Alb Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Alb
albumin
MGI:87991

81 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Alb^em12Mvw/Alb^em12Mvw Fcgrt^tm1Dcr/Fcgrt^tm1Dcr Tg(FCGRT)32Dcr/Tg(FCGRT)32Dcr B6.Cg-Tg(FCGRT)32Dcr Alb^em12Mvw Fcgrt^tm1Dcr/MvwJ	decreased circulating serum albumin level	J:101977
Alb^{tm1(cre/ERT2)Mtz}/Alb⁺ Kras^tm4Tyj/Kras⁺ Pten^tm2Mak/Pten^tm2Mak involves: 129P2/OlaHsd * 129S2/SvPas * 129S4/SvJae	increased cholangiocarcinoma incidence	J:254370
	increased hepatocellular carcinoma incidence	J:254370
Alb^{tm1(cre/ERT2)Mtz}/Alb⁺ Gt(ROSA)26Sor^{tm1(Notch1)Dam}/Gt(ROSA)26Sor⁺ involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6	increased cholangiocarcinoma incidence	J:192740
Alb^{tm1(cre/ERT2)Mtz}/Alb⁺ Per2^tm1Jt/Per2⁺ Smg6^tm1.1Tac/Smg6^tm1.1Tac involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6J	abnormal circadian behavior phase	J:342742
	abnormal circardian behavior entrainment	J:342742
	abnormal locomotor circadian rhythm	J:342742
	prolonged circadian behavior period	J:342742
Alb^{tm1(cre/ERT2)Mtz}/Alb⁺ Nr5a2^tm1Sjns/Nr5a2^tm1Sjns involves: 129/Sv * 129S2/SvPas * C57BL/6 * SJL	abnormal bile salt level	J:129068
	abnormal feces composition	J:129068
	abnormal feces lipid level	J:129068
	abnormal intestinal lipid absorption	J:129068
	increased feces bile salt level	J:129068
Alb^{tm1(cre/ERT2)Mtz}/Alb⁺ Hes1^tm1Kag/Hes1^tm1Kag involves: 129S2/SvPas * C57BL/6 * CBA	normal neoplasm	J:192740
Alb^{tm1(cre/ERT2)Mtz}/Alb⁺ Fth1^tm1.1Lck/Fth1^tm1.1Lck involves: 129/Sv * C57BL/6 * SJL	abnormal liver iron level	J:166515
	normal liver/biliary system phenotype	J:166515
Alb^{tm1(cre/ERT2)Mtz}/Alb⁺ Hcfc1^tm1Lwh/Hcfc1⁺ involves: 129S2/SvPas * C57BL/6	impaired liver regeneration	J:231596
Alb^{tm1(cre/ERT2)Mtz}/Alb⁺ Polr2m^tm1.1Rgr/Polr2m^tm1.1Rgr Trp53^tm1Tyj/Trp53^tm1Tyj involves: 129S2/SvPas * C57BL/6	increased hepatocyte karyomegaly	J:291184
	increased hepatocyte proliferation	J:291184
Alb^{tm1(cre/ERT2)Mtz}/Alb^{tm1(cre/ERT2)Mtz} Slc2a2^tm2Thor/Slc2a2^tm2Thor involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6	abnormal bile salt level	J:197607
	abnormal circulating glucose level	J:197607
	abnormal glucose homeostasis	J:197607
	abnormal glycogen homeostasis	J:197607
	abnormal lipid homeostasis	J:197607
	decreased cellular glucose uptake	J:197607
	decreased insulin secretion	J:197607
	decreased liver cholesterol level	J:197607
	decreased liver triglyceride level	J:197607
	normal homeostasis/metabolism phenotype	J:197607
	impaired glucose tolerance	J:197607
	increased liver glycogen level	J:197607
	increased skeletal muscle cell glucose uptake	J:197607
G6pc1^tm1.1Ics/G6pc1^tm1.1Ics Alb^{tm1(cre/ERT2)Mtz}/Alb⁺ involves: 129S2/SvPas * C57BL/6J	abnormal blood homeostasis	J:195257
	abnormal hepatocyte morphology	J:195257
	enlarged liver	J:195257
	hepatic steatosis	J:195257
	normal homeostasis/metabolism phenotype	J:195257
	increased blood uric acid level	J:195257
	increased circulating cholesterol level	J:195257
	increased circulating triglyceride level	J:195257
	increased liver adenoma incidence	J:195257
	increased liver glycogen level	J:195257
	increased liver triglyceride level	J:195257
	increased liver weight	J:195257
	pale liver	J:195257
Gt(ROSA)26Sor^{tm2(OVA/EGFP)Dwir}/Gt(ROSA)26Sor⁺ Alb^{tm1(cre/ERT2)Mtz}/Alb⁺ involves: 129P2/OlaHsd * 129S2/SvPas	abnormal hepatocyte physiology	J:173806
Gt(ROSA)26Sor^{tm2(OVA/EGFP)Dwir}/Gt(ROSA)26Sor⁺ Tg(TcraTcrb)1100Mjb/0 Alb^{tm1(cre/ERT2)Mtz}/Alb⁺ involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6	increased circulating alanine transaminase level	J:173806
Mir32^em1Gpt/Mir32^em1Gpt Alb^em1(icre)Gpt/Alb⁺ C57BL/6JGpt-Mir32^em1Gpt Alb^em1(icre)Gpt	abnormal lipid metabolism	J:344660
	abnormal liver physiology	J:344660
	normal behavior/neurological phenotype	J:344660
	decreased circulating alanine transaminase level	J:344660
	decreased circulating aspartate transaminase level	J:344660
	decreased circulating cholesterol level	J:344660
	decreased circulating LDL cholesterol level	J:344660
	decreased endoplasmic reticulum stress	J:344660
	decreased liver cholesterol level	J:344660
	decreased liver triglyceride level	J:344660
	decreased liver weight	J:344660
	decreased susceptibility to diet-induced hepatic steatosis	J:344660
	normal growth/size/body region phenotype	J:344660
	normal homeostasis/metabolism phenotype	J:344660
	improved glucose tolerance	J:344660
	increased insulin sensitivity	J:344660
Mob1a^tm1.1Asuz/Mob1a^tm1.1Asuz Mob1b^{Gt(CC0690)Wtsi}/Mob1b^{Gt(CC0690)Wtsi} Alb^{tm1(cre/ERT2)Mtz}/Alb⁺ involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6	increased hepatobiliary system tumor incidence	J:228499
Orc1^tm1.1Gle/Orc1^tm1.1Gle Alb^{tm1(cre/ERT2)Mtz}/Alb⁺ involves: 129S2/SvPas * C57BL/6 * SJL	normal cellular phenotype	J:272584
	decreased hepatocyte number	J:272584
	increased hepatocyte karyomegaly	J:272584
	normal liver/biliary system phenotype	J:272584
	polyploidy	J:272584
Slc2a9^tm1.1Thor/Slc2a9⁺ Alb^{tm1(cre/ERT2)Mtz}/Alb⁺ involves: 129S2/SvPas * C57BL/6 * C57BL/6N	increased urine magnesium level	J:153089
	increased urine phosphate level	J:153089
Slc2a9^tm1.1Thor/Slc2a9^tm1.1Thor Alb^{tm1(cre/ERT2)Mtz}/Alb⁺ involves: 129S2/SvPas * C57BL/6 * C57BL/6N	decreased urine osmolality	J:153089
	decreased urine pH	J:153089
	increased blood uric acid level	J:153089
	increased urine magnesium level	J:153089
	increased urine phosphate level	J:153089
	increased urine potassium level	J:153089
	polyuria	J:153089
	normal renal/urinary system phenotype	J:153089
	uraturia	J:153089
Uri1^tm1.1Ndj/Uri1⁺ Alb^{tm1(cre/ERT2)Mtz}/Alb⁺ B6.Cg-Alb^{tm1(cre/ERT2)Mtz} Uri1^tm1.1Ndj	abnormal enzyme/coenzyme level	J:217463
	decreased incidence of tumors by chemical induction	J:217463
	decreased susceptibility to injury	J:217463
Uri1^tm1.1Ndj/Uri1^tm1.1Ndj Alb^{tm1(cre/ERT2)Mtz}/Alb⁺ B6.Cg-Alb^{tm1(cre/ERT2)Mtz} Uri1^tm1.1Ndj	abnormal liver morphology	J:217463
	hepatic necrosis	J:217463
	increased circulating alanine transaminase level	J:217463
	increased hepatocyte apoptosis	J:217463
	liver failure	J:217463
	liver hemorrhage	J:217463
	liver inflammation	J:217463
	postnatal lethality	J:217463
Ywhab^em1Gpt/Ywhab^em1Gpt Alb^em1(icre)Gpt/Alb⁺ C57BL/6JGpt-Ywhab^em1Gpt Alb^em1(icre)Gpt	decreased liver glycogen level	J:323777
	enhanced gluconeogenesis	J:323777
	impaired glucose tolerance	J:323777
	increased circulating glucose level	J:323777

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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