Mrap2 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mrap2
melanocortin 2 receptor accessory protein 2
MGI:3609239

27 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mrap2^tm1.1Maj/Mrap2⁺ either: B6.129-Mrap2^tm1.1Maj or (involves: 129 * 129S6/SvEvTac)	increased body weight	J:199365
Mrap2^tm1.1Maj/Mrap2^tm1.1Maj either: B6.129-Mrap2^tm1.1Maj or (involves: 129 * 129S6/SvEvTac)	abnormal adrenaline level	J:199365
	abnormal intestinal absorption	J:199365
	abnormal noradrenaline level	J:199365
	normal behavior/neurological phenotype	J:199365
	decreased lean body mass	J:199365
	hepatic steatosis	J:199365
	normal homeostasis/metabolism phenotype	J:199365
	increased body length	J:199365
	increased brown adipose tissue amount	J:199365
	increased circulating leptin level	J:199365
	increased compensatory feeding amount	J:199365
	increased food intake	J:199365
	increased percent body fat/body weight	J:199365
	increased susceptibility to weight gain	J:199365
	increased total body fat amount	J:199365
	increased white fat cell size	J:199365
	obese	J:199365
	polyphagia	J:199365
Mrap2^tm1.2Maj/Mrap2^tm1.2Maj Tg(Sim1-cre)1Lowl/0 involves: 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * FVB/N	increased susceptibility to weight gain	J:199365
	obese	J:199365
Mrap2^{tm1a(EUCOMM)Wtsi}/Mrap2^{tm1a(EUCOMM)Wtsi} C57BL/6N-Mrap2^{tm1a(EUCOMM)Wtsi}/Wtsi	abnormal bone structure	J:211773
	decreased bone mineral content	J:211773
	decreased lean body mass	J:211773
	impaired glucose tolerance	J:211773
	increased circulating alkaline phosphatase level	J:211773
	increased circulating calcium level	J:211773
	increased circulating insulin level	J:211773
	increased fasting circulating glucose level	J:211773
	increased red blood cell distribution width	J:211773
	increased total body fat amount	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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