Mir451a Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mir451a
microRNA 451a
MGI:3619412

24 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mir144/Mir451a^tm1.1Mjwe/Mir144/Mir451a^tm1.1Mjwe Not Specified	abnormal physiological response to xenobiotic	J:163250
	anemia	J:163250
	decreased catalase activity	J:163250
	decreased hemoglobin content	J:163250
	decreased mean corpuscular hemoglobin	J:163250
	decreased mean corpuscular volume	J:163250
	increased cellular sensitivity to hydrogen peroxide	J:163250
	increased number of Heinz bodies	J:163250
	increased red blood cell distribution width	J:163250
	increased spleen weight	J:163250
	polychromatophilia	J:163250
	reticulocytosis	J:163250
	spleen hyperplasia	J:163250
Mir144/Mir451a^tm1.2Doca/Mir144/Mir451a^tm1.2Doca involves: 129P2/OlaHsd * 129S4/SvJaeSor * BALB/cJ	abnormal erythropoiesis	J:163418
	anemia	J:163418
	anisocytosis	J:163418
	decreased erythrocyte cell number	J:163418
	decreased hematocrit	J:163418
	decreased hemoglobin content	J:163418
	enlarged spleen	J:163418
	increased erythroid progenitor cell number	J:163418
	increased red blood cell distribution width	J:163418
	increased susceptibility to xenobiotic induced morbidity/mortality	J:163418
Mir451a^tm1.2Doca/Mir451a^tm1.2Doca involves: 129P2/OlaHsd * 129S4/SvJaeSor * BALB/cJ	abnormal hematopoietic system morphology/development	J:163418
	decreased erythrocyte cell number	J:163418
	decreased hematocrit	J:163418
	enlarged spleen	J:163418
	increased erythroid progenitor cell number	J:163418
	increased red blood cell distribution width	J:163418
Mir451a^tm1Eno/Mir451a⁺ involves: C57BL/6	abnormal erythrocyte cell number	J:163251
Mir451a^tm1Eno/Mir451a^tm1Eno involves: C57BL/6	abnormal fetal derived definitive erythrocyte cell number	J:163251
	enlarged spleen	J:163251
	increased erythroid progenitor cell number	J:163251
	increased physiological sensitivity to xenobiotic	J:163251

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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