Acvr2b Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Acvr2b
activin receptor IIB
MGI:87912

21 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Acvr2a^tm1Hsch/Acvr2a⁺ Acvr2b^tm1Enl/Acvr2b^tm1Enl involves: 129S1/Sv * 129S4/SvJae * C57BL/6J	perinatal lethality, complete penetrance	J:57262
Acvr2a^tm1Hsch/Acvr2a⁺ Acvr2b^tm1Spo/Acvr2b^tm1Spo involves: 129S1/Sv * 129S4/SvJae	abnormal left-right axis patterning	J:114533
	lumbar vertebral transformation	J:114533
	right pulmonary isomerism	J:114533
	transposition of great arteries	J:114533
Acvr2a^tm1Hsch/Acvr2a⁺ Acvr2b^tm1.1Spo/Acvr2b^tm1.1Spo involves: 129S1/Sv * 129S4/SvJae * FVB/N	abnormal left-right axis patterning	J:114533
	lumbar vertebral transformation	J:114533
	right pulmonary isomerism	J:114533
	transposition of great arteries	J:114533
Acvr2a^tm1Hsch/Acvr2a^tm1Hsch Acvr2b^tm1.1Spo/Acvr2b^tm1.1Spo involves: 129S1/Sv * 129S4/SvJae * FVB/N	abnormal embryonic tissue morphology	J:114533
	embryonic growth arrest	J:114533
	embryonic lethality between somite formation and embryo turning	J:114533
	embryonic-extraembryonic boundary constriction	J:114533
Acvr2a^tm1Hsch/Acvr2a^tm1Hsch Acvr2b^tm1Enl/Acvr2b⁺ involves: 129S1/Sv * 129S4/SvJae * C57BL/6J	abnormal gastrulation	J:57262
	abnormal mesoderm development	J:57262
	abnormal primitive streak elongation	J:57262
	abnormal rostral-caudal axis patterning	J:57262
	absent allantois	J:57262
	absent amnion	J:57262
	absent head fold	J:57262
	absent heart tube	J:57262
	embryonic growth arrest	J:57262
	embryonic lethality between implantation and somite formation, complete penetrance	J:57262
	embryonic-extraembryonic boundary constriction	J:57262
Acvr2a^tm1Hsch/Acvr2a^tm1Hsch Acvr2b^tm1Enl/Acvr2b^tm1Enl involves: 129S1/Sv * 129S4/SvJae * C57BL/6J	absent mesoderm	J:57262
	embryonic growth arrest	J:57262
	embryonic lethality between implantation and somite formation, complete penetrance	J:57262
	embryonic-extraembryonic boundary constriction	J:57262
	failure to gastrulate	J:57262
	increased embryonic epiblast cell apoptosis	J:57262

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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