Adrb2 Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Adrb2
adrenergic receptor, beta 2
MGI:87938

24 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Adipoq^tm1Ish/Adipoq^tm1Ish Adrb2^tm1Kry/Adrb2^tm1Kry Tg(Col1a1-cre)1Kry/0 involves: 129S7/SvEvBrd * C57BL/6J * FVB	increased bone mass	J:199264
Adrb1^tm1Bkk/Adrb1^tm1Bkk Adrb2^tm1Bkk/Adrb2^tm1Bkk involves: 129S1/Sv * 129X1/SvJ	normal skeleton phenotype	J:97566
Adrb1^tm1Bkk/Adrb1^tm1Bkk Adrb2^tm1Bkk/Adrb2^tm1Bkk involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2 * FVB/N	abnormal cardiovascular system physiology	J:55553
	abnormal physiological response to xenobiotic	J:55553
	abnormal response/metabolism to endogenous compounds	J:55553
	decreased cardiac muscle contractility	J:55553
	decreased heart rate	J:55553
	decreased oxygen consumption	J:55553
Adrb1^tm1Bkk/Adrb1^tm1Bkk Adrb2^tm1Bkk/Adrb2^tm1Bkk Adrb3^tm1Lowl/Adrb3^tm1Lowl involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2 * FVB/N	abnormal brown adipose tissue morphology	J:79309
	decreased oxygen consumption	J:79309
	normal endocrine/exocrine gland phenotype	J:79309
	impaired adaptive thermogenesis	J:79309
	increased body weight	J:79309
	increased brown fat cell size	J:79309
	increased circulating leptin level	J:79309
	increased interscapular fat pad weight	J:79309
	increased total body fat amount	J:79309
	obese	J:79309
Adrb2^tm1Kry/Adrb2⁺ Lep^ob/Lep⁺ Tg(Col1a1-cre)1Kry/0 involves: C57BL/6 * C57BL/10J * FVB	decreased circulating glucose level	J:145998
	increased circulating insulin level	J:145998
Or8a1^{tm14(Adrb2)Mom}/Or8a1^{tm14(Adrb2)Mom} involves: 129P2/OlaHsd * C57BL/6	normal nervous system phenotype	J:91160
Or8a1^tm17Mom/Or8a1^tm17Mom involves: 129P2/OlaHsd * C57BL/6	abnormal axon extension	J:91160
	abnormal neuron morphology	J:91160
	abnormal olfactory bulb development	J:91160
Or8a1^{tm35(Adrb2)Mom}/Or8a1^{tm35(Adrb2)Mom} B6;129P2-Or8a1^{tm35(Adrb2)Mom}/MomJ	abnormal olfactory bulb development	J:203525
	abnormal olfactory receptor morphology	J:203525

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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