Mfsd2b Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mfsd2b
MFSD2 lysolipid transporter B, sphingolipid
MGI:3583946

18 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mfsd2b^{tm1a(KOMP)Wtsi}/Mfsd2b^{tm1a(KOMP)Wtsi} B6JTyr;B6N-Mfsd2b^{tm1a(KOMP)Wtsi}/Wtsi	decreased circulating iron level	J:175295
	decreased erythrocyte cell number	J:175295
	increased mean corpuscular hemoglobin	J:175295
Mfsd2b^{tm1a(KOMP)Wtsi}/Mfsd2b^{tm1a(KOMP)Wtsi} C57BL/6-Mfsd2b^{tm1a(KOMP)Wtsi}	abnormal ceramide level	J:250123
	abnormal mean corpuscular volume	J:250123
	abnormal stress erythropoiesis	J:250123
	decreased B cell number	J:250123
	decreased erythrocyte cell number	J:250123
	decreased leukocyte cell number	J:250123
	decreased sphingosine level	J:250123
	decreased T cell number	J:250123
	enlarged spleen	J:250123
	normal hematopoietic system phenotype	J:250123
	hemolysis	J:250123
	normal homeostasis/metabolism phenotype	J:250123
	increased sphingosine level	J:250123
	increased susceptibility to type I hypersensitivity reaction	J:250123
	reticulocytopenia	J:250123
	stomatocytosis	J:250123

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24