Gsdma3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Gsdma3
gasdermin A3
MGI:3044668

53 phenotypes from 11 alleles in 11 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Gsdma3^Ae/Gsdma3⁺ involves: C57BL/6J * CAST/Ei	abnormal coat appearance	J:180149
	abnormal hair cuticle	J:166522
	abnormal hair cycle	J:180149
	abnormal hair cycle catagen phase	J:180149
	abnormal hair follicle bulge morphology	J:180149
	abnormal skin adnexa morphology	J:180149
	abnormal skin morphology	J:180149
	abnormal skin physiology	J:180149
	cornea opacity	J:180149
	delayed hair regrowth	J:180149
	enlarged lymph nodes	J:180149
	enlarged spleen	J:180149
	enlarged thymus	J:180149
	epidermal hyperplasia	J:180149
	progressive hair loss	J:180149
	skin inflammation	J:180149
	thin hair shaft	J:166522
	wrinkled skin	J:180149
Gsdma3^Ae/Gsdma3^Ae involves: C57BL/6J * CAST/Ei	abnormal coat appearance	J:180149
	abnormal skin physiology	J:180149
	cornea opacity	J:180149
	progressive hair loss	J:180149
	wrinkled skin	J:180149
Gsdma3^Bsk/Gsdma3⁺ Not Specified	alopecia	J:18276
	cornea opacity	J:18276
	sparse hair	J:18276
	thick skin	J:18276
	wrinkled skin	J:18276
Gsdma3^Bsk/Gsdma3^Bsk Not Specified	alopecia	J:18276
	cornea opacity	J:18276
	normal reproductive system phenotype	J:18276
	sparse hair	J:18276
	thick skin	J:18276
	wrinkled skin	J:18276
Gsdma3^Dfl/Gsdma3⁺ involves: BALB/c	abnormal guard hair morphology	J:78078
	alopecia	J:78078
	cornea opacity	J:78078
	thick skin	J:78078
	wrinkled skin	J:78078
Gsdma3^Fgn/Gsdma3⁺ involves: BALB/c * C3H/HeH	abnormal hair cycle	J:83412
Gsdma3^Fgn/Gsdma3⁺ involves: BALB/c * C3H/HeH	alopecia	J:83412
Gsdma3^M1Btlr/Gsdma3⁺ either: C57BL/6J-Gsdma3^M1Btlr or (involves: C3H * C57BL/6J)	big ears	J:146738
	coarse hair	J:146738
	long hair	J:146738
	microphthalmia	J:146738
	progressive hair loss	J:146738
	wrinkled skin	J:146738
Gsdma3^M1Btlr/Gsdma3^M1Btlr either: C57BL/6J-Gsdma3^M1Btlr or (involves: C3H * C57BL/6J)	big ears	J:146738
	coarse hair	J:146738
	cornea opacity	J:146738
	long hair	J:146738
	microphthalmia	J:146738
	progressive hair loss	J:146738
	wrinkled skin	J:146738
Gsdma3^M2Btlr/Gsdma3^M2Btlr involves: C57BL/6J	dermatitis	J:209203
	dry skin	J:209203
	eye opacity	J:209203
	progressive hair loss	J:209203
	skin lesions	J:209203
Gsdma3^Mhdaclp1/Gsdma3⁺ C3HeB/FeJ-Gsdma3^Mhdaclp1	absent sebaceous gland	J:220424
	alopecia	J:220424
	decreased alkaline phosphatase activity	J:220424
Gsdma3^Mhdaclp1/Gsdma3^Mhdaclp1 C3HeB/FeJ-Gsdma3^Mhdaclp1	alopecia	J:220424
Gsdma3^Mhdaclp1/Gsdma3^Mhdaclp1 C3HeB/FeJ-Gsdma3^Mhdaclp1	decreased alkaline phosphatase activity	J:220424
Gsdma3^Rco2/Gsdma3⁺ C3HeB/FeJ-Gsdma3^Rco2	abnormal coat appearance	J:93938
	abnormal hair follicle development	J:93938
	abnormal hair growth	J:93938
	abnormal skin condition	J:93938
	normal integument phenotype	J:93938
Gsdma3^Re-Den/Gsdma3^Re-Den involves: C3HeB/FeJ	abnormal coat appearance	J:93938
Gsdma3^Rim3/Gsdma3⁺ involves: C57BL/10J * DBA/2J	abnormal cornea epithelium morphology	J:42692
	abnormal cornea stroma development	J:42692
	abnormal epidermal layer morphology	J:42692
	abnormal hair cycle	J:122738
	abnormal hair cycle anagen phase	J:122738
	abnormal hair growth	J:42692
	acanthosis	J:42692
	cornea opacity	J:42692
	decreased hair follicle number	J:42692
	hypergranulosis	J:42692
	hyperkeratosis	J:42692
	sparse hair	J:42692
	thick epidermis	J:42692
Gsdma3^Rim3/Gsdma3^Rim3 involves: C57BL/10J * DBA/2J	abnormal cornea stroma development	J:42692
	abnormal epidermal layer morphology	J:42692
	acanthosis	J:42692
	cornea opacity	J:42692
	decreased hair follicle number	J:42692
	disorganized cornea epithelium	J:42692
	hypergranulosis	J:42692
	hyperkeratosis	J:42692
	increased cornea stroma thickness	J:42692
	thick epidermis	J:42692
Gsdma3^{tm1(KOMP)Vlcg}/Gsdma3^{tm1(KOMP)Vlcg} C57BL/6N-Gsdma3^{tm1(KOMP)Vlcg}/Nju	decreased erythrocyte cell number	J:211773
	decreased hematocrit	J:211773
	increased lymphocyte cell number	J:211773
	increased mean corpuscular hemoglobin	J:211773
	increased mean corpuscular hemoglobin concentration	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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