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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Adra2a
adrenergic receptor, alpha 2a
MGI:87934
16 phenotypes from 6 alleles in 8 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Adra2am1Btlr/Adra2am1Btlr
C57BL/6J-Adra2am1Btlr 		decreased circulating glucose level J:267700
increased circulating insulin level J:267700
Adra2am2Btlr/Adra2am2Btlr
C57BL/6J-Adra2am2Btlr 		decreased circulating glucose level J:267701
Adra2atm1.1(KOMP)Vlcg/Adra2atm1.1(KOMP)Vlcg
C57BL/6N-Adra2atm1.1(KOMP)Vlcg/Ucd 		abnormal testis morphology J:211773
decreased fasting circulating glucose level J:211773
decreased prepulse inhibition J:211773
decreased startle reflex J:211773
hyperactivity J:211773
improved glucose tolerance J:211773
small testis J:211773
Adra2atm1Bkk/Adra2atm1Bkk
involves: 129S1/Sv * 129X1/SvJ 		abnormal glucose homeostasis J:130781
hypoglycemia J:130781
Adra2atm1Bkk/Adra2atm1Bkk
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal synaptic norepinephrine release J:58591
abnormal systemic arterial blood pressure J:76317
increased heart rate J:76317
Adra2atm1Bkk/Adra2atm1Bkk
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J 		abnormal spike wave discharge J:197965
Adra2atm1Lel/Adra2atm1Lel
involves: 129S2/SvPas * C57BL/6 		abnormal systemic arterial blood pressure J:34820
Adra2atm1Qiwa/Adra2atm1Qiwa
B6.129-Adra2atm1Qiwa 		no abnormal phenotype detected J:149752
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory