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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Rr152
regulatory region 152
MGI:6858039
14 phenotypes from 4 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Rr152tm2Cog/Igh+
involves: 129S2/SvPas * C57BL/6 		decreased IgG1 level J:90548
decreased IgG2b level J:90548
decreased IgG3 level J:90548
decreased IgG level J:90548
Rr152tm2Cog/Rr152tm2Cog
involves: 129S2/SvPas * C57BL/6 		decreased IgG1 level J:90548
decreased IgG2a level J:90548
decreased IgG2b level J:90548
decreased IgG3 level J:90548
decreased IgG level J:90548
increased pre-B cell number J:90548
Rr152tm3.1Cog/Rr152tm3.1Cog
involves: 129P2/OlaHsd * C57BL/6 * FVB/N 		abnormal class switch recombination J:71300
decreased IgA level J:71300
decreased IgE level J:71300
decreased IgG2a level J:71300
decreased IgG2b level J:71300
decreased IgG3 level J:71300
decreased IgG level J:71300
decreased immunoglobulin level J:71300
normal immune system phenotype J:71300
Rr152tm3Cog/Rr152tm3Cog
involves: 129P2/OlaHsd * C57BL/6 		abnormal B cell morphology J:71300
abnormal class switch recombination J:71300
decreased IgA level J:71300
decreased IgE level J:71300
decreased IgG1 level J:71300
decreased IgG2a level J:71300
decreased IgG2b level J:71300
decreased IgG3 level J:71300
decreased IgG level J:71300
decreased IgM level J:71300
decreased immunoglobulin level J:71300
normal immune system phenotype J:71300
Rr152tm5.1Cog/Rr152tm5.1Cog
involves: 129P2/OlaHsd * C57BL/6 		abnormal class switch recombination J:164513
abnormal somatic hypermutation frequency J:164513, J:333348
decreased IgA level J:164513
decreased IgE level J:164513
decreased IgG2b level J:164513
decreased IgG3 level J:164513
decreased IgM level J:164513
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory