Apela Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Apela
apelin receptor early endogenous ligand
MGI:3642370

30 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Apela^em1Shx/Apela^em1Shx involves: C57BL/6J * CBA/Ca2J	no abnormal phenotype detected	J:330639
Apela^tm1.2Brre/Apela⁺ B6(Cg)-Apela^tm1.2Brre	abnormal litter size	J:244834
Apela^tm1.2Brre/Apela⁺ B6(Cg)-Apela^tm1.2Brre	maternal effect	J:244834
Apela^tm1.2Brre/Apela^tm1.2Brre B6(Cg)-Apela^tm1.2Brre	abnormal angiogenesis	J:244834
	abnormal cardiovascular system morphology	J:244834
	abnormal dorsal aorta morphology	J:244834
	abnormal glomerular capillary endothelium morphology	J:244834
	abnormal heart tube morphology	J:244834
	abnormal intersomitic artery morphology	J:244834
	abnormal litter size	J:244834
	abnormal placenta morphology	J:244834
	abnormal placental labyrinth vasculature morphology	J:244834
	abnormal syncytiotrophoblast morphology	J:244834
	abnormal vascular development	J:244834
	abnormal visceral yolk sac morphology	J:244834
	absent cardiac outflow tract	J:244834
	absent glomerular endothelium fenestra	J:244834
	absent vitelline blood vessels	J:244834
	decreased embryo weight	J:244834
	normal embryo phenotype	J:244834
	embryonic growth retardation	J:244834
	glomerular capillary congestion	J:244834
	increased placenta apoptosis	J:244834
	increased systemic arterial blood pressure	J:244834
	increased urine protein level	J:244834
	lethality, incomplete penetrance	J:244834
	maternal effect	J:244834
	pale yolk sac	J:244834
	pericardial edema	J:244834
	renal glomerular protein deposits	J:244834
	normal renal/urinary system phenotype	J:244834
	thin placenta labyrinth	J:244834

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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