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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ada
adenosine deaminase
MGI:87916
64 phenotypes from 4 alleles in 4 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Adatm1Mw/Adatm1Mw
involves: 129S7/SvEvBrd 		abnormal dendritic cell physiology J:138722
abnormal lung vasculature morphology J:231559
abnormal placenta morphology J:234143
abnormal placenta vasculature J:234143
abnormal pulmonary alveolar system morphology J:231559
abnormal pulmonary gas exchange J:231559
decreased lung compliance J:231559
decreased placenta weight J:234143
heart right ventricle hypertrophy J:231559
increased airway resistance J:231559
increased dendritic cell number J:138722
increased lung elastance J:231559
increased right ventricle systolic pressure J:231559
increased vascular smooth muscle cell proliferation J:231559
maternal effect J:234143
pulmonary hypertension J:231559
small placenta J:234143
vascular smooth muscle hypertrophy J:231559
Adatm1Mw/Adatm1Mw
involves: 129S7/SvEvBrd * C57BL/6 		abnormal enzyme/coenzyme level J:25085
abnormal hepatocyte morphology J:25085
abnormal liver morphology J:25085
abnormal nucleotide metabolism J:25085
cyanosis J:25085
decreased body weight J:25085
decreased circulating serum albumin level J:25085
decreased circulating total protein level J:25085
decreased hepatocyte number J:25085
decreased T cell number J:25085
hepatic necrosis J:25085
increased hepatocyte karyomegaly J:25085
neonatal lethality, complete penetrance J:25085
small liver J:25085
Adatm1Mw/Adatm1Mw
involves: 129S7/SvEvBrd * C57BL/6 * FVB/N 		abnormal penile erection J:135978
priapism J:135978
Adatm1Mw/Adatm1Mw
Tg(PLADA)4118Rkmb/0
involves: 129S7/SvEvBrd * C57BL/6 		abnormal costochondral joint morphology J:73418
abnormal renal glomerulus morphology J:73418
abnormal renal tubule morphology J:73418
abnormal rib morphology J:73418
abnormal spleen red pulp morphology J:73418
abnormal thymus corticomedullary boundary morphology J:73418
anemia J:73418
normal cardiovascular system phenotype J:234143
decreased double-positive T cell number J:73418
decreased immunoglobulin level J:73418
decreased leukocyte cell number J:73418
normal embryo phenotype J:234143
increased double-negative T cell number J:73418
increased eosinophil cell number J:73418
increased granulocyte number J:73418
increased macrophage cell number J:73418
lung inflammation J:73418
postnatal lethality, complete penetrance J:73418, J:234143
normal renal/urinary system phenotype J:234143
small spleen J:73418
small thymus J:73418
spleen hypoplasia J:73418
tachypnea J:73418
Adatm1Mw/Adatm1Mw
Tg(PLFSADA)2465Rkmb/0
involves: 129S7/SvEvBrd * C57BL/6 * FVB/N 		no abnormal phenotype detected J:29350
Adatm1Vlr/Adatm1Vlr
either: 129P2/OlaHsd-Adatm1Vlr or (involves: (129P2/OlaHsd * FVB/N) 		abnormal pulmonary alveolus morphology J:26731
abnormal small intestine morphology J:26731
atelectasis J:26731
cyanosis J:26731
extramedullary hematopoiesis J:26731
hepatic necrosis J:26731
intrahepatic cholestasis J:26731
neonatal lethality, incomplete penetrance J:26731
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory