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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Acp2
acid phosphatase 2, lysosomal
MGI:87882
44 phenotypes from 3 alleles in 3 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Acp2nax/Acp2nax
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal cerebellar molecular layer J:95958
abnormal cerebellar Purkinje cell layer J:95958
abnormal cerebellum morphology J:95958
abnormal CNS glial cell morphology J:95958
abnormal dermal layer morphology J:95958
abnormal epidermis stratum basale morphology J:95958
abnormal hair follicle morphology J:95958
abnormal Purkinje cell dendrite morphology J:95958
absent cerebellar granule layer J:95958
alopecia J:95958
ataxia J:95958
decreased body height J:95958
decreased body weight J:95958
delayed hair appearance J:95958
ectopic Purkinje cell J:95958
postnatal growth retardation J:95958
small cerebellum J:95958
thin external granule cell layer J:95958
thin hair shaft J:95958
tremors J:95958
Acp2tm1a(EUCOMM)Wtsi/Acp2tm1a(EUCOMM)Wtsi
C57BL/6N-Acp2tm1a(EUCOMM)Wtsi/H 		abnormal behavior J:165965
abnormal bone mineralization J:165965
abnormal bone structure J:165965
decreased body weight J:165965
decreased bone mineral density J:165965
decreased CD4-positive, alpha-beta T cell number J:165965
decreased CD8-positive, alpha-beta T cell number J:165965
decreased erythrocyte cell number J:165965
decreased T cell number J:165965
increased B cell number J:165965
Acp2tm1Psa/Acp2tm1Psa
involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6J 		abnormal compact bone morphology J:41986
abnormal lysosome morphology J:41986
abnormal microglial cell morphology J:41986
abnormal vertebral body morphology J:41986
abnormal vertebral column morphology J:41986
abnormal vertebral pedicle morphology J:41986
accumulation of giant lysosomes in kidney/renal tubule cells J:41986
astrocytosis J:41986
normal behavior/neurological phenotype J:41986
decreased bone mineralization J:41986
increased trabecular bone connectivity density J:41986
kyphoscoliosis J:41986
kyphosis J:41986
lordosis J:41986
tonic-clonic seizures J:41986
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory