Stac3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Stac3
SH3 and cysteine rich domain 3
MGI:3606571

39 phenotypes from 1 allele in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Stac3^{tm1a(KOMP)Wtsi}/Stac3^{tm1a(KOMP)Wtsi} B6(Cg)-Stac3^{tm1a(KOMP)Wtsi}	abnormal extensor digitorum longus morphology	J:200631
	abnormal limb posture	J:200631
	abnormal posture	J:200631
	abnormal skeletal muscle fiber morphology	J:200631
	abnormal Z line morphology	J:200631
	normal cardiovascular system phenotype	J:200631
	centrally nucleated skeletal muscle fibers	J:200631
	decreased fetal weight	J:200631
	decreased skeletal muscle fiber number	J:200631
	increased skeletal muscle fiber diameter	J:200631
	neonatal lethality, complete penetrance	J:200631
	no spontaneous movement	J:200631
	thin diaphragm muscle	J:200631
	unresponsive to tactile stimuli	J:200631
Stac3^{tm1a(KOMP)Wtsi}/Stac3^{tm1a(KOMP)Wtsi} involves: C57BL/6N	abnormal calcium ion homeostasis	J:222015
	abnormal costal cartilage morphology	J:222015
	abnormal deltoid tuberosity morphology	J:222015
	abnormal diaphragm morphology	J:222015
	abnormal miniature endplate potential	J:222015
	abnormal muscle electrophysiology	J:222015
	abnormal neuromuscular synapse morphology	J:222015
	abnormal phrenic nerve innervation pattern to diaphragm	J:222015
	abnormal postnatal growth/weight/body size	J:222015
	abnormal rib morphology	J:222015
	abnormal sarcomere morphology	J:222015
	abnormal skeletal muscle fiber morphology	J:222015
	abnormal skeletal muscle morphology	J:222015
	abnormal skeleton development	J:222015
	abnormal spine curvature	J:222015
	abnormal sternum morphology	J:222015
	abnormal tongue muscle morphology	J:222015
	abnormal trochanter morphology	J:222015
	carpoptosis	J:222015
	centrally nucleated skeletal muscle fibers	J:222015
	decreased skeletal muscle mass	J:222015
	hypoxia	J:222015
	impaired skeletal muscle contractility	J:222015
	kyphosis	J:222015
	limp posture	J:222015
	neonatal lethality, complete penetrance	J:222015
	paralysis	J:222015
	primary atelectasis	J:222015
	thin diaphragm muscle	J:222015

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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