Chrna1 Phenotype Annotations

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Chrna1
cholinergic receptor nicotinic alpha 1 subunit
MGI:87885

9 phenotypes from 2 alleles in 2 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Chrna1^{tm1b(EUCOMM)Hmgu}/Chrna1^{tm1b(EUCOMM)Hmgu} C57BL/6N-Chrna1^{tm1b(EUCOMM)Hmgu}/Ics	preweaning lethality, complete penetrance	J:211773
Chrna1^tm1Klee/Chrna1^tm1Klee involves: 129S4/SvJae * C57BL/6	abnormal endplate potential	J:161300
	abnormal innervation pattern to muscle	J:161300
	abnormal miniature endplate potential	J:161300
	abnormal neuromuscular synapse morphology	J:161300
	carpoptosis	J:161300
	increased motor neuron number	J:161300
	kyphosis	J:161300
	neonatal lethality	J:161300

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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