Del(1)1Brk Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Del(1)1Brk
deletion, Chr 1, Jane Barker 1
MGI:3608907

49 phenotypes from 1 allele in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Del(1)1Brk/Del(1)1Brk B6.CBA-Del(1)1Brk	anemia	J:100202
	decreased birth body size	J:100202
	hydrocephaly	J:100202
	male infertility	J:100202
	pallor	J:100202
	postnatal lethality, incomplete penetrance	J:100202
	prenatal lethality, incomplete penetrance	J:100202
	sparse hair	J:100202
Del(1)1Brk/Del(1)1Brk CBA/J-Del(1)1Brk	anemia	J:100202
	decreased birth body size	J:100202
	male infertility	J:100202
	pallor	J:100202
Del(1)1Brk/Del(1)1Brk involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J * CBA/J	abnormal erythrocyte morphology	J:103440
	abnormal hemoglobin	J:103440
	abnormal iron homeostasis	J:103440
	abnormal reticulocyte morphology	J:103440
	anisopoikilocytosis	J:103440
	decreased hematocrit	J:103440
	decreased hemoglobin content	J:103440
	decreased mean corpuscular hemoglobin	J:103440
	decreased mean corpuscular hemoglobin concentration	J:103440
	decreased mean corpuscular volume	J:103440
	increased erythrocyte cell number	J:103440
	increased liver iron level	J:103440
	reticulocytosis	J:103440
	thrombocytosis	J:103440
Del(1)1Brk/Del(1)1Brk involves: 129S6/SvEvTac * C57BL/6J * CBA/J	abnormal circulating iron level	J:100202
	abnormal erythrocyte morphology	J:100202
	abnormal iron homeostasis	J:100202
	abnormal iron level	J:100202
	abnormal liver iron level	J:100202
	abnormal respiration	J:130396
	abnormal respiratory motile cilium physiology	J:130396
	abnormal spermiogenesis	J:130396
	abnormal spleen morphology	J:100202
	abnormal spleen white pulp morphology	J:100202
	absent sperm flagellum	J:130396
	anisocytosis	J:100202
	anisopoikilocytosis	J:100202
	azoospermia	J:130396
	decreased hematocrit	J:100202
	decreased hemoglobin content	J:100202
	decreased mean corpuscular hemoglobin	J:100202
	decreased mean corpuscular hemoglobin concentration	J:100202
	decreased mean corpuscular volume	J:100202
	enlarged heart	J:100202
	enlarged liver	J:100202
	enlarged spleen	J:100202
	normal growth/size/body region phenotype	J:130396
	normal hearing/vestibular/ear phenotype	J:130396
	impaired mucociliary clearance	J:130396
	increased bone marrow cell number	J:100202
	increased leukocyte cell number	J:100202
	increased spleen red pulp amount	J:100202
	male infertility	J:100202, J:130396
	microcytic anemia	J:100202
	microcytosis	J:100202
	normal mortality/aging	J:100202
	normal nervous system phenotype	J:100202
	polychromatophilia	J:100202
	reticulocytosis	J:100202
	testis hypoplasia	J:100202
	thrombocytosis	J:100202
	normal vision/eye phenotype	J:130396

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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