Mirc13 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mirc13
microRNA cluster 13, including Mir141 through Mir200c
MGI:5313565

22 phenotypes from 3 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Mirc13^tm1.1Mtm/Mirc13^tm1.1Mtm involves: 129P2/OlaHsd * C57BL/6 * FVB	normal mortality/aging	J:181752
Mirc13^tm1.1Mtm/Mirc13^tm1.1Mtm Not Specified	abnormal lipid homeostasis	J:256444
	abnormal lipid metabolism	J:256444
	abnormal macrophage activation involved in immune response	J:256444
	abnormal metabolism	J:256444
	abnormal phospholipid level	J:256444
	abnormal sphingomyelin level	J:256444
	decreased fasting circulating glucose level	J:256444
	decreased lipogenesis	J:256444
	decreased liver triglyceride level	J:256444
	decreased liver weight	J:256444
	decreased saturated fatty acids level	J:256444
	decreased susceptibility to diet-induced hepatic steatosis	J:256444
	normal growth/size/body region phenotype	J:256444
	increased bile salt level	J:256444
	increased ceramide level	J:256444
Mirc13^tm1Biat/Mirc13^tm1Biat involves: C57BL/6J * C57BL/6N	abnormal circulating glucose level	J:314874
	normal abnormal glucose homeostasis	J:314874
	abnormal pancreatic beta cell apoptosis	J:314874
	decreased physiological sensitivity to xenobiotic	J:314874
	normal decreased susceptibility to diet-induced obesity	J:314874
Mirc13^tm1Wtsi/Mirc13^tm1Wtsi C57BL/6N-Mirc13^tm1Wtsi/Mhzh	preweaning lethality, complete penetrance	J:211773

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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