Apela Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Apela
apelin receptor early endogenous ligand
MGI:3642370

30 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Apela^em1Shx/Apela^em1Shx involves: C57BL/6J * CBA/Ca2J	no abnormal phenotype detected	J:330639
Apela^tm1.2Brre/Apela⁺ B6(Cg)-Apela^tm1.2Brre	abnormal litter size	J:244834
Apela^tm1.2Brre/Apela⁺ B6(Cg)-Apela^tm1.2Brre	maternal effect	J:244834
Apela^tm1.2Brre/Apela^tm1.2Brre B6(Cg)-Apela^tm1.2Brre	abnormal angiogenesis	J:244834
	abnormal cardiovascular system morphology	J:244834
	abnormal dorsal aorta morphology	J:244834
	abnormal glomerular capillary endothelium morphology	J:244834
	abnormal heart tube morphology	J:244834
	abnormal intersomitic artery morphology	J:244834
	abnormal litter size	J:244834
	abnormal placenta morphology	J:244834
	abnormal placental labyrinth vasculature morphology	J:244834
	abnormal syncytiotrophoblast morphology	J:244834
	abnormal vascular development	J:244834
	abnormal visceral yolk sac morphology	J:244834
	absent cardiac outflow tract	J:244834
	absent glomerular endothelium fenestra	J:244834
	absent vitelline blood vessels	J:244834
	decreased embryo weight	J:244834
	normal embryo phenotype	J:244834
	embryonic growth retardation	J:244834
	glomerular capillary congestion	J:244834
	increased placenta apoptosis	J:244834
	increased systemic arterial blood pressure	J:244834
	increased urine protein level	J:244834
	lethality, incomplete penetrance	J:244834
	maternal effect	J:244834
	pale yolk sac	J:244834
	pericardial edema	J:244834
	renal glomerular protein deposits	J:244834
	normal renal/urinary system phenotype	J:244834
	thin placenta labyrinth	J:244834

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/05/2024 MGI 6.24