Pcdhg Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Pcdhg
protocadherin gamma cluster
MGI:3719124

36 phenotypes from 14 alleles in 13 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Pcdhg^em5Rwb/Pcdhg^em5Rwb C57BL/6J-Pcdhg^em5Rwb/Rwb	abnormal spinal cord grey matter morphology	J:285314
	abnormal spinal cord interneuron morphology	J:285314
	abnormal spinal cord morphology	J:285314
	abnormal spinal cord ventral horn morphology	J:285314
	astrocytosis	J:285314
	decreased spinal cord size	J:285314
	hunched posture	J:285314
	impaired righting response	J:285314
	increased spinal cord apoptosis	J:285314
	microgliosis	J:285314
	neonatal lethality, complete penetrance	J:285314
	tremors	J:285314
Pcdhg^em5Rwb/Pcdhg^tm2Xzw Tg(Pax6-cre,GFP)2Pgr/0 involves: 129S7/SvEvBrd * C57BL/6J	decreased amacrine cell number	J:285314
	decreased retina ganglion cell number	J:285314
	decreased total retina thickness	J:285314
	thin retina inner nuclear layer	J:285314
	thin retina inner plexiform layer	J:285314
Pcdhg^em8Rwb/Pcdhg^em8Rwb Not Specified	no abnormal phenotype detected	J:285314
Pcdhg^em35Rwb/Pcdhg^em35Rwb C57BL/6J-Pcdhg^em35Rwb/Rwb	no abnormal phenotype detected	J:285314
Pcdhg^em41Rwb/Pcdhg^em41Rwb C57BL/6J-Pcdhg^em41Rwb/Rwb	abnormal spinal cord interneuron morphology	J:285314
	abnormal spinal cord morphology	J:285314
	abnormal spinal cord ventral horn morphology	J:285314
	decreased spinal cord size	J:285314
	hunched posture	J:285314
	impaired righting response	J:285314
	increased spinal cord apoptosis	J:285314
	microgliosis	J:285314
	neonatal lethality, complete penetrance	J:285314
	tremors	J:285314
Pcdhg^tm1.1Sch/Pcdhg^tm1.1Sch involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6	perinatal lethality, complete penetrance	J:98737
Pcdhg^tm1.1Tman/Pcdhg^tm1.1Tman involves: 129S4/SvJae * C57BL/6	abnormal reflex	J:188341
	abnormal voluntary movement	J:188341
	astrocytosis	J:188341
	hunched posture	J:188341
	increased neuron apoptosis	J:188341
	microgliosis	J:188341
	muscle hypertonia	J:188341
	neonatal lethality, complete penetrance	J:188341
	neuron degeneration	J:188341
	tremors	J:188341
	umbilical hernia	J:188341
Pcdhg^tm1.2Sch/Pcdhg^tm1.2Sch B6.129-Pcdhg^tm1.2Sch	abnormal dendrite morphology	J:195283
	abnormal olfactory bulb development	J:195283
	decreased dendritic spine number	J:195283
	normal nervous system phenotype	J:195283
Pcdhg^tm1Sch/Pcdhg^tm1Sch involves: 129S1/Sv * 129X1/SvJ * C57BL/6	perinatal lethality, complete penetrance	J:98737
Pcdhg^tm1Xzw/Pcdhg^tm1Xzw involves: 129S7/SvEvBrd	no abnormal phenotype detected	J:107735
Pcdhg^tm2.1Tman/Pcdhg^tm2.1Tman involves: 129S4/SvJae * C57BL/6	no abnormal phenotype detected	J:188341
Pcdhg^tm2.1Xzw/Pcdhg^tm2.1Xzw involves: 129S7/SvEvBrd * C57BL/6J * FVB/N	abnormal spinal cord morphology	J:142186
	neonatal lethality, complete penetrance	J:142186
Pcdhg^tm2Xzw/Pcdhg^tm2Xzw involves: 129S7/SvEvBrd * C57BL/6 * CD-1	abnormal Purkinje cell dendrite morphology	J:221288
Pcdhg^tm2Xzw/Pcdhg^tm2Xzw Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL	abnormal eye electrophysiology	J:142186
	increased retina apoptosis	J:142186
	thin retina inner nuclear layer	J:142186
	thin retina inner plexiform layer	J:142186
Pcdhg^tm2Xzw/Pcdhg^tm2Xzw Tg(Pax6-cre,GFP)2Pgr/0 involves: 129S7/SvEvBrd * C57BL/6J	abnormal Muller cell morphology	J:142186
	abnormal retina bipolar cell morphology	J:142186
	decreased amacrine cell number	J:142186
	decreased retina ganglion cell number	J:142186
	normal vision/eye phenotype	J:142186
Pcdhg^tm3.1Xzw/Pcdhg^tm3.1Xzw involves: 129S7/SvEvBrd * C57BL/6J * FVB/N	abnormal spinal cord morphology	J:142186
	neonatal lethality, complete penetrance	J:142186
Pcdhg^tm3Xzw/Pcdhg^tm3Xzw Tg(Chx10-EGFP/cre,-ALPP)2Clc/0 involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL	abnormal retina morphology	J:142186
	decreased total retina thickness	J:142186
	thin retina inner nuclear layer	J:142186
	thin retina inner plexiform layer	J:142186

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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