Dnaaf5 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Dnaaf5
dynein, axonemal assembly factor 5
MGI:3616079

25 phenotypes from 4 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Dnaaf5^em1(IMPC)Bay/Dnaaf5⁺ C57BL/6N-Dnaaf5^em1(IMPC)Bay/Bay	decreased lean body mass	J:211773
Dnaaf5^em1(IMPC)Bay/Dnaaf5^em1(IMPC)Bay C57BL/6N-Dnaaf5^em1(IMPC)Bay/Bay	preweaning lethality, complete penetrance	J:211773
Dnaaf5^em1Slb/Dnaaf5^em1Slb C57BL/6-Dnaaf5^em1Slb	abnormal brain ependyma motile cilium morphology	J:342770
	abnormal brain ependyma motile cilium physiology	J:342770
	abnormal respiratory motile cilium morphology	J:342770
	abnormal respiratory motile cilium physiology	J:342770
	normal cellular phenotype	J:342770
	normal embryo phenotype	J:342770
	enlarged brain ventricles	J:342770
	heterotaxia	J:342770
	immotile respiratory cilia	J:342770
	immotile sperm	J:342770
	lordokyphosis	J:342770
	male infertility	J:342770
	megacephaly	J:342770
	non-obstructive hydrocephaly	J:342770
	premature death	J:342770
	normal reproductive system phenotype	J:342770
	normal respiratory system phenotype	J:342770
	sinus inflammation	J:342770
	situs inversus	J:342770
Dnaaf5^em1Slb/Dnaaf5^em2Slb C57BL/6-Dnaaf5^em1Slb Dnaaf5^em2Slb	abnormal brain ependyma motile cilium morphology	J:342770
	abnormal respiratory motile cilium morphology	J:342770
	decreased body size	J:342770
	immotile respiratory cilia	J:342770
	megacephaly	J:342770
	non-obstructive hydrocephaly	J:342770
	premature death	J:342770
	prenatal lethality, incomplete penetrance	J:342770
	respiratory system phenotype	J:342770
	sinus inflammation	J:342770
Dnaaf5^em2Slb/Dnaaf5^em2Slb C57BL/6-Dnaaf5^em2Slb	preweaning lethality, complete penetrance	J:342770
Dnaaf5^em3Slb/Dnaaf5^em3Slb C57BL/6-Dnaaf5^em3Slb	embryonic lethality between implantation and placentation, complete penetrance	J:342770

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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