Zc3h12d Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Zc3h12d
zinc finger CCCH type containing 12D
MGI:3045313

10 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Zc3h12d^{tm1b(EUCOMM)Hmgu}/Zc3h12d^{tm1b(EUCOMM)Hmgu} C57BL/6N-Zc3h12d^{tm1b(EUCOMM)Hmgu}/Orl	decreased lymphocyte cell number	J:211773
	increased circulating alanine transaminase level	J:211773
	increased monocyte cell number	J:211773
	increased neutrophil cell number	J:211773
Zc3h12d^tm1Tom/Zc3h12d^tm1Tom B6.Cg-Zc3h12d^tm1Tom	normal immune system phenotype	J:209383
	increased interleukin-6 secretion	J:209383
	increased interleukin-10 secretion	J:209383
	increased susceptibility to experimental autoimmune encephalomyelitis	J:209383
	increased T cell proliferation	J:209383
	increased T-helper 17 cell number	J:209383

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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