Agrn Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Agrn
agrin
MGI:87961

35 phenotypes from 8 alleles in 12 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Agrn^Gt(Ex192)Byg/Agrn^Gt(Ex192)Byg involves: 129P2/OlaHsd * C57BL/6	abnormal neuromuscular synapse morphology	J:70273
	neonatal lethality, complete penetrance	J:70273
	normal renal/urinary system phenotype	J:122821
Agrn^nmf380/Agrn^nmf380 C57BL/6J-Agrn^nmf380/J	abnormal hindlimb morphology	J:176117
	abnormal motor capabilities/coordination/movement	J:176117
	abnormal neuromuscular synapse morphology	J:176117
	abnormal skeletal muscle fiber type ratio	J:176117
	camptodactyly	J:87349
	decreased body size	J:87349, J:176117
	impaired limb coordination	J:87349
	limb grasping	J:87349
	muscle spasm	J:87349
	myopathy	J:87349
	normal nervous system phenotype	J:176117
	paraparesis	J:87349
	premature death	J:176117
	skeletal muscle atrophy	J:176117
	tremors	J:87349
Agrn^nmf380/Agrn^nmf380 involves: BALB/c * C57BL/6J	abnormal neuromuscular synapse morphology	J:176117
Agrn^nmf380/Agrn^nmf380 involves: BALB/c * C57BL/6J	premature death	J:176117
Agrn^nmf380/Agrn^nmf380 involves: C57BL/6J * CAST	abnormal neuromuscular synapse morphology	J:176117
	normal mortality/aging	J:176117
	normal muscle phenotype	J:176117
Agrn^nmf380/Agrn^nmf380 involves: C57BL/6J * DBA	abnormal neuromuscular synapse morphology	J:176117
	premature death	J:176117
	skeletal muscle atrophy	J:176117
Agrn^nmf380/Agrn^nmf380 involves: C57BL/6J * FVB/N	abnormal neuromuscular synapse morphology	J:176117
Agrn^nmf380/Agrn^nmf380 involves: C57BL/6J * FVB/N	premature death	J:176117
Agrn^tm1Jrs/Agrn^tm1Jrs involves: 129S1/Sv * 129X1/SvJ	abnormal axon morphology	J:33098
	abnormal innervation	J:33098
	abnormal innervation pattern to muscle	J:33098
	abnormal neuromuscular synapse morphology	J:33098
	abnormal paired-pulse inhibition	J:79028
	decreased CNS synapse formation	J:79028
	increased post-tetanic potentiation	J:79028
	perinatal lethality, complete penetrance	J:33098
Agrn^tm1Jrs/Agrn^tm1Jrs involves: 129S1/Sv * 129X1/SvJ * C57BL/6	neonatal lethality	J:55407
	normal nervous system phenotype	J:55407
Agrn^tm1Rwb/Agrn^tm1Rwb Tg(NPHS2-cre)295Lbh/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal renal glomerulus basement membrane morphology	J:122821
	increased renal glomerulus basement membrane thickness	J:122821
	normal renal/urinary system phenotype	J:122821
Agrn^tm1Rwb/Agrn^tm1Rwb Tg(Pax3-cre)1Joe/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal diaphragm morphology	J:122821
	abnormal neuromuscular synapse morphology	J:122821
	perinatal lethality, complete penetrance	J:122821
Agrn^tm1Rwb/Agrn^tm1Rwb Tg(Tek-cre)1Ywa/? involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL	abnormal blood vessel morphology	J:220073
	normal nervous system phenotype	J:220073
Agrn^tm2Jrs/Agrn^tm2Jrs involves: 129S1/Sv * 129X1/SvJ * C57BL/6	no abnormal phenotype detected	J:55407
Agrn^tm3Jrs/Agrn^tm3Jrs involves: 129S1/Sv * 129X1/SvJ * C57BL/6	abnormal innervation	J:55407
	abnormal neuromuscular synapse morphology	J:55407
	no spontaneous movement	J:55407
	perinatal lethality, complete penetrance	J:55407
	primary atelectasis	J:55407
Agrn^tm4Jrs/Agrn^tm4Jrs involves: 129 * C57BL/6	normal renal/urinary system phenotype	J:122821
Agrn^tm4Jrs/Agrn^tm4Jrs Not Specified	failure of neuromuscular synapse presynaptic differentiation	J:161300
Agrn^tm5Jrs/Agrn^tm5Jrs involves: 129S1/Sv * 129X1/SvJ * FVB/N	normal mortality/aging	J:220073
	normal nervous system phenotype	J:220073

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