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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rr94
regulatory region 94
MGI:6833884
9 phenotypes from multigenic genotypes
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Allelic Composition
Genetic Background		 Annotated Term Reference
B2mtm1Jae/B2mtm1Jae
Rr94tm3.2Litt/Rr94tm3.2Litt
involves: 129P2/OlaHsd * 129S2/SvPas * FVB/N 		abnormal T cell differentiation J:158962
abnormal T cell subpopulation ratio J:158962
decreased CD4-positive, alpha-beta T cell number J:158962
increased CD8-positive, alpha-beta T cell number J:158962
increased T cell proliferation J:158962
Cbfbtm1Itan/Cbfbtm1Itan
Rr94tm3.1Litt/Rr94tm3.1Litt
Tg(Cd4-cre)1Cwi/0
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N 		abnormal double-positive T cell morphology J:158962
abnormal T cell subpopulation ratio J:158962
decreased CD4-positive, alpha-beta T cell number J:158962
decreased double-positive T cell number J:158962
increased CD8-positive, alpha-beta T cell number J:158962
increased double-positive T cell number J:158962
Rr94tm3.1Litt/Rr94+
Tg(Cd4-cre)1Cwi/0
Rr112tm4.1Litt/Rr112+
involves: 129P2/OlaHsd * 129S4/SvJaeSor * FVB/N 		abnormal T cell differentiation J:158962
abnormal T cell subpopulation ratio J:158962
decreased CD4-positive, alpha-beta T cell number J:158962
increased CD8-positive, alpha-beta T cell number J:158962
Rr94tm3.1Litt/Rr94+
Rr112tm4.1Litt/Rr112+
involves: 129P2/OlaHsd * 129S4/SvJaeSor * FVB/N 		normal immune system phenotype J:158962
Rr94tm3.2Litt/Rr94+
Rr112tm4.1Litt/Rr112+
involves: 129P2/OlaHsd * 129S4/SvJaeSor * FVB/N 		abnormal T cell differentiation J:158962
abnormal T cell subpopulation ratio J:158962
decreased CD4-positive, alpha-beta T cell number J:158962
increased CD8-positive, alpha-beta T cell number J:158962
Rr94tm3.2Litt/Rr94tm3.2Litt
H2-Ab1b-tm1Gru/H2-Ab1b-tm1Gru
involves: 129P2/OlaHsd * 129S2/SvPas * FVB/N 		abnormal T cell subpopulation ratio J:158962
decreased CD4-positive, alpha-beta T cell number J:158962
normal immune system phenotype J:158962
increased CD8-positive, alpha-beta T cell number J:158962
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory