Del(MTmt-Tk-mt-Nd5)1Jiha Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Del(MTmt-Tk-mt-Nd5)1Jiha
deletion, MT, Jun-Ichi Hayashi 1
MGI:3776661

43 phenotypes from 1 allele in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Del(MTmt-Tk-mt-Nd5)1Jiha involves: C57BL/6J * CBA	abnormal mitochondrial ATP synthesis coupled electron transport	J:72614, J:92536, J:103743, J:115155, J:132407
	abnormal mitochondrial crista morphology	J:72614
	abnormal postnatal growth	J:103743
	abnormal sperm midpiece morphology	J:115155
	abnormal sperm nucleus morphology	J:115155
	absent sperm head	J:115155
	arrest of male meiosis	J:115155
	asthenozoospermia	J:115155
	deafness	J:115155
	decreased body weight	J:103743, J:115155
	decreased circulating glucose level	J:92536
	decreased germ cell number	J:115155
	decreased litter size	J:115155
	dilated distal convoluted tubule	J:103743
	dilated mitochondrion	J:72614
	dilated proximal convoluted tubule	J:103743
	dilated renal tubule	J:132407
	enlarged kidney	J:103743, J:132407
	glomerulosclerosis	J:132407
	heart block	J:115155
	impaired hearing	J:92536
	increased blood urea nitrogen level	J:103743
	increased circulating insulin level	J:92536
	increased circulating lactate level	J:103743
	increased insulin secretion	J:92536
	increased pancreatic alpha cell number	J:92536
	increased pancreatic beta cell number	J:92536
	kidney failure	J:115155
	lactic acidosis	J:115155
	male infertility	J:115155
	myopathy	J:115155
	oligozoospermia	J:115155
	pale kidney	J:132407
	pancreatic islet hyperplasia	J:92536
	premature death	J:103743
	reduced male mating frequency	J:115155
	teratozoospermia	J:115155
Del(MTmt-Tk-mt-Nd5)1Jiha involves: C57BL/6J * CBA * DBA/2	abnormal blood circulation	J:65025
	abnormal mitochondrial ATP synthesis coupled electron transport	J:65025
	anemia	J:65025
	enlarged kidney	J:65025
	increased blood urea nitrogen level	J:65025
	increased circulating creatinine level	J:65025
	kidney failure	J:65025
	premature death	J:65025
Del(MTmt-Tk-mt-Nd5)1Jiha involves: C57BL/6JJcl * C57BL/6NCrlj * CBA/JNCrlj	abnormal oxidative phosphorylation	J:199416
	decreased circulating glucose level	J:199416
	normal integument phenotype	J:199416
	kyphosis	J:199416
	premature death	J:199416

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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