Mirc1 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mirc1
microRNA cluster 1, including Mir17 through Mir92-1
MGI:3790484

28 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Bmp4^tm1Jfm/Bmp4^tm1Jfm Mirc1^tm1.2Tyj/Mirc1^tm1.2Tyj Tg(Mef2c-cre)2Blk/0 involves: 129S4/SvJaeSor * C57BL/6	abnormal cardiac outflow tract development	J:169047
	abnormal truncus arteriosus septation	J:169047
Mirc1^tm1.1Tyj/Mirc1^tm1.1Tyj Pkd1^tm1.1Pcha/Pkd1^tm1.1Pcha Tg(Cdh16-cre)91Igr/0 involves: 129 * 129S4/SvJae * C57BL/6 * ICR	decreased blood urea nitrogen level	J:244067
	normal renal/urinary system phenotype	J:244067
Mirc1^tm1.1Tyj/Mirc1^tm1.1Tyj Pkd1^tm1.1Pcha/Pkd1^tm2Som Tg(Cdh16-cre)91Igr/0 involves: 129 * 129S4/SvJae * C57BL/6 * ICR	abnormal peroxisome morphology	J:244067
	abnormal redox activity	J:244067
	decreased circulating creatinine level	J:244067
	decreased kidney cell proliferation	J:244067
	decreased kidney weight	J:244067
	increased fatty acid oxidation	J:244067
	kidney cyst	J:244067
	normal renal/urinary system phenotype	J:244067
Mirc1^tm1.1Tyj/Mirc1^tm1.1Tyj Pkd1^tm2Som/Pkd1^tm2Som Tg(Cdh16-cre)91Igr/0 involves: 129S4/SvJae * C57BL/6 * ICR	decreased circulating creatinine level	J:244067
	decreased kidney cell proliferation	J:244067
	decreased kidney weight	J:244067
	premature death	J:244067
Mirc1^tm1.1Tyj/Mirc1^tm1.1Tyj Pkd2^tm3Som/Pkd2^tm3Som Tg(Pkhd1-cre)1Igr/0 involves: 129S4/SvJae * C57BL/6	decreased circulating creatinine level	J:244067
	decreased kidney cell proliferation	J:244067
	kidney cyst	J:244067
	premature death	J:244067
Mirc1^tm2.1Aven/Mirc1⁺ Tg(IghMyc)22Bri/? involves: 129S4/SvJae * C57BL/6 * SJL/J	abnormal survival	J:223213
Mirc1^tm2.1Aven/Mirc1^tm2.1Aven Tg(ARR2/Pbsn-MYC)7Key/0 involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL/J	decreased prostate gland tumor incidence	J:223213
	increased prostate gland adenocarcinoma incidence	J:223213
	small prostate gland	J:223213
Mirc1^tm2.1Aven/Mirc1^tm2.1Aven Tg(IghMyc)22Bri/? involves: 129S4/SvJae * C57BL/6 * SJL/J	abnormal pre-B cell morphology	J:223213
	abnormal survival	J:223213
	increased B cell apoptosis	J:223213
	increased B cell derived lymphoma incidence	J:223213
	increased tumor latency	J:223213
Mirc2^tm1.1Tyj/Y Mirc3^tm1.1Tyj/Mirc3⁺ Mirc1^tm1.2Tyj/Mirc1⁺ involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL	no abnormal phenotype detected	J:134861
Mirc2^tm1.1Tyj/Y Mirc3^tm1.1Tyj/Mirc3^tm1.1Tyj Mirc1^tm1.2Tyj/Mirc1⁺ involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL	no abnormal phenotype detected	J:134861
Mirc2^tm1.1Tyj/Y Mirc3^tm1.1Tyj/Mirc3^tm1.1Tyj Mirc1^tm1.2Tyj/Mirc1^tm1.2Tyj involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL	atrial septal defect	J:134861
	increased apoptosis	J:134861
	prenatal lethality, complete penetrance	J:134861
	thin ventricular wall	J:134861
	ventricular septal defect	J:134861
Mirc3^tm1.1Tyj/Mirc3^tm1.1Tyj Mirc1^tm1.2Tyj/Mirc1⁺ involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL	no abnormal phenotype detected	J:134861
Mirc3^tm1.1Tyj/Mirc3^tm1.1Tyj Mirc1^tm1.2Tyj/Mirc1^tm1.2Tyj involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL	atrial septal defect	J:134861
	blood vessel congestion	J:134861
	edema	J:134861
	increased apoptosis	J:134861
	prenatal lethality, complete penetrance	J:134861
	thin ventricular wall	J:134861
	ventricular septal defect	J:134861

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