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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Igs2
intergenic site 2
MGI:5461148
19 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
Ctnnb1tm1Mmt/Ctnnb1+
Igs2tm1(CAG-Met)Zsu/Igs2+
Tg(Pbsn-cre)4Prb/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 * FVB/N 		increased prostate gland adenocarcinoma incidence J:284956
increased prostate intraepithelial neoplasia incidence J:284956
Igs2em1(Alb-Golm1)Jdon/Igs2+
involves: C57BL/6N 		decreased CD8-positive, alpha-beta T cell number J:306528
increased incidence of tumors by chemical induction J:306528
increased susceptibility to injury J:306528
Igs2em53(Myh6-cre/ERT2)Gpt/Igs2+
Stx17em1Gpt/Stx17em1Gpt
involves: C57BL/6JGpt 		abnormal cardiac muscle contractility J:345305
abnormal cardiovascular system physiology J:345305
abnormal heart morphology J:345305
abnormal myocardial fiber morphology J:345305
normal growth/size/body region phenotype J:345305
Igs2tm1(CAG-Met)Zsu/Igs2+
Ptentm1Hwu/Ptentm1Hwu
Tg(Pbsn-cre)4Prb/0
involves: 129 * C57BL/6 * DBA/2 * FVB/N 		increased carcinoma incidence J:268934
increased metastatic potential J:268934
increased prostate gland adenocarcinoma incidence J:268934
increased prostate gland tumor incidence J:268934
increased prostate intraepithelial neoplasia incidence J:268934
Igs2tm1(CAG-Met)Zsu/Igs2+
Tg(Pbsn-cre)4Prb/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2 * FVB/N 		normal endocrine/exocrine gland phenotype J:268934
increased prostate intraepithelial neoplasia incidence J:268934
Igs2tm1(CAG-mt-Keima)Fink/Igs2+
Lamp2tm1Psa/Lamp2tm1Psa
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ 		abnormal mitophagy J:253728
abnormal myocardial fiber physiology J:253728
Igs2tm1(CAG-mt-Keima)Fink/Igs2+
Kansl1em1.1Cya/Kansl1+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N 		abnormal mitophagy J:327464
Igs2tm1(CAG-Ptgs2os)Scrp/Igs2tm1(CAG-Ptgs2os)Scrp
involves: C57BL/6 		abnormal circulating cytokine level J:325487
increased circulating interleukin-10 level J:325487
Igs2tm1(CAG-Ptgs2os)Scrp/Igs2tm1(CAG-Ptgs2os)Scrp
Ptgs2osem1Scrp/Ptgs2osem1Scrp
involves: C57BL/6 		normal immune system phenotype J:325487
Kansl1em1Cya/Kansl1+
Tg(CAG-cre/Esr1*)5Amc/0
Igs2tm1(CAG-mt-Keima)Fink/Igs2+
Not Specified 		abnormal mitophagy J:327464
Kansl1em1Cya/Kansl1em1Cya
Tg(CAG-cre/Esr1*)5Amc/0
Igs2tm1(CAG-mt-Keima)Fink/Igs2+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * CBA * FVB/N 		abnormal mitophagy J:327464
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory