nfkbid Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Nfkbid
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
MGI:3041243

26 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Nfkbid^m1Btlr/Nfkbid^m1Btlr involves: C57BL/6J	abnormal class switch recombination	J:185495
	absent marginal zone B cells	J:185495
	decreased B cell proliferation	J:185495
	decreased B-1 B cell number	J:185495
	decreased B-1a cell number	J:185495
	decreased IgG1 level	J:185495
	decreased IgG3 level	J:185495
	decreased IgG level	J:185495
	decreased IgM level	J:185495
	normal immune system phenotype	J:185495
	increased B cell apoptosis	J:185495
Nfkbid^{tm1a(EUCOMM)Wtsi}/Nfkbid⁺ C57BL/6N-Nfkbid^{tm1a(EUCOMM)Wtsi}/Cnrm	abnormal behavior	J:165965
	decreased B cell number	J:165965
	decreased circulating free fatty acids level	J:165965
	decreased circulating triglyceride level	J:165965
Nfkbid^{tm1a(EUCOMM)Wtsi}/Nfkbid^{tm1a(EUCOMM)Wtsi} involves: C57BL/6N	abnormal class switch recombination	J:185495
	decreased IgG level	J:185495
	decreased IgM level	J:185495
Nfkbid^tm1Clay/Nfkbid^tm1Clay involves: 129S6/SvEvTac * C57BL/6	abnormal NK cell physiology	J:132071
	abnormal thymocyte activation	J:132071
	decreased interferon-gamma secretion	J:132071
	decreased interleukin-2 secretion	J:132071
	decreased T cell proliferation	J:132071
Nfkbid^tm1Ktak/Nfkbid^tm1Ktak involves: 129P2/OlaHsd * C57BL/6	increased interferon-gamma secretion	J:113334
	increased interleukin-6 secretion	J:113334
	increased interleukin-12 secretion	J:113334
	increased interleukin-12b secretion	J:113334
	increased susceptibility to endotoxin shock	J:113334
	increased susceptibility to induced colitis	J:113334

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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