Mirc21 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Mirc21
microRNA cluster 21, including Mir34c through Mir34b
MGI:5313578

34 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Mir34a^tm1.1Aven/Mir34a^tm1.1Aven Mirc21^tm1.1Aven/Mirc21^tm1.1Aven Mirc34^em1Jnch/Mirc34^em1Jnch involves: 129S4/SvJae * C57BL/6 * FVB/N	abnormal locomotor coordination	J:304721
	abnormal motor neuron morphology	J:304721
	blepharoptosis	J:304721
	decreased body weight	J:304721
	decreased locomotor activity	J:304721
	decreased thermal nociceptive threshold	J:304721
	hunched posture	J:304721
	jumpy	J:304721
	microphthalmia	J:304721
	normal nervous system phenotype	J:304721
	postnatal growth retardation	J:304721
	postnatal lethality, incomplete penetrance	J:304721
	premature death	J:304721
Mir34a^tm1.1Aven/Mir34a^tm1.1Aven Mirc21^tm1.1Aven/Mirc21^tm1.1Aven Mirc34^em1Jnch/Mirc34^em1Jnch Tg(Hlxb9-GFP)1Tmj/0 involves: 129S4/SvJae * C57BL/6 * CBA * FVB/N	normal nervous system phenotype	J:304721
Mir34a^tm1.1Kry/Mir34a^tm1.1Kry Mirc21^tm1.1Kry/Mirc21^tm1.1Kry Tg(Col1a1-cre)1Kry/0 involves: 129S4/SvJaeSor * 129S6/SvEvTac * FVB/N	abnormal skeleton development	J:185130
	increased bone mass	J:185130
	increased osteoblast cell number	J:185130
	normal skeleton phenotype	J:185130
Mir34a^tm1.1Lhe/Mir34a^tm1.1Lhe Mirc21^tm1.1Lhe/Mirc21^tm1.1Lhe involves: 129S4/SvJae * C57BL/6 * C57BL/6J	abnormal cell physiology	J:180692
	normal cellular phenotype	J:180692
Mir34a^tm1.1Pisc/Mir34a^tm1.1Pisc Mirc21^tm1.1Pisc/Mirc21^tm1.1Pisc Mirc34^tm1.1Pisc/Mirc34^tm1.1Pisc involves: 129S4/SvJae * C57BL/6 * C57BL/6J	abnormal efferent ductules of testis morphology	J:256929
	abnormal oviduct epithelium motile cilium morphology	J:256929
	abnormal oviduct physiology	J:256929
	abnormal oviduct transport	J:256929
	abnormal respiratory epithelium physiology	J:256929
	abnormal seminiferous tubule morphology	J:256929
	decreased respiratory motile cilia number	J:256929
	female infertility	J:256929
	increased susceptibility to bacterial infection induced morbidity/mortality	J:256929
	male infertility	J:256929
	nasal inflammation	J:256929
	normal neoplasm	J:256929
	normal nervous system phenotype	J:256929
	oligozoospermia	J:256929
	postnatal growth retardation	J:256929
	postnatal lethality, incomplete penetrance	J:256929
	normal renal/urinary system phenotype	J:256929
	slow postnatal weight gain	J:256929
Mirc21^tm1.1Aven/Mirc21^tm1.1Aven Mirc34^em1Jnch/Mirc34^em1Jnch involves: 129S4/SvJae * C57BL/6J	abnormal locomotor coordination	J:304721
	blepharoptosis	J:304721
	decreased body weight	J:304721
	decreased locomotor activity	J:304721
	hunched posture	J:304721
	jumpy	J:304721
	microphthalmia	J:304721
	postnatal growth retardation	J:304721
	postnatal lethality, incomplete penetrance	J:304721
	premature death	J:304721
Mirc21^tm1.1Kry/Mirc21^tm1.1Kry Satb2^tm1Rug/Satb2⁺ Tg(Col1a1-cre)1Kry/0 involves: 129S4/SvJaeSor * 129S6/SvEvTac * FVB/N	normal skeleton phenotype	J:185130

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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