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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Lin28b
lin-28 homolog B
MGI:3584032
12 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Lin28atm1.1Gqda/Lin28a+
Lin28btm1.1Gqda/Lin28btm1.1Gqda
involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N 		decreased body size J:199720
Lin28atm1.1Gqda/Lin28atm1.1Gqda
Lin28btm1.1Gqda/Lin28btm1.1Gqda
involves: 129S4/SvJae * BALB/c * C57BL/6 * FVB/N 		abnormal forebrain development J:199720
collapsed brain ventricles J:199720
decreased embryo size J:199720
embryonic growth retardation J:199720
embryonic lethality during organogenesis, complete penetrance J:199720
open neural tube J:199720
Lin28atm2.1Gqda/Lin28atm2.1Gqda
Lin28btm2.1Gqda/Lin28btm2.1Gqda
STOCK Lin28atm2.1Gqda Lin28btm2.1Gqda/J 		no abnormal phenotype detected J:101977
Lin28btm1.1Gqda/Lin28btm1.1Gqda
Tsc1tm1.1Djk/Tsc1+
involves: 129S4/SvJae * C57BL/6 * FVB 		normal growth/size/body region phenotype J:199720
Lin28btm1Gqda/Lin28btm1Gqda
Myf5tm1(cre)Mrc/Myf5+
Tsc1tm1Djk/Tsc1+
involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 		normal growth/size/body region phenotype J:199720
Mirc31tm1.1Aru/Mirc31tm1.1Aru
Tg(Vil1-cre)997Gum/0
Tg(Vil1-Lin28b,-tdTomato)LoAru/0
involves: 129S4/SvJae * C57BL/6 * C57BL/6J * SJL 		abnormal crypts of Lieberkuhn morphology J:202923
decreased Paneth cell number J:202923
Tg(tetO-Mirlet7a/Mir155,Vil1-rtTA)#Aru/0
Tg(Vil1-Lin28b,-tdTomato)MedAru/0
involves: C57BL/6J * SJL 		normal digestive/alimentary phenotype J:202923
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory