Akap6 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Akap6
A kinase anchor protein 6
MGI:3050566

14 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Akap6^tm1.1Mskf/Akap6^tm1.1Mskf A1cf^{Tg(Myh6-cre/Esr1)1Jmk}/A1cf⁺ involves: C57BL/6 FVB/N * SJL	abnormal heart ventricles weight	J:214288
	cardiac interstitial fibrosis	J:214288
	decreased heart rate	J:214288
	heart left ventricle hypertrophy	J:214288
	increased cardiomyocyte apoptosis	J:214288
	increased heart left atrium weight	J:214288
	increased heart left ventricle wall thickness	J:214288
	increased heart left ventricle weight	J:214288
	increased myocardial fiber size	J:214288
Akap6^tm1.1Mskf/Akap6^tm1.1Mskf Nkx2-5^tm1(cre)Rjs/0 involves: 129S7/SvEvBrd * C57BL/6 * SJL	no abnormal phenotype detected	J:214288
Akap6^tm1.2Mskf/Akap6^tm1.2Mskf involves: BALB/cJ * C57BL/6 * SJL	neonatal lethality	J:214288
Akap6^tm1Jsco/Akap6^tm1Jsco involves: 129 * Black Swiss	abnormal craniofacial morphology	J:121227
	decreased body weight	J:121227
	postnatal lethality, incomplete penetrance	J:121227

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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