Rr253 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Rr253
regulatory region 253
MGI:7331605

25 phenotypes from 5 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Rr253^em1Kmm/Rr253^em1Kmm C57BL/6-Rr253^em1Kmm	abnormal class switch recombination	J:316113
	abnormal effector T cell number	J:316113
	abnormal peritoneal macrophage morphology	J:316113
	abnormal spleen B cell follicle morphology	J:316113
	decreased B cell number	J:316113
	decreased mature NK cell number	J:316113
	decreased monocyte cell number	J:316113
	decreased plasmacytoid dendritic cell number	J:316113
	decreased spleen B cell follicle number	J:316113
	decreased spleen B cell follicle size	J:316113
	normal embryo phenotype	J:316113
	normal hematopoietic system phenotype	J:316113
	increased dendritic cell number	J:316113
	increased lymphocyte cell number	J:316113
	increased neutrophil cell number	J:316113
	increased NK cell number	J:316113
	increased susceptibility to viral infection induced morbidity/mortality	J:316113
	increased T cell number	J:316113
	spleen hypoplasia	J:316113
Rr253^em3Kmm/Rr253^em3Kmm C57BL/6J-Rr253^em3Kmm	decreased dendritic cell number	J:334296
Rr253^em4Kmm/Rr253^em4Kmm C57BL/6J-Rr253^em4Kmm	normal hematopoietic system phenotype	J:334296
Rr253^em4Kmm/Rr253^em4Kmm C57BL/6J-Rr253^em4Kmm	normal immune system phenotype	J:334296
Rr253^em5Kmm/Rr253^em5Kmm C57BL/6J-Rr253^em5Kmm	decreased dendritic cell number	J:334296
Rr253^em5Kmm/Rr253^em5Kmm C57BL/6J-Rr253^em5Kmm	increased dendritic cell number	J:334296
Rr253^em6Kmm/Rr253^em6Kmm C57BL/6J-Rr253^em6Kmm	abnormal common myeloid progenitor cell morphology	J:334296
	abnormal T-helper 2 physiology	J:334296
	decreased dendritic cell number	J:334296
	decreased granulocyte monocyte progenitor cell number	J:334296
	decreased monocyte cell number	J:334296
	decreased plasmacytoid dendritic cell number	J:334296
	normal hematopoietic system phenotype	J:334296
	normal immune system phenotype	J:334296
	increased dendritic cell number	J:334296
	increased susceptibility to parasitic infection induced morbidity/mortality	J:334296

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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