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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Scube3
signal peptide, CUB domain, EGF-like 3
MGI:3045253
69 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Scube3m1Btlr/Scube3m1Btlr
C57BL/6J-Scube3m1Btlr 		abnormal vertebral column morphology J:307652
kinked tail J:307652
kyphosis J:307652
Scube3m1Mhda/Scube3m1Mhda
C3HeB/FeJ-Scube3m1Mhda 		abnormal anxiety-related response J:237904
abnormal body composition J:237904
abnormal bone ossification J:237904
abnormal digit morphology J:237904
abnormal enzyme/coenzyme activity J:237904
abnormal food intake J:237904
abnormal inner ear morphology J:237904
abnormal interventricular septum morphology J:237904
abnormal lumbar vertebrae morphology J:237904
abnormal malleus head morphology J:237904
abnormal malleus morphology J:237904
abnormal metacarpal bone morphology J:237904
abnormal metatarsal bone morphology J:237904
abnormal middle ear morphology J:237904
abnormal middle ear ossicle morphology J:237904
abnormal pectoral girdle bone morphology J:237904
abnormal posture J:237904
abnormal renal filtration J:237904
abnormal tarsal bone morphology J:237904
abnormal temporal bone morphology J:237904
abnormal thoracic vertebrae morphology J:237904
abnormal vertebral pedicle morphology J:237904
conductive hearing loss J:237904
decreased body fat mass J:237904
decreased body size J:237904
decreased bone mineral content J:237904
decreased bone mineral density J:237904
decreased circulating cholesterol level J:237904
decreased circulating free fatty acids level J:237904
decreased circulating glucose level J:237904
decreased circulating glycerol level J:237904
decreased circulating phosphate level J:237904
decreased circulating serum albumin level J:237904
decreased circulating total protein level J:237904
decreased circulating triglyceride level J:237904
decreased grip strength J:237904
decreased heart left ventricle posterior wall thickness J:237904
decreased heart left ventricle weight J:237904
decreased lean body mass J:237904
decreased locomotor activity J:237904
decreased pulmonary respiratory rate J:237904
decreased urine albumin level J:237904
decreased urine creatinine level J:237904
decreased urine glucose level J:237904
decreased urine protein level J:237904
decreased urine uric acid level J:237904
decreased vertical activity J:237904
fused phalanges J:237904
improved glucose tolerance J:237904
increased alkaline phosphatase activity J:237904
increased blood urea nitrogen level J:237904
increased blood uric acid level J:237904
increased bone resorption J:237904
increased circulating calcium level J:237904
increased circulating creatinine level J:237904
increased circulating potassium level J:237904
increased fluid intake J:237904
increased or absent threshold for auditory brainstem response J:237904
kinked tail J:237904
polyuria J:237904
prolonged QRS complex duration J:237904
rib fusion J:237904
short femur J:237904
short tail J:237904
small incus J:237904
small middle ear ossicles J:237904
Scube3tm1(KOMP)Vlcg/Scube3tm1(KOMP)Vlcg
involves: C57BL/6NTac 		no abnormal phenotype detected J:195784
Scube3tm1Dgen/Scube3tm1Dgen
involves: 129P2/OlaHsd * C57BL/6 		no abnormal phenotype detected J:168645
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory