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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ppp1r13l
protein phosphatase 1, regulatory subunit 13 like
MGI:3525053
59 phenotypes from 5 alleles in 6 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Gt(ROSA)26Sortm1(cre/ERT)Brn/Gt(ROSA)26Sor+
Ppp1r13ltm1Xlu/Ppp1r13ltm1Xlu
involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6J 		abnormal cell cycle J:177360
abnormal keratinocyte differentiation J:177360
decreased fibroblast proliferation J:177360
early cellular replicative senescence J:177360
Ppp1r13ltm1.1Xlu/Ppp1r13l+
involves: 129 * BALB/cJ * C57BL/6J 		decreased fibroblast proliferation J:177360
Ppp1r13ltm1.1Xlu/Ppp1r13l+
involves: 129 * C57BL/6J 		premature death J:220162
Ppp1r13ltm1.1Xlu/Ppp1r13ltm1.1Xlu
involves: 129 * BALB/cJ * C57BL/6J 		abnormal cell morphology J:177360
abnormal epidermal layer morphology J:177360
decreased fibroblast proliferation J:177360
decreased keratinocyte proliferation J:177360
early cellular replicative senescence J:177360
epidermal hyperplasia J:177360
thick epidermis J:177360
Ppp1r13ltm1.1Xlu/Ppp1r13ltm1.1Xlu
involves: 129 * C57BL/6J 		abnormal cardiac thrombosis J:220162
abnormal heart echocardiography feature J:220162
abnormal heart morphology J:220162
abnormal intercalated disk morphology J:220162
abnormal myocardial fiber morphology J:220162
abnormal myocardium layer morphology J:220162
cardiac fibrosis J:220162
cardiac muscle degeneration J:220162
decreased cardiac output J:220162
decreased cardiac stroke volume J:220162
decreased heart right ventricle wall thickness J:220162
decreased heart ventricle muscle contractility J:220162
dilated heart right ventricle J:220162
dilated heart ventricle J:220162
disorganized myocardium J:220162
premature death J:220162
ventricular cardiomyopathy J:220162
ventricular premature beat J:220162
ventricular tachycardia J:220162
Ppp1r13lwa3-J/Ppp1r13lwa3-J
BALB/cJ-Ppp1r13lwa3-J/J 		blindness J:264272
cardiomyopathy J:146206
congestive heart failure J:146206
dilated cardiomyopathy J:264272
eyelids open at birth J:146206, J:264272
female infertility J:146206
heart inflammation J:264272
reduced male fertility J:146206
sparse hair J:146206, J:264272
waved hair J:264272
Ppp1r13lwa3/Ppp1r13lwa3
either: C57BL/6-Ppp1r13lwa3 or (involves: C57BL/6 * DBA/2J) 		abnormal arterial thrombosis J:96392
decreased body weight J:96392
decreased cardiac muscle contractility J:96392
dilated cardiomyopathy J:96392
dilated heart right ventricle J:96392
eyelids open at birth J:96392
myocardium necrosis J:96392
postnatal lethality, incomplete penetrance J:96392
pregnancy-related premature death J:96392
thin hair shaft J:96392
waved hair J:96392
Ppp1r13lwoe2/Ppp1r13lwoe2
involves: 129X1/SvJ * C57BL/6 		abnormal conjunctival sac morphology J:190557
abnormal cornea morphology J:190557
abnormal eyelid morphology J:190557
abnormal heart morphology J:190557
abnormal interventricular septum morphology J:190557
abnormal iris morphology J:190557
abnormal myocardium layer morphology J:190557
abnormal retina morphology J:190557
absent Meibomian glands J:190557
anterior iris synechia J:190557
aphakia J:190557
cornea opacity J:190557
cornea vascularization J:190557
eyelids open at birth J:190557
failure of eyelid fusion J:190557
hyperkeratosis J:190557
microphthalmia J:190557
premature death J:190557
waved hair J:190557
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory