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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Dbnl
drebrin-like
MGI:700006
51 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
DbnlGt(betageo)11Byg/DbnlGt(betageo)11Byg
involves: 129P2/OlaHsd * C57BL/6 		abnormal T cell activation J:119847
abnormal T cell physiology J:119847
decreased body weight J:119847
decreased IgG1 level J:119847
decreased IgM level J:119847
decreased immunoglobulin level J:119847
decreased interleukin-2 secretion J:119847
decreased T cell proliferation J:119847
normal immune system phenotype J:119847
paresis J:119847
prenatal lethality, incomplete penetrance J:119847
normal reproductive system phenotype J:119847
tremors J:119847
Dbnltm1b(KOMP)Wtsi/Dbnltm1b(KOMP)Wtsi
C57BL/6N-Dbnltm1b(KOMP)Wtsi/Orl 		abnormal auditory brainstem response J:211773
abnormal optic disk morphology J:211773
abnormal retina blood vessel morphology J:211773
abnormal retina inner nuclear layer morphology J:211773
abnormal retina vasculature morphology J:211773
decreased circulating alkaline phosphatase level J:211773
decreased circulating cholesterol level J:211773
decreased circulating HDL cholesterol level J:211773
decreased circulating serum albumin level J:211773
decreased circulating total protein level J:211773
decreased circulating triglyceride level J:211773
decreased erythrocyte cell number J:211773
decreased hematocrit J:211773
decreased hemoglobin content J:211773
decreased locomotor activity J:211773
decreased total retina thickness J:211773
increased circulating glucose level J:211773
increased fluid intake J:211773
increased grip strength J:211773
increased heart weight J:211773
increased mean corpuscular hemoglobin J:211773
increased mean corpuscular volume J:211773
increased startle reflex J:211773
persistence of hyaloid vascular system J:211773
Dbnltm1Jwnd/Dbnl+
involves: BALB/c 		abnormal cardiovascular system physiology J:109363
convulsive seizures J:109363
decreased body weight J:109363
hindlimb paralysis J:109363
impaired coordination J:109363
impaired swimming J:109363
increased spleen weight J:109363
ruffled hair J:109363
tremors J:109363
Dbnltm1Jwnd/Dbnltm1Jwnd
involves: BALB/c 		abnormal cardiovascular system physiology J:109363
abnormal lung morphology J:109363
abnormal motor capabilities/coordination/movement J:109363
abnormal synaptic vesicle recycling J:109363
decreased body weight J:109363
emphysema J:109363
generalized edema J:109363
hindlimb paralysis J:109363
impaired coordination J:109363
increased spleen weight J:109363
limb grasping J:109363
respiratory distress J:109363
ruffled hair J:109363
tremors J:109363
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory