Unc13a Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Unc13a
unc-13 homolog A
MGI:3051532

10 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Stx1b^tm1.1Sud/Stx1b^tm1.1Sud Unc13a^tm1Bros/Unc13a^tm1Bros involves: 129S1/Sv * 129X1/SvJ * C57BL/6	postnatal lethality	J:138035
Unc13a^tm1Bros/Unc13a^tm1Bros Unc13b^tm2Bros/Unc13b^tm2Bros involves: 129	abnormal excitatory postsynaptic currents	J:167753
	abnormal neuron physiology	J:167753
	abnormal synapse morphology	J:77339
	abnormal synaptic transmission	J:77339
	abnormal synaptic vesicle number	J:77339
	neonatal lethality, complete penetrance	J:77339
Unc13a^tm2Bros/Unc13a⁺ Unc13b^tm2Bros/Unc13b^tm2Bros Not Specified	abnormal excitatory postsynaptic currents	J:117827
	abnormal synaptic vesicle morphology	J:117827
	abnormal synaptic vesicle number	J:117827
Unc13a^tm2Bros/Unc13a^tm2Bros Unc13b^tm2Bros/Unc13b^tm2Bros Not Specified	abnormal excitatory postsynaptic currents	J:117827
	abnormal long-term depression	J:117827
	abnormal miniature excitatory postsynaptic currents	J:117827
	abnormal synaptic vesicle morphology	J:117827
	abnormal synaptic vesicle number	J:117827

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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