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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Actb
actin, beta
MGI:87904
18 phenotypes from 9 alleles in 10 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Actbem1Erv/Actbem1Erv
involves: C57BL/6 		abnormal outer hair cell stereociliary bundle morphology J:265862
decreased outer hair cell stereocilia number J:265862
impaired hearing J:265862
increased susceptibility to age-related hearing loss J:265862
normal muscle phenotype J:265862
short outer hair cell stereocilia J:265862
Actbtm1.1Erv/Actbtm1.1Erv
Foxg1tm1(cre)Skm/Foxg1+
involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * FVB/N 		normal hearing/vestibular/ear phenotype J:167543
postnatal lethality, incomplete penetrance J:167543
Actbtm1.1Erv/Actbtm1.1Erv
Tg(Atoh1-cre)1Bfri/?
involves: 129S6/SvEvTac * C57BL/6 * CBA * FVB/N 		abnormal cochlear hair cell stereociliary bundle morphology J:167543
normal hearing/vestibular/ear phenotype J:167543
increased or absent threshold for auditory brainstem response J:167543
increased susceptibility to age-related hearing loss J:167543
short cochlear hair cell stereocilia J:167543
Actbtm1Alj/Actbtm1Alj
involves: 129S1/Sv * 129X1/SvJ * CD-1 		prenatal lethality, complete penetrance J:67904
Actbtm1Bhr/Actbtm1Bhr
involves: 129S7/SvEvBrd * C57BL/6 		embryonic growth retardation J:46634
embryonic lethality during organogenesis, complete penetrance J:46634
Actbtm1Dost/Actbtm1Dost
involves: 129P2/OlaHsd * C57BL/6 		embryonic lethality at implantation, complete penetrance J:136574
Actbtm1Itl/Actbtm1Itl
involves: 129S/SvEv 		no abnormal phenotype detected J:187804
Actbtm1Npa/Actb+
involves: BALB/cJ 		decreased body weight J:129639
Actbtm1Npa/Actbtm1Npa
involves: BALB/cJ 		embryonic lethality during organogenesis, complete penetrance J:129639
Actbtm2Npa/Actb+
involves: BALB/c 		decreased body size J:129105
Tg(KRT14-EGFP/Actb)50Efu/0
Not Specified 		no abnormal phenotype detected J:156846
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory