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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Dp(16Lipi-Zbtb21)1Yey
duplication, Chr 16, Y Eugene Yu 1
MGI:3714521
43 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Del(16Cbr1-Fam3b)1Rhr/Dp(16Lipi-Zbtb21)1Yey
involves: 129S6/SvEvTac * 129S7/SvEvBrd * C3H/HeJ * C3H/HeSnJ * C57BL/6 * C57BL/LiA 		impaired contextual conditioning behavior J:224899
Del(16Dyrk1a-Kcnj6)14Yey/Dp(16Lipi-Zbtb21)1Yey
B6.129S7-Del(16Dyrk1a-Kcnj6)14Yey/Dp(16Lipi-Zbtb21)1Yey 		decreased exploration in new environment J:224899
impaired contextual conditioning behavior J:224899
reduced long-term potentiation J:224899
Del(16Kcnj15-Mx2)13Yey/Dp(16Lipi-Zbtb21)1Yey
B6.129S7-Del(16Kcnj15-Mx2)13Yey/Dp(16Lipi-Zbtb21)1Yey 		decreased exploration in new environment J:224899
impaired contextual conditioning behavior J:224899
reduced long-term potentiation J:224899
Del(16Setd4-Kcnj6)12Yey/Dp(16Lipi-Zbtb21)1Yey
B6.129S7-Del(16Setd4-Kcnj6)12Yey/Dp(16Lipi-Zbtb21)1Yey 		decreased exploration in new environment J:224899
impaired contextual conditioning behavior J:224899
reduced long-term potentiation J:224899
Dp(10Prmt2-Pdxk)2Yey/0
Dp(16Lipi-Zbtb21)1Yey/0
B6.129S7-Dp(10Prmt2-Pdxk)2Yey Dp(16Lipi-Zbtb21)1Yey 		neonatal lethality J:161325
Dp(10Prmt2-Pdxk)2Yey/0
Dp(16Lipi-Zbtb21)1Yey/0
Dp(17Abcg1-Rrp1b)3Yey/0
B6.129S7-Dp(10Prmt2-Pdxk)2Yey Dp(16Lipi-Zbtb21)1Yey Dp(17Abcg1-Rrp1b)3Yey 		abnormal heart morphology J:161325
abnormal spatial learning J:161325
abnormal spatial reference memory J:161325
cerebral aqueductal stenosis J:161325
decreased grip strength J:161325
decreased survivor rate J:161325
dilated lateral ventricle J:161325
impaired contextual conditioning behavior J:161325
impaired swimming J:161325
neonatal lethality, incomplete penetrance J:161325
obstructive hydrocephaly J:161325
premature death J:161325
reduced long-term potentiation J:161325
normal reproductive system phenotype J:161325
Dp(16Lipi-Zbtb21)1Yey/0
B6.129S7-Dp(16Lipi-Zbtb21)1Yey 		decreased exploration in new environment J:224899
hydrocephaly J:241597
impaired contextual conditioning behavior J:224899
premature death J:241597
reduced long-term potentiation J:224899
transmission ratio distortion J:224899
Dp(16Lipi-Zbtb21)1Yey/0
B6.129S7-Dp(16Lipi-Zbtb21)1Yey/J 		abnormal CNS synaptic transmission J:351206
abnormal excitatory postsynaptic potential J:351206
abnormal inhibitory postsynaptic currents J:351206
abnormal postsynaptic density morphology J:351206
abnormal spatial reference memory J:351206
decreased dendritic spine density J:351206
decreased excitatory postsynaptic current frequency J:351206
impaired contextual conditioning behavior J:351206
impaired cued conditioning behavior J:351206
impaired spatial learning J:351206
reduced long-term potentiation J:351206
Dp(16Lipi-Zbtb21)1Yey/0
involves: 129S7/SvEvBrd 		abnormal heart morphology J:121790
abnormal intestine morphology J:121790
abnormal mitral valve morphology J:121790
annular pancreas J:121790
aorta coarctation J:121790
atrial septal defect J:121790
double outlet right ventricle J:121790
heart right ventricle outflow tract stenosis J:121790
overriding aortic valve J:121790
perimembraneous ventricular septal defect J:121790
postnatal lethality J:121790
subarterial ventricular septal defect J:121790
Dp(16Lipi-Zbtb21)1Yey/Del(16Ifnar1-Kcnj6)11Yey
involves: 129S7/SvEvBrd * C57BL/6J 		normal mortality/aging J:208104
Dp(16Lipi-Zbtb21)1Yey/Del(16Tiam1-Kcnj6)7Yey
involves: 129S7/SvEvBrd 		normal cardiovascular system phenotype J:180201
no abnormal phenotype detected J:180201
Dp(16Lipi-Zbtb21)1Yey/Dp(16Lipi-Zbtb21)1Yey
involves: 129/Sv * 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 		embryonic lethality, complete penetrance J:224899
Dp(16Lipi-Zbtb21)1Yey/0
Dp(17Abcg1-Rrp1b)3Yey/0
B6.129S7-Dp(16Lipi-Zbtb21)1Yey Dp(17Abcg1-Rrp1b)3Yey 		neonatal lethality J:161325
Dp(16Lipi-Zbtb21)1Yey/0
Dyrk1aGt(XQ0369)Wtsi/Dyrk1a+
involves: 129/Sv * 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6 		decreased exploration in new environment J:224899
impaired contextual conditioning behavior J:224899
Dp(16Lipi-Zbtb21)1Yey/Zbtb21em1Jhan
B6.Cg-Dp(16Lipi-Zbtb21)1Yey Zbtb21em1Jhan 		abnormal inhibitory postsynaptic currents J:351206
normal behavior/neurological phenotype J:351206
normal nervous system phenotype J:351206
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/19/2024
MGI 6.24 		The Jackson Laboratory