Rr152 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rr152
regulatory region 152
MGI:6858039

14 phenotypes from 4 alleles in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rr152^tm2Cog/Igh⁺ involves: 129S2/SvPas * C57BL/6	decreased IgG1 level	J:90548
	decreased IgG2b level	J:90548
	decreased IgG3 level	J:90548
	decreased IgG level	J:90548
Rr152^tm2Cog/Rr152^tm2Cog involves: 129S2/SvPas * C57BL/6	decreased IgG1 level	J:90548
	decreased IgG2a level	J:90548
	decreased IgG2b level	J:90548
	decreased IgG3 level	J:90548
	decreased IgG level	J:90548
	increased pre-B cell number	J:90548
Rr152^tm3.1Cog/Rr152^tm3.1Cog involves: 129P2/OlaHsd * C57BL/6 * FVB/N	abnormal class switch recombination	J:71300
	decreased IgA level	J:71300
	decreased IgE level	J:71300
	decreased IgG2a level	J:71300
	decreased IgG2b level	J:71300
	decreased IgG3 level	J:71300
	decreased IgG level	J:71300
	decreased immunoglobulin level	J:71300
	normal immune system phenotype	J:71300
Rr152^tm3Cog/Rr152^tm3Cog involves: 129P2/OlaHsd * C57BL/6	abnormal B cell morphology	J:71300
	abnormal class switch recombination	J:71300
	decreased IgA level	J:71300
	decreased IgE level	J:71300
	decreased IgG1 level	J:71300
	decreased IgG2a level	J:71300
	decreased IgG2b level	J:71300
	decreased IgG3 level	J:71300
	decreased IgG level	J:71300
	decreased IgM level	J:71300
	decreased immunoglobulin level	J:71300
	normal immune system phenotype	J:71300
Rr152^tm5.1Cog/Rr152^tm5.1Cog involves: 129P2/OlaHsd * C57BL/6	abnormal class switch recombination	J:164513
	abnormal somatic hypermutation frequency	J:164513, J:333348
	decreased IgA level	J:164513
	decreased IgE level	J:164513
	decreased IgG2b level	J:164513
	decreased IgG3 level	J:164513
	decreased IgM level	J:164513

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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