Igs2 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Igs2
intergenic site 2
MGI:5461148

7 phenotypes from 7 alleles in 4 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Igs2^{em5(CAG-Mir802)Gpt}/Igs2^{em5(CAG-Mir802)Gpt} Tg(Ins2-cre)25Mgn/0 involves: C57BL/6JGpt * DBA	abnormal pancreatic beta cell differentiation	J:287584
	decreased circulating insulin level	J:287584
	decreased insulin secretion	J:287584
	decreased pancreatic beta cell mass	J:287584
	decreased pancreatic beta cell number	J:287584
	impaired glucose tolerance	J:287584
Igs2^{tm1(ACTB-EGFP,-tdTomato)Luo}/Igs2^{tm1(ACTB-EGFP,-tdTomato)Luo} involves: 129S1/Sv * 129X1/SvJ	no abnormal phenotype detected	J:166047
Igs2^{tm1(ACTB-EGFP,-tdTomato)Luo}/Igs2^{tm2(ACTB-tdTomato,-EGFP)Luo} involves: 129S1/Sv * 129X1/SvJ	no abnormal phenotype detected	J:166047
Igs2^{tm1(ACTB-EGFP,-tdTomato)Zng}/Igs2^{tm1(ACTB-EGFP,-tdTomato)Zng} involves: 129S1/Sv * 129X1/SvJ	no abnormal phenotype detected	J:202665
Igs2^{tm1(CAG-cas9)Mmw}/Igs2^{tm1(CAG-cas9)Mmw} involves: 129S1/Sv * 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:101977
Igs2^{tm1(CAG-mt-Keima)Fink}/Igs2^{tm1(CAG-mt-Keima)Fink} either: FVBNCrl.129(Cg)-Igs2^{tm1(CAG-mt-Keima)Fink} or (involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J * FVB/NCrl)	no abnormal phenotype detected	J:270139
Igs2^{tm2(ACTB-tdTomato,-EGFP)Luo}/Igs2^{tm2(ACTB-tdTomato,-EGFP)Luo} involves: 129S1/Sv * 129X1/SvJ	no abnormal phenotype detected	J:166047
Igs2^{tm2(ACTB-tdTomato,-EGFP)Zng}/Igs2^{tm2(ACTB-tdTomato,-EGFP)Zng} involves: 129S1/Sv * 129X1/SvJ	no abnormal phenotype detected	J:202665

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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