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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mrtfb
myocardin related transcription factor B
MGI:3050795
19 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Mrtfatm1Eno/Mrtfatm1Eno
Mrtfbtm2.1Eno/Mrtfbtm2.1Eno
Tg(GFAP-cre)25Mes/0
involves: 129 * 129S/SvEv * C57BL/6 * FVB/N 		abnormal dentate gyrus morphology J:161853
abnormal hippocampus morphology J:161853
abnormal hippocampus neuron morphology J:161853
abnormal hippocampus pyramidal cell layer J:161853
abnormal neuron differentiation J:161853
abnormal neuronal migration J:161853
abnormal olfactory bulb morphology J:161853
abnormal postnatal subventricular zone morphology J:161853
abnormal rostral migratory stream morphology J:161853
absent anterior commissure J:161853
absent corpus callosum J:161853
decreased body weight J:161853
decreased striatum size J:161853
impaired fibroblast cell migration J:161853
increased neuron apoptosis J:161853
postnatal lethality, complete penetrance J:161853
Mrtfbem1Dsr/Mrtfb+
Myh7em1Dsr/Myh7+
involves: C57BL/6J 		abnormal trabecula carnea morphology J:277399
Mrtfbem1Dsr/Mrtfb+
Myh7em1Dsr/Myh7+
Nkx2-5em1Dsr/Nkx2-5+
involves: C57BL/6J 		abnormal trabecula carnea morphology J:277399
increased response of heart to induced stress J:277399
thin ventricular wall J:277399
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory