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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ano5
anoctamin 5
MGI:3576659
50 phenotypes from 4 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ano5em1Huyi/Ano5+
C57BL/6N-Ano5em1Huyi 		abnormal osteoblast physiology J:294237
abnormal skeleton morphology J:294237
increased circulating alkaline phosphatase level J:294237
Ano5em1Huyi/Ano5em1Huyi
C57BL/6N-Ano5em1Huyi 		abnormal dentin morphology J:294237
abnormal long bone diaphysis morphology J:294237
abnormal osteoblast physiology J:294237
abnormal periodontal ligament morphology J:294237
abnormal skeletal muscle morphology J:294237
abnormal tibia morphology J:294237
abnormal trabecular bone morphology J:294237
bowed tibia J:294237
decreased bone trabecula number J:294237
decreased bone volume J:294237
decreased trabecular bone thickness J:294237
increased angiogenesis J:294237
increased bone mineral content J:294237
increased bone mineral density J:294237
increased bone trabecular spacing J:294237
increased circulating alkaline phosphatase level J:294237
increased circulating creatine kinase level J:294237
increased compact bone thickness J:294237
large mandible J:294237
mandibular hyperostosis J:294237
osteosclerosis J:294237
periodontium inflammation J:294237
reduced male fertility J:294237
Ano5em2Huyi/Ano5em2Huyi
C57BL/6-Ano5em2Huyi 		abnormal bone collagen fibril morphology J:336715
abnormal mandible morphology J:336715
abnormal osteoclast physiology J:336715
bowed tibia J:336715
decreased bone strength J:336715
decreased bone trabecula number J:336715
decreased osteoclast cell number J:336715
decreased trabecular bone thickness J:336715
enhanced osteoblast differentiation J:336715
increased bone mineral content J:336715
increased bone mineral density J:336715
increased bone ossification J:336715
increased bone trabecular spacing J:336715
increased circulating alkaline phosphatase level J:336715
increased compact bone thickness J:336715
increased trabecular bone connectivity density J:336715
large mandible J:336715
osteomyelitis J:336715
osteosclerosis J:336715
reduced fertility J:336715
Ano5tm1.2Naga/Ano5tm1.2Naga
involves: C57BL/6 		normal behavior/neurological phenotype J:236134
decreased activated sperm motility J:236134
decreased sperm progressive motility J:236134
normal homeostasis/metabolism phenotype J:236134
normal muscle phenotype J:236134
reduced male fertility J:236134
normal reproductive system phenotype J:236134
Ano5tm1Lrk/Ano5tm1Lrk
involves: C57BL/6 		abnormal diaphragm morphology J:235810
abnormal gastrocnemius morphology J:235810
abnormal mitochondrial physiology J:235810
abnormal skeletal muscle fiber mitochondrial morphology J:235810
abnormal skeletal muscle morphology J:235810
abnormal tibialis anterior morphology J:235810
centrally nucleated skeletal muscle fibers J:235810
delayed skeletal muscle regeneration J:235810
impaired skeletal muscle regeneration J:235810
increased circulating creatine kinase level J:235810
increased muscle fatigability J:235810
normal muscle phenotype J:235810
skeletal muscle fiber necrosis J:235810
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory