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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Sh2d1b2
SH2 domain containing 1B2
MGI:3622649
3 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Sh2d1b1/Sh2d1b2tm1.1Cpt/Sh2d1b1/Sh2d1b2tm1.1Cpt
involves: BALB/cJ 		decreased interferon-gamma secretion J:166054
impaired natural killer cell mediated cytotoxicity J:166054
Sh2d1b2tm1.1Cpt/Sh2d1b2tm1.1Cpt
involves: BALB/cJ * C57BL/6 		impaired natural killer cell mediated cytotoxicity J:166054
Sh2d1b2tm1Vei/Sh2d1b2tm1Vei
involves: 129S1/Sv * 129X1/SvJ 		impaired natural killer cell mediated cytotoxicity J:145969
increased natural killer cell mediated cytotoxicity J:110195
Tg(CD2-Sh2d1b2)#Vei/0
B6.Cg-Tg(CD2-Sh2d1b2)#Vei 		impaired natural killer cell mediated cytotoxicity J:110195
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory