About   Help   FAQ
Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Mirc1
microRNA cluster 1, including Mir17 through Mir92-1
MGI:3790484
44 phenotypes from 9 alleles in 12 genetic backgrounds
Export: Excel File
Allelic Composition
Genetic Background		 Annotated Term Reference
Mirc1tm1.1Aven/Mirc1+
B6.Cg-Mirc1tm1.1Aven 		brachyphalangia J:223213
vertebral fusion J:223213
Mirc1tm1.1Aven/Mirc1tm1.1Aven
B6.Cg-Mirc1tm1.1Aven 		abnormal rostral-caudal axis patterning J:223213
brachyphalangia J:223213
delayed bone ossification J:223213
fused carpal bones J:223213
lumbar vertebral transformation J:223213
perinatal lethality, incomplete penetrance J:223213
thoracic vertebral transformation J:223213
vertebral fusion J:223213
Mirc1tm1.1Aven/Mirc1tm1.1Aven
involves: 129S4/SvJae * C57BL/6 * SJL/J 		decreased alpha-beta T cell number J:223213
decreased B cell number J:223213
decreased body weight J:223213
decreased myeloid cell number J:223213
decreased pre-B cell number J:223213
decreased pro-B cell number J:223213
increased B cell apoptosis J:223213
small spleen J:223213
Mirc1tm1.1Tyj/Mirc1tm1.1Tyj
involves: 129S4/SvJae * C57BL/6 * SJL 		no abnormal phenotype detected J:134861
Mirc1tm1.2Tyj/Mirc1+
B6.Cg-Mirc1tm1.2Tyj 		brachyphalangia J:223213
fused carpal bones J:223213
lumbar vertebral transformation J:223213
Mirc1tm1.2Tyj/Mirc1+
involves: 129S4/SvJae * C57BL/6 		brachyphalangia J:188762
decreased body size J:188762
decreased body weight J:223213
microcephaly J:188762
Mirc1tm1.2Tyj/Mirc1+
involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL 		decreased body size J:134861
Mirc1tm1.2Tyj/Mirc1tm1.2Tyj
B6.Cg-Mirc1tm1.2Tyj 		abnormal phalanx morphology J:223213
abnormal rostral-caudal axis patterning J:223213
cleft palate J:223213
delayed bone ossification J:223213
fused carpal bones J:223213
lumbar vertebral transformation J:223213
perinatal lethality, complete penetrance J:223213
syndactyly J:223213
thoracic vertebral transformation J:223213
vertebral fusion J:223213
vertebral transformation J:223213
Mirc1tm1.2Tyj/Mirc1tm1.2Tyj
involves: 129S4/SvJae * C57BL/6 		abnormal forelimb zeugopod morphology J:188762
abnormal hindlimb zeugopod morphology J:188762
abnormal phalanx morphology J:188762
brachyphalangia J:188762
cervical vertebral fusion J:188762
decreased heart right ventricle size J:169047
delayed endochondral bone ossification J:188762
delayed intramembranous bone ossification J:188762
double outlet right ventricle J:169047
fused carpal bones J:188762
microcephaly J:188762
perinatal lethality, complete penetrance J:223213
pulmonary hypoplasia J:223213
ventricular septal defect J:169047, J:223213
Mirc1tm1.2Tyj/Mirc1tm1.2Tyj
involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL 		abnormal B cell differentiation J:134861
abnormal interventricular septum morphology J:134861
decreased embryo size J:134861
decreased embryo weight J:134861
decreased pre-B cell number J:134861
increased B cell apoptosis J:134861
neonatal lethality, complete penetrance J:134861
pulmonary hypoplasia J:134861
Mirc1tm1.3Tyj/Mirc1tm1.3Tyj
involves: 129S4/SvJae * C57BL/6 * FVB/N 		abnormal B cell differentiation J:134861
abnormal interventricular septum morphology J:134861
decreased embryo size J:134861
decreased embryo weight J:134861
decreased pre-B cell number J:134861
increased B cell apoptosis J:134861
neonatal lethality, complete penetrance J:134861
pulmonary hypoplasia J:134861
Mirc1tm1Tyj/Mirc1tm1Tyj
Tg(Mx1-cre)1Cgn/0
involves: 129S4/SvJae * C57BL/6 * CBA * SJL 		abnormal immunoglobulin heavy chain V(D)J recombination J:134861
decreased pre-B cell number J:134861
increased B cell apoptosis J:134861
Mirc1tm2.1Aven/Mirc1tm2.1Aven
B6.Cg-Mirc1tm2.1Aven 		perinatal lethality, incomplete penetrance J:223213
vertebral fusion J:223213
Mirc1tm2.1Aven/Mirc1tm2.1Aven
involves: 129S4/SvJae * C57BL/6 * SJL/J 		decreased B cell number J:223213
decreased myeloid cell number J:223213
Mirc1tm3.1Aven/Mirc1+
B6.Cg-Mirc1tm3.1Aven 		brachyphalangia J:223213
Mirc1tm3.1Aven/Mirc1+
involves: 129S4/SvJae * C57BL/6 * SJL/J 		decreased body weight J:223213
Mirc1tm3.1Aven/Mirc1tm3.1Aven
B6.Cg-Mirc1tm3.1Aven 		abnormal rostral-caudal axis patterning J:223213
brachyphalangia J:223213
delayed bone ossification J:223213
fused carpal bones J:223213
lumbar vertebral transformation J:223213
perinatal lethality, incomplete penetrance J:223213
thoracic vertebral transformation J:223213
vertebral fusion J:223213
vertebral transformation J:223213
Mirc1tm3.1Aven/Mirc1tm3.1Aven
involves: 129S4/SvJae * C57BL/6 * SJL/J 		decreased alpha-beta T cell number J:223213
decreased B cell number J:223213
decreased body weight J:223213
decreased myeloid cell number J:223213
decreased pre-B cell number J:223213
decreased pro-B cell number J:223213
increased B cell apoptosis J:223213
small spleen J:223213
Mirc1tm4.1Aven/Mirc1+
B6.Cg-Mirc1tm4.1Aven 		brachyphalangia J:223213
Mirc1tm4.1Aven/Mirc1+
involves: 129S4/SvJae * C57BL/6 * SJL/J 		decreased body weight J:223213
Mirc1tm4.1Aven/Mirc1tm4.1Aven
B6.Cg-Mirc1tm4.1Aven 		abnormal phalanx morphology J:223213
cleft palate J:223213
delayed bone ossification J:223213
fused carpal bones J:223213
lumbar vertebral transformation J:223213
perinatal lethality, complete penetrance J:223213
thoracic vertebral transformation J:223213
vertebral fusion J:223213
Mirc1tm4.1Aven/Mirc1tm4.1Aven
involves: 129S4/SvJae * C57BL/6 * SJL/J 		perinatal lethality, complete penetrance J:223213
pulmonary hypoplasia J:223213
Tg(Sftpc-Mirn17-92)1Blh/0
involves: FVB * ICR 		abnormal lung development J:128019
abnormal lung morphology J:128019
abnormal pulmonary alveolus morphology J:128019
atelectasis J:128019
perinatal lethality, incomplete penetrance J:128019
pulmonary hyperplasia J:128019
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory