Bin2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Bin2
bridging integrator 2
MGI:3611448

14 phenotypes from 3 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Bin2^{em1(IMPC)Wtsi}/Bin2^{em1(IMPC)Wtsi} C57BL/6N-Bin2^{em1(IMPC)Wtsi}/Wtsi	absent pinna reflex	J:211773
	decreased mean corpuscular hemoglobin	J:211773
	increased mean platelet volume	J:211773
	thrombocytopenia	J:211773
Bin2^tm1.1Beni/Bin2^tm1.1Beni Tg(Pf4-icre)Q3Rsko/0 involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac	abnormal platelet activation	J:302510
	abnormal platelet calcium level	J:302510
	abnormal platelet physiology	J:302510
	decreased cerebral infarct size	J:302510
	decreased platelet aggregation	J:302510
	decreased susceptibility to induced thrombosis	J:302510
	decreased susceptibility to ischemic brain injury	J:302510
	normal hematopoietic system phenotype	J:302510
	increased bleeding time	J:302510
Bin2^tm1.2Beni/Bin2^tm1.2Beni involves: 129S6/SvEvTac * BALB/cJ * C57BL/6 * C57BL/6NTac	no abnormal phenotype detected	J:302510

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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