n-TUtca2 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

n-TUtca2
nuclear encoded tRNA selenocysteine 2 (anticodon TCA)
MGI:4414022

10 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Nfe2l2^tm1Mym/Nfe2l2^tm1Mym n-TUtca2^tm2Mym/n-TUtca2^tm2.1Mym Lyz2^tm1(cre)Ifo/Lyz2⁺ involves: 129P2/OlaHsd * C57BL/6 * DBA/2	increased apoptosis	J:130723
	increased cellular sensitivity to hydrogen peroxide	J:130723
	increased cellular sensitivity to oxidative stress	J:130723
Nfe2l2^tm1Mym/Nfe2l2^tm1Mym Tg(Alb1-cre)1Dlr/0 n-TUtca2^tm2Mym/n-TUtca2^tm2.1Mym involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N	abnormal hepatocyte morphology	J:130723
	increased circulating alanine transaminase level	J:130723
	increased hepatocyte apoptosis	J:130723
	lethality at weaning, incomplete penetrance	J:130723
	liver degeneration	J:130723
	pale liver	J:130723
	premature death	J:130723

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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