Fan1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Fan1
FANCD2/FANCI-associated nuclease 1
MGI:3045266

5 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Fan1^em1Mem/Fan1^em1Mem Htt^tm5Mem/Htt⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal cell physiology	J:298297
	increased cellular sensitivity to alkylating agents	J:298297
Fan1^em1Mem/Fan1^em1Mem Htt^tm5Mem/Htt⁺ Mlh1^tm1Rak/Mlh1^tm1Rak involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J	normal cellular phenotype	J:298297
Fan1^em2Mem/Fan1⁺ Htt^tm3Mem/Htt⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal cell physiology	J:298297
Fan1^em2Mem/Fan1^em2Mem Htt^tm3Mem/Htt⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal cell physiology	J:298297
Fan1^em2Mem/Fan1^em2Mem Htt^tm5Mem/Htt⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal cell physiology	J:298297
Fan1^tm1.1Jrou/Fan1^tm1.1Jrou Fancd2^{Gt(OST57859)Lex}/Fancd2^{Gt(OST57859)Lex} involves: 129P2/OlaHsd * 129S5/SvEvBrd	increased physiological sensitivity to xenobiotic	J:232403
Fan1^tm1.1Jrou/Fan1^tm1.1Jrou Slx1b^tm1.1Jrou/Slx1b^tm1.1Jrou involves: 129P2/OlaHsd	increased physiological sensitivity to xenobiotic	J:232403
Fan1^tm1.1Jrou/Fan1^tm1.1Jrou Slx4^tm1.2Jrou/Slx4^tm1.2Jrou involves: 129P2/OlaHsd	increased physiological sensitivity to xenobiotic	J:232403
Fan1^{tm1d(KOMP)Wtsi}/Fan1^{tm1d(KOMP)Wtsi} Fancd2^tm1Hou/Fancd2^tm1Hou involves: 129S4/SvJae * C57BL/6N * FVB/N	abnormal hematopoietic stem cell morphology	J:232402
	increased physiological sensitivity to xenobiotic	J:232402
Fan1^{tm1d(KOMP)Wtsi}/Fan1^{tm1d(KOMP)Wtsi} Mus81^tm1Chmg/Mus81^tm1Chmg involves: 129S5/SvEvBrd * C57BL/6N * FVB/N	increased physiological sensitivity to xenobiotic	J:232402

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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