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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Alkal2
ALK and LTK ligand 2
MGI:3697448
30 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Alkal2em1(IMPC)J/Alkal2+
C57BL/6NJ-Alkal2em1(IMPC)J/Mmjax 		abnormal skin morphology J:211773
decreased grip strength J:211773
Alkal2em1(IMPC)J/Alkal2em1(IMPC)J
C57BL/6NJ-Alkal2em1(IMPC)J/Mmjax 		cornea opacity J:211773
exophthalmos J:211773
increased bone mineral content J:211773
narrow eye opening J:211773
Alkal2tm1a(EUCOMM)Hmgu/Alkal2tm1a(EUCOMM)Hmgu
involves: C57BL/6N 		browned white adipose tissue morphology J:324631
decreased body weight J:324631
decreased gonadal fat pad weight J:324631
decreased percent body fat/body weight J:324631
decreased retroperitoneal fat pad weight J:324631
decreased subcutaneous adipose tissue amount J:324631
decreased susceptibility to diet-induced obesity J:324631
decreased white adipose tissue amount J:324631
decreased white fat cell size J:324631
hyperactivity J:324631
improved glucose tolerance J:324631
increased carbon dioxide production J:324631
increased energy expenditure J:324631
increased insulin sensitivity J:324631
increased lean body mass J:324631
increased noradrenaline level J:324631
increased oxygen consumption J:324631
increased respiratory quotient J:324631
slow postnatal weight gain J:324631
thin body J:324631
Alkal2tm1Schl/Alkal2tm1Schl
involves: C57BL/6 		browned white adipose tissue morphology J:324631
decreased body weight J:324631
decreased compensatory feeding amount J:324631
decreased fluid intake J:324631
decreased gonadal fat pad weight J:324631
decreased percent body fat/body weight J:324631
decreased retroperitoneal fat pad weight J:324631
decreased subcutaneous adipose tissue amount J:324631
decreased white adipose tissue amount J:324631
decreased white fat cell size J:324631
hyperactivity J:324631
hyperactivity elicited by feed restriction J:324631
improved glucose tolerance J:324631
increased carbon dioxide production J:324631
increased energy expenditure J:324631
increased fluid intake J:324631
increased insulin sensitivity J:324631
increased lean body mass J:324631
increased noradrenaline level J:324631
increased oxygen consumption J:324631
increased respiratory quotient J:324631
slow postnatal weight gain J:324631
thin body J:324631
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory