Apc Phenotype Annotations - Multigenic Genotypes

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Apc
APC, WNT signaling pathway regulator
MGI:88039

157 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apc^Min/Apc⁺ Dnmt1^tm1Jae/Dnmt1⁺ involves: 129S4/SvJae * C57BL/6J	intestine polyps	J:75230
Apc^Min/Apc⁺ Dnmt1^tm1Jae/Dnmt1^tm1Pwl involves: 129S4/SvJae * C57BL/6J	normal digestive/alimentary phenotype	J:75230
Apc^Min/Apc⁺ Il6^tm1Kopf/Il6^tm1Kopf involves: 129S2/SvPas * C57BL/6	abnormal tumor incidence	J:130429
	normal adipose tissue phenotype	J:130429
	normal muscle phenotype	J:130429
Apc^Min/Apc⁺ Nos2^tm1Lau/Nos2⁺ B6.Cg-Nos2^tm1Lau Apc^Min	decreased tumor growth/size	J:73152
Apc^Min/Apc⁺ Nos2^tm1Lau/Nos2⁺ B6.Cg-Nos2^tm1Lau Apc^Min	decreased tumor incidence	J:73152
Apc^Min/Apc⁺ Nos2^tm1Lau/Nos2^tm1Lau B6.Cg-Nos2^tm1Lau Apc^Min	decreased tumor growth/size	J:73152
	decreased tumor incidence	J:73152
Apc^Min/Apc⁺ Ptgs1^tm1Unc/Ptgs1⁺ involves: 129P2/OlaHsd * C57BL/6J	decreased tumor incidence	J:64401
	intestine polyps	J:64401
	premature death	J:64401
Apc^Min/Apc⁺ Ptgs1^tm1Unc/Ptgs1^tm1Unc involves: 129P2/OlaHsd * C57BL/6J	decreased prostaglandin level	J:64401
	decreased tumor incidence	J:64401
	intestine polyps	J:64401
	normal mortality/aging	J:64401
Apc^Min/Apc⁺ Pla2g2a^Mom1-r/Pla2g2a⁺ either: (AKR/J x C57BL/6J-Apc^Min)F1 or (MA/MyJ x C57BL/6J-Apc^Min)F1 or (CAST/EiJ x C57BL/6J-Apc^Min)F1	decreased alimentary system tumor incidence	J:15703
	decreased intestinal adenoma incidence	J:15703
Apc^Min/Apc⁺ Pla2g2a^Mom1-r/? Prkdc^dxnph/Prkdc^dxnph involves: BALB/cByJ * C57BL/6	increased incidence of tumors by ionizing radiation induction	J:83497
Apc^Min/Apc⁺ Mmp7^tm1Lmm/Mmp7^tm1Lmm involves: C57BL/6 * C57BL/6J	abnormal tumor morphology	J:38609
	increased tumor incidence	J:38609
Apc^Min/Apc⁺ Msh2^tm1Mak/Msh2⁺ Nos2^tm1Mrl/Nos2^tm1Mrl involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J	intestine polyps	J:200824
Apc^Min/Apc⁺ Msh2^tm1Mak/Msh2^tm1Mak involves: 129P2/OlaHsd * C57BL/6J	anemia	J:75393
	increased intestinal adenoma incidence	J:75393
	intestinal obstruction	J:75393
	intestine polyps	J:200824
	premature death	J:75393
Apc^Min/Apc⁺ Msh2^tm1Mak/Msh2^tm1Mak Nos2^tm1Mrl/Nos2^tm1Mrl involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J	intestine polyps	J:200824
Apc^Min/Apc⁺ Pms2^tm1Lisk/Pms2^tm1Lisk involves: 129S2/SvPas * C57BL/6J	increased intestinal adenoma incidence	J:46419
	intestine polyps	J:46419
	premature death	J:46419
Apc^Min/Apc⁺ Trp53^tm1Mlh/Trp53^tm1Mlh involves: 129P2/OlaHsd * C57BL/6 * SWR	abnormal exocrine pancreas morphology	J:29664
	increased pancreatic acinar cell carcinoma incidence	J:29664
Apc^Min/Apc⁺ Msh2^tm1Htr/Msh2^tm1Htr involves: 129P2/OlaHsd * BALB/c * C57BL/6J	increased gastrointestinal tumor incidence	J:45433
	premature death	J:45433
Apc^Min/Apc⁺ Ppard^tm1Jps/Ppard^tm1Jps involves: 129/Sv * AKR/J * C57BL/6 * C57BL/6J	increased intestinal adenocarcinoma incidence	J:90337
	intestine polyps	J:90337
Apc^Min/Apc⁺ Gt(ROSA)26Sor/Gt(ROSA)26Sor⁺ B6.Cg-Gt(ROSA)26Sor Apc^Min	abnormal tumor susceptibility	J:66060
	decreased alimentary system tumor incidence	J:66060
	decreased incidence of tumors by chemical induction	J:66060
	decreased mammary gland tumor incidence	J:66060
Apc^Min/Apc⁺ Tcf7^tm1Cle/Tcf7^tm1Cle involves: 129P2/OlaHsd * C57BL/6J	increased intestinal adenoma incidence	J:57721
	increased mammary adenoacanthoma incidence	J:57721
	increased salivary gland tumor incidence	J:57721
Apc^Min/Apc⁺ Dcc^tm1Wbg/Dcc⁺ involves: C57BL/6J	increased intestinal adenoma incidence	J:39765
Apc^Min/Apc⁺ Thbs1^tm1Hyn/Thbs1^tm1Hyn involves: C57BL/6J	abnormal intestine morphology	J:79641
	anemia	J:79641
	increased carcinoma incidence	J:79641
	increased intestinal adenoma incidence	J:79641
	increased tumor incidence	J:79641
	lordosis	J:79641
	premature death	J:79641
	weight loss	J:79641
Apc^Min/Apc⁺ Pten^tm1Hwu/Pten^tm1Hwu Tg(Vil1-cre)997Gum/0 involves: 129S4/SvJae * BALB/c * C57BL/6J * SJL	increased intestinal adenoma incidence	J:150553
	intestine polyps	J:150553
	premature death	J:150553
Apc^Min/Apc⁺ Ptgs2^tm1Unc/Ptgs2^tm1Unc involves: 129P2/OlaHsd * C57BL/6J	decreased prostaglandin level	J:64401
	decreased tumor incidence	J:64401
	intestine polyps	J:64401
	premature death	J:64401
Apc^Min/Apc⁺ Dnd1^Ter/Dnd1⁺ involves: 129P3/J * C57BL/6J	increased intestinal adenoma incidence	J:221231
Apc^Min/Apc⁺ Foxl1^tm1Khk/Foxl1^tm1Khk involves: 129P2/OlaHsd * C57BL/6	abnormal cell physiology	J:95893
	colon polyps	J:95893
	gastric polyps	J:95893
	increased colon adenoma incidence	J:95893
	normal neoplasm	J:95893
Apc^Min/Apc⁺ Egfr^Wa5/Egfr⁺ involves: BALB/cAnN * C3H/HeN * C57BL/6J	decreased tumor incidence	J:92308
Apc^Min/Apc⁺ Ccnd1^tm1Dsn/Ccnd1^tm1Dsn involves: C57BL/6J	increased intestinal adenoma incidence	J:78500
Apc^Min/Apc⁺ Cd44^tm1Mak/Cd44^tm1Mak involves: 129P2/OlaHsd * C57BL/6J	decreased intestinal adenoma incidence	J:135025
	increased small intestinal crypt cell apoptosis	J:135025
Apc^Min/Apc⁺ Cd44^tm1Mak/Cd44^tm1Mak involves: C57BL/6J	decreased intestinal adenoma incidence	J:204874
	increased enterocyte apoptosis	J:204874
	increased tumor-free survival time	J:204874
Apc^Min/Apc⁺ Hp^tm1Skl/Hp^tm1Skl involves: 129P2/OlaHsd * C57BL/6J	increased gastrointestinal tumor incidence	J:75249
Apc^Min/Apc⁺ Pla2g4a^tm1Jvb/Pla2g4a^tm1Jvb B6.Cg-Pla2g4a^tm1Jvb Apc^Min	intestine polyps	J:68495
Apc^Min/Apc⁺ Dnmt1^tm1Pwl/Dnmt1⁺ involves: 129S4/SvJae * C57BL/6J	intestine polyps	J:75230
Apc^Min/Apc⁺ Mbd4^tm1Bird/Mbd4^tm1Bird involves: 129P2/OlaHsd * C57BL/6J	abnormal DNA repair	J:77896
	increased intestinal adenoma incidence	J:77896
	premature death	J:77896
Apc^Min/Apc⁺ Esr1^tm1.1Mma/Esr1⁺ involves: 129S2/SvPas * C57BL/6J	abnormal colon goblet cell morphology	J:118600
	abnormal enterocyte proliferation	J:118600
	abnormal intestinal mucosa morphology	J:118600
	abnormal large intestine crypts of Lieberkuhn morphology	J:118600
	increased carcinoma incidence	J:118600
	increased colon adenoma incidence	J:118600
	increased gastrointestinal tumor incidence	J:118600
Apc^Min/Apc⁺ Esr1^tm1.1Mma/Esr1^tm1.1Mma involves: 129S2/SvPas * C57BL/6J	preweaning lethality, complete penetrance	J:118600
Apc^Min/Apc⁺ Esr2^tm1Mma/Esr2⁺ involves: 129S2/SvPas * C57BL/6J	abnormal enterocyte proliferation	J:118600
	increased gastrointestinal tumor incidence	J:118600
Apc^Min/Apc⁺ Esr2^tm1Mma/Esr2^tm1Mma involves: 129S2/SvPas * C57BL/6J	abnormal colon goblet cell morphology	J:118600
	abnormal enterocyte proliferation	J:118600
	colitis	J:118600
	increased colon adenoma incidence	J:118600
	increased gastrointestinal tumor incidence	J:118600
Apc^Min/Apc⁺ Brca2^tm1Mbn/Brca2⁺ B6.Cg-Brca2^tm1Mbn Apc^Min	abnormal adrenal gland morphology	J:67445
	abnormal mammary gland development	J:67445
	abnormal ovarian follicle morphology	J:67445
	abnormal ovarian folliculogenesis	J:67445
	abnormal vagina epithelium morphology	J:67445
	absent corpus luteum	J:67445
	absent mature ovarian follicles	J:67445
	absent nipple	J:67445
	normal growth/size/body region phenotype	J:67445
	increased incidence of induced tumors	J:67445
	increased incidence of tumors by chemical induction	J:67445
	increased mammary gland tumor incidence	J:67445
	ovary atrophy	J:67445
	normal reproductive system phenotype	J:67445
	uterus atrophy	J:67445
Apc^Min/Apc⁺ Mbd2^tm1Bh/Mbd2⁺ involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J	decreased tumor incidence	J:83087
	premature death	J:83087
Apc^Min/Apc⁺ Mbd2^tm1Bh/Mbd2^tm1Bh involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J	decreased tumor growth/size	J:83087
	decreased tumor incidence	J:83087
	normal mortality/aging	J:83087
Apc^Min/Apc⁺ Blm^tm1Grdn/Blm⁺ involves: 129P2/OlaHsd * 129S/SvEv * Black Swiss * C57BL/6J	increased colon adenoma incidence	J:79058
	increased gastrointestinal tumor incidence	J:79058
	increased intestinal adenoma incidence	J:79058
Apc^Min/Apc⁺ Myc^tm1Jlc/Myc⁺ involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J	abnormal digestive system physiology	J:134087
	abnormal hematopoietic system morphology/development	J:134087
	normal hematopoietic system phenotype	J:134087
	intestine polyps	J:134087
	normal mortality/aging	J:134087
Apc^Min/Apc⁺ Ptgds^tm1Ohy/Ptgds^tm1Ohy involves: 129P2/OlaHsd * C57BL/6J	increased intestinal adenoma incidence	J:118232
Apc^Min/Apc⁺ Trp53^tm2.1Tyj/Trp53^tm2.1Tyj Tg(Vil1-cre/ERT2)23Syr/0 involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2	decreased alimentary system tumor incidence	J:291671
	increased colon adenoma incidence	J:291671
	increased intestinal adenoma incidence	J:291671
Apc^Min/Apc⁺ Recql4^tm1Glu/Recql4^tm1Glu involves: 129S7/SvEvBrd * C57BL/6J	increased adenoma incidence	J:97101
	increased colon adenoma incidence	J:97101
	increased tumor growth/size	J:97101
Apc^Min/Apc⁺ Ereg^tm1Dwt/Ereg^tm1Dwt involves: 129S6/SvEvTac * C57BL/6J	increased intestinal adenoma incidence	J:93327
Apc^Min/Apc⁺ Erbb3^tm1.1Dwt/Erbb3^tm2.1Dwt Tg(Vil1-cre)997Gum/0 involves: 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL	decreased tumor incidence	J:152703
	normal digestive/alimentary phenotype	J:152703
	intestine polyps	J:152703
Apc^Min/Apc⁺ Atp5f1a^Mom2/Atp5f1a⁺ involves: C57BL/6J * DBA/2J	decreased tumor incidence	J:73854
Apc^Min/Apc⁺ Atp5f1a^Mom2/Atp5f1a^Mom2 involves: C57BL/6J * DBA/2J	decreased tumor incidence	J:73854
Apc^Min/Apc⁺ Zbtb33^tm1.1Bird/Y involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J	decreased tumor growth/size	J:104155
	increased intestinal adenoma incidence	J:104155
	premature death	J:104155
Apc^Min/Apc⁺ Dnmt3b^tm1Jae/Dnmt3b^tm1Jae Tg(Fabp1-cre)1Jig/0 involves: 129 * C57BL/6 * C57BL/6J * FVB/N	decreased tumor incidence	J:107386
Apc^Min/Apc⁺ Hpgds^tm1Urad/Hpgds⁺ involves: 129 * C57BL/6J	increased intestinal adenoma incidence	J:118232
Apc^Min/Apc⁺ Hpgds^tm1Urad/Hpgds^tm1Urad involves: 129 * C57BL/6J	increased intestinal adenoma incidence	J:118232
Apc^Min/Apc⁺ Tg(CAG-PGDS)S-55Hjl/0 involves: C57BL/6J * FVB/N	increased intestinal adenoma incidence	J:118232
Apc^Min/Apc⁺ Hdac2^{Gt(W035F03)Joe}/Hdac2^{Gt(W035F03)Joe} involves: 129S2/SvPas * C57BL/6J	decreased tumor incidence	J:152134
	increased small intestine adenocarcinoma incidence	J:152134
Apc^Min/Apc⁺ Il22^tm1Flv/Il22^tm1Flv involves: 129/Sv * C57BL/6 * C57BL/6J	decreased alimentary system tumor incidence	J:189217
Apc^Min/Apc⁺ Phgdh^tm1.1Shfu/Phgdh⁺ involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J	normal neoplasm	J:183477
Apc^Min/Apc⁺ Mmom1^C57BL/6J/Mmom1^FVB/NTac involves: C57BL/6J * FVB/NTac	decreased mammary gland tumor incidence	J:128481
Apc^Min/Apc⁺ Mmom1^C57BL/6J/Mmom1^FVB/NTac Mmom3^C57BL/6J/Mmom3^FVB/NTac involves: C57BL/6J * FVB/NTac	decreased mammary gland tumor incidence	J:128481
Apc^Min/Apc⁺ Mmom2^C57BL/6J/Mmom2^FVB/NTac involves: C57BL/6J * FVB/NTac	decreased mammary gland tumor incidence	J:128481
Apc^Min/Apc⁺ Mmom2^C57BL/6J/Mmom2^FVB/NTac Mmom3^C57BL/6J/Mmom3^FVB/NTac involves: C57BL/6J * FVB/NTac	decreased mammary gland tumor incidence	J:128481
Apc^Min/Apc⁺ Mmom2^C57BL/6J/Mmom2^FVB/NTac Mmom4^C57BL/6J/Mmom4^FVB/NTac involves: C57BL/6J * FVB/NTac	decreased mammary gland tumor incidence	J:128481
Apc^Min/Apc⁺ Mmom4^C57BL/6J/Mmom4^FVB/NTac involves: C57BL/6J * FVB/NTac	decreased mammary gland tumor incidence	J:128481
Apc^Min/Apc⁺ Mmom2^129X1/SvJ/Mmom2^C57BL/6J involves: 129X1/SvJ * C57BL/6J	decreased mammary gland tumor incidence	J:128481
Apc^Min/Apc⁺ Slc5a8^tm1.1Boet/Slc5a8^tm1.1Boet involves: C57BL/6 * C57BL/6J	increased colon adenoma incidence	J:139883
Apc^Min/Apc⁺ Glp2r^tm1Ddr/Glp2r⁺ involves: C57BL/6J	abnormal crypts of Lieberkuhn morphology	J:141821
	abnormal intestinal epithelium morphology	J:141821
	abnormal tumor morphology	J:141821
	increased intestinal adenoma incidence	J:141821
	intestine polyps	J:141821
Apc^Min/Apc⁺ Glp2r^tm1Ddr/Glp2r^tm1Ddr involves: C57BL/6J	abnormal crypts of Lieberkuhn morphology	J:141821
	abnormal intestinal epithelium morphology	J:141821
	abnormal tumor morphology	J:141821
	increased intestinal adenoma incidence	J:141821
	intestine polyps	J:141821
Apc^Min/Apc⁺ Tgfbr1^tm1Bopa/Tgfbr1⁺ B6.Cg-Tgfbr1^tm1Bopa Apc^Min	increased gastrointestinal tumor incidence	J:143706
	increased intestinal adenocarcinoma incidence	J:143706
Apc^Min/Apc⁺ Tgfbr1^tm1Bopa/Tgfbr1⁺ involves: 129S1/SvImJ * C57BL/6J	normal hematopoietic system phenotype	J:143706
	increased cell proliferation	J:143706
	increased gastrointestinal tumor incidence	J:143706
	increased intestinal adenocarcinoma incidence	J:143706
Apc^Min/Apc⁺ Ptprh^tm1.1Mato/Ptprh^tm1.1Mato involves: 129S4/SvJae * C57BL/6 * C57BL/6J	decreased incidence of induced tumors	J:146871
Apc^Min/Apc⁺ Mthfs^{Gt(RRK291)Byg}/Mthfs⁺ B6.Cg-Mthfs^{Gt(RRK291)Byg} Apc^Min	normal neoplasm	J:185874
Apc^Min/Apc⁺ Shmt1^{Gt(AD0236)Wtsi}/Shmt1^{Gt(AD0236)Wtsi} B6.Cg-Shmt1^{Gt(AD0236)Wtsi} Apc^Min	normal neoplasm	J:183477
Apc^Min/Apc⁺ Mom5^129P2/OlaHsd/? involves: 129P2/OlaHsd * C57BL/6J	decreased incidence of induced tumors	J:152194
Apc^Min/Apc⁺ Mom5^C57BL/6J/Mom5^C57BL/6J involves: C57BL/6J	increased intestinal adenoma incidence	J:152194
Apc^Min/Apc⁺ Col1a1^{tm1(CAG-Sirt1)Dsin}/Col1a1⁺ involves: 129S4/SvJae * C57BL/6 * C57BL/6J	anemia	J:134301
	cachexia	J:134301
	increased gastrointestinal tumor incidence	J:134301
Apc^Min/Apc⁺ Col1a1^{tm1(CAG-Sirt1)Dsin}/Col1a1⁺ Tg(Vil1-cre)997Gum/0 involves: 129S4/SvJae * C57BL/6 * C57BL/6J * SJL	decreased tumor incidence	J:134301
Apc^Min/Apc⁺ Rab25^tm1Jrgo/Rab25⁺ B6.Cg-Rab25^tm1Jrgo Apc^Min	increased intestinal adenoma incidence	J:158733
Apc^Min/Apc⁺ Rab25^tm1Jrgo/Rab25^tm1Jrgo B6.Cg-Rab25^tm1Jrgo Apc^Min	colon polyps	J:158733
	increased colon adenoma incidence	J:158733
	increased intestinal adenoma incidence	J:158733
Apc^Min/Apc⁺ Arhgef4^tm1Taki/Arhgef4⁺ B6J.Cg-Arhgef4^tm1Taki Apc^Min	decreased intestinal adenoma incidence	J:157023
	decreased tumor growth/size	J:157023
Apc^Min/Apc⁺ Arhgef4^tm1Taki/Arhgef4^tm1Taki B6J.Cg-Arhgef4^tm1Taki Apc^Min	decreased intestinal adenoma incidence	J:157023
	decreased tumor growth/size	J:157023
Apc^Min/Apc⁺ Arhgef4^tm1Taki/Arhgef4^tm1Taki Spata13^tm1Taki/Spata13^tm1Taki B6J.Cg-Arhgef4^tm1Taki Spata13^tm1Taki Apc^Min	abnormal tumor pathology	J:157023
	abnormal tumor vascularization	J:157023
	decreased intestinal adenoma incidence	J:157023
	decreased physiological sensitivity to xenobiotic	J:157023
	decreased tumor growth/size	J:157023
Apc^Min/Apc⁺ Gpa33^{tm1(GNAS)Wtsi}/Gpa33⁺ Hprt1^{tm1(CMV-cre)Brd}/? involves: 129S7/SvEvBrd * C57BL/6J	increased intestinal adenoma incidence	J:168378
Apc^Min/Apc⁺ Tcf7l2^{tm1.1(EGFP/cre)Mrc}/Tcf7l2⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	increased intestinal adenoma incidence	J:170088
Apc^Min/Apc⁺ Tcf7l2^tm2.2Mrc/Tcf7l2⁺ involves: C57BL/6J	increased intestinal adenoma incidence	J:170088
Apc^Min/Apc⁺ Tcf7l2^{tm1(EGFP/cre)Mrc}/Tcf7l2^tm2.1Mrc involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6J * C57BL/6NCrl	normal neoplasm	J:170088
Apc^Min/Apc⁺ Tg(Vil1-PPARGC1A)#Amos/0 involves: C57BL/6J * FVB/N	decreased alimentary system tumor incidence	J:171361
	decreased tumor growth/size	J:171361
Apc^Min/Apc⁺ Gt(ROSA)26Sor^{tm2(Rnf187)Jhai}/Gt(ROSA)26Sor⁺ Tg(Vil1-cre)20Syr/0 involves: 129S6/SvEvTac * C57BL/6 * DBA/2	increased gastrointestinal tumor incidence	J:173145
	increased tumor growth/size	J:173145
Apc^Min/Apc⁺ Col1a1^{tm9(tetO-Dnmt3b_i1)Jae}/Col1a1⁺ Gt(ROSA)26Sor^{tm1(rtTAM2)Jae}/Gt(ROSA)26Sor⁺ involves: 129S4/SvJae C57BL/6 * C57BL/6J	abnormal DNA methylation	J:127808
	increased intestinal adenoma incidence	J:127808
	increased tumor growth/size	J:127808
Apc^Min/Apc⁺ Col1a1^{tm10(tetO-Dnmt3b_i3)Jae}/Col1a1⁺ Gt(ROSA)26Sor^{tm1(rtTAM2)Jae}/Gt(ROSA)26Sor⁺ involves: 129S4/SvJae C57BL/6 * C57BL/6J	normal neoplasm	J:127808
Apc^Min/Apc⁺ Col1a1^{tm11(tetO-Dnmt3b_i6)Jae}/Col1a1⁺ Gt(ROSA)26Sor^{tm1(rtTAM2)Jae}/Gt(ROSA)26Sor⁺ involves: 129S4/SvJae C57BL/6 * C57BL/6J	normal neoplasm	J:127808
Apc^Min/Apc⁺ Col1a1^{tm12(tetO-Dnmt3a_i1)Jae}/Col1a1⁺ Gt(ROSA)26Sor^{tm1(rtTAM2)Jae}/Gt(ROSA)26Sor⁺ involves: 129S4/SvJae C57BL/6 * C57BL/6J	normal neoplasm	J:127808
Apc^Min/Apc⁺ Mir708^tm1Wtsi/Mir708^tm1Wtsi involves: C57BL/6J * C57BL/6N	abnormal intestinal epithelium physiology	J:317482
	increased colon adenoma incidence	J:317482
	premature death	J:317482
Apc^Min/Apc⁺ Il22ra2^tm2Vlcg/Il22ra2^tm2Vlcg involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NTac	increased intestinal adenoma incidence	J:189217
	increased tumor growth/size	J:189217
Apc^Min/Apc⁺ Dp(17Nfkbil1-Or2h1)1Cogr/0 involves: 129S6/SvEvTac * C57BL/6J	normal neoplasm	J:190754
Apc^Min/Apc⁺ Rr21^tm1Jta/Rr21⁺ involves: C57BL/6	intestine polyps	J:191217
Apc^Min/Apc⁺ Rr21^tm1.1Jta/Rr21^tm1.1Jta involves: C57BL/6 * FVB/N	intestine polyps	J:191217
Apc^Min/Apc⁺ Dclk1^{tm1.1(cre/ERT2)Seno}/Dclk1⁺ Gt(ROSA)26Sor^tm1Sor/Gt(ROSA)26Sor^{tm1(HBEGF)Awai} involves: 129S4/SvJaeSor * C57BL/6	abnormal tumor morphology	J:193873
	normal digestive/alimentary phenotype	J:193873
	normal endocrine/exocrine gland phenotype	J:193873
Apc^Min/Apc⁺ Dclk1^{tm1.1(cre/ERT2)Seno}/Dclk1^{tm1.1(cre/ERT2)Seno} involves: C57BL/6	intestine polyps	J:193873
Apc^Min/Apc⁺ Igf2bp1^tm1Vssp/Igf2bp1^tm1Vssp Tg(Vil1-cre)997Gum/0 involves: C57BL/6J * SJL	abnormal tumor incidence	J:202774
Apc^Min/Apc⁺ Cd44^tm1Stpa/Cd44^tm1Stpa involves: C57BL/6J * C57BL/6JIco	increased intestinal adenoma incidence	J:204874
	premature death	J:204874
Apc^Min/Apc⁺ Cd44^tm1Stpa/Cd44^tm2Stpa involves: C57BL/6J	increased intestinal adenoma incidence	J:204874
Apc^Min/Apc⁺ Cd44^tm2Stpa/Cd44^tm2Stpa involves: C57BL/6J	decreased intestinal adenoma incidence	J:204874
Apc^Min/Apc⁺ Cd44^tm2Stpa/Cd44^tm2Stpa involves: C57BL/6J	increased tumor-free survival time	J:204874
Apc^Min/Apc⁺ Hsd11b2^tm1.1Mzz/Hsd11b2^tm1.1Mzz Tg(Vil1-cre)997Gum/0 involves: 129 * C57BL/6 * C57BL/6J	abnormal corticosterone level	J:205456
	decreased tumor growth/size	J:205456
	increased intestinal adenoma incidence	J:205456
Apc^Min/Apc⁺ Mir10a^tm1.1Ahl/Mir10a^tm1.1Ahl B6.Cg-Mir10a^tm1.1Ahl Apc^min	increased gastrointestinal tumor incidence	J:205135
	increased intestinal adenoma incidence	J:205135
Apc^Min/Apc⁺ Rab11a^tm1.1Ngao/Rab11a^tm1.1Ngao Tg(Vil1-cre)997Gum/0 involves: 129S4/SvJae * C57BL/6J * SJL/J	decreased tumor-free survival time	J:278932
	increased intestinal adenoma incidence	J:278932
Apc^Min/Apc⁺ Ccdc80^tm1.1Ftk/Ccdc80^tm1.1Ftk involves: 129P2/OlaHsd * BALB/cJ * C57BL/6 * C57BL/6J * C57BL/6N	increased colon adenocarcinoma incidence	J:216704
	increased colon adenoma incidence	J:216704
	increased colon tumor incidence	J:216704
	increased gastrointestinal tumor incidence	J:216704
	intestine polyps	J:216704
	premature death	J:216704
Apc^Min/Apc⁺ Elp3^tm1.1Tac/Elp3^tm1.1Tac Tg(Vil1-cre)997Gum/0 involves: C57BL/6 * C57BL/6J * C57BL/6NTac * SJL	abnormal gastrointestinal brush cell morphology	J:227334
	abnormal intestinal epithelium morphology	J:227334
	decreased intestinal adenoma incidence	J:227334
	normal digestive/alimentary phenotype	J:227334
	normal hematopoietic system phenotype	J:227334
	normal immune system phenotype	J:227334
	increased tumor latency	J:227334
Apc^Min/Apc⁺ Lmna^tm4Stw/Lmna^tm4Stw Tg(Vil1-cre)997Gum/0 involves: C57BL/6 * C57BL/6J	duodenum polyps	J:220874
	jejunum polyps	J:220874
Apc^Min/Apc⁺ Spata13^tm1Taki/Spata13⁺ B6J.Cg-Spata13^tm1Taki Apc^Min	decreased intestinal adenoma incidence	J:157023
	decreased tumor growth/size	J:157023
Apc^Min/Apc⁺ Spata13^tm1Taki/Spata13^tm1Taki B6J.Cg-Spata13^tm1Taki Apc^Min	abnormal survival	J:157023
	decreased intestinal adenoma incidence	J:157023
	decreased tumor growth/size	J:157023
Apc^Min/Apc⁺ Hltf^tm1.1Hdin/Hltf^tm1.1Hdin involves: 129 * C57BL/6 * FVB/N	chromosomal instability	J:252991
	increased metastatic potential	J:252991
	normal neoplasm	J:252991
Apc^Min/Apc⁺ Tnik^tm1Teya/Tnik^tm1Teya involves: C57BL/6J	decreased alimentary system tumor incidence	J:241611
Apc^Min/Apc⁺ Spata18^tm1.2Hifa/Spata18⁺ involves: C57BL/6J	abnormal mitochondrial crista morphology	J:254117
	abnormal tumor susceptibility	J:254117
	anemia	J:254117
	increased classified tumor incidence	J:254117
	increased colon adenocarcinoma incidence	J:254117
	increased colon adenoma incidence	J:254117
	increased intestinal adenocarcinoma incidence	J:254117
	increased intestinal adenoma incidence	J:254117
	increased small intestine adenocarcinoma incidence	J:254117
	intestine polyps	J:254117
	premature death	J:254117
Apc^Min/Apc⁺ Spata18^tm1.2Hifa/Spata18^tm1.2Hifa involves: C57BL/6J	abnormal mitochondrial crista morphology	J:254117
	abnormal tumor susceptibility	J:254117
	anemia	J:254117
	increased classified tumor incidence	J:254117
	increased colon adenocarcinoma incidence	J:254117
	increased colon adenoma incidence	J:254117
	increased intestinal adenocarcinoma incidence	J:254117
	increased intestinal adenoma incidence	J:254117
	increased small intestine adenocarcinoma incidence	J:254117
	intestine polyps	J:254117
	premature death	J:254117
Apc^Min/Apc⁺ Tmem9^{tm1d(EUCOMM)Wtsi}/Tmem9⁺ involves: C57BL/6J * C57BL/6N	decreased intestinal adenoma incidence	J:268691
	extended life span	J:268691
Apc^Min/Apc⁺ Tmem9^{tm1d(EUCOMM)Wtsi}/Tmem9^{tm1d(EUCOMM)Wtsi} involves: C57BL/6J * C57BL/6N	abnormal tumor pathology	J:268691
	decreased intestinal adenoma incidence	J:268691
	decreased tumor growth/size	J:268691
	extended life span	J:268691
Apc^Min/Apc⁺ Col1a1^{tm11(tetO-Nup88)Jvd}/Col1a1⁺ involves: 129S4/SvJae * C57BL/6 * C57BL/6J	increased colon tumor incidence	J:231166
Apc^Min/Apc⁺ Mapkapk2^tm1.1Gkl/Mapkapk2^tm1.1Gkl Tg(Tie1-cre)9Ref/0 involves: 129S1/Sv * 129X1/SvJ * BALB/cJ * C57BL/6J	decreased tumor growth/size	J:262876
Apc^Min/Apc⁺ Mapkapk2^tm1.1Gkl/Mapkapk2^tm1.1Gkl Twist2^{tm1.1(cre)Dor}/Twist2⁺ involves: 129X1/SvJ * BALB/cJ * C57BL/6J	decreased tumor growth/size	J:262876
	decreased tumor incidence	J:262876
Apc^Min/Apc⁺ Mapkapk2^tm1.2Gkl/Mapkapk2^tm1.2Gkl involves: BALB/cJ * C57BL/6J	abnormal chemokine secretion	J:262876
	abnormal tumor vascularization	J:262876
	decreased interleukin-6 secretion	J:262876
	decreased tumor growth/size	J:262876
	decreased tumor incidence	J:262876
	normal hematopoietic system phenotype	J:262876
	increased intestinal adenoma incidence	J:262876
	increased tumor-free survival time	J:262876
	intestine polyps	J:262876
Apc^Min/Apc⁺ Bcl2l14^tm1.1Boui/Bcl2l14^tm1.1Boui involves: C57BL/6 * C57BL/6J	increased colon tumor incidence	J:296081
Apc^Min/Apc⁺ Map9^tm1.2Bcgen/Map9⁺ involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6 * C57BL/6J	increased colon tumor incidence	J:299895
Apc^Min/Apc⁺ Map9^tm1.2Bcgen/Map9^tm1.2Bcgen involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6 * C57BL/6J	increased colon tumor incidence	J:299895
	premature death	J:299895
Apc^Min/Apc⁺ Zfp82^tm1.2Cya/Zfp82⁺ involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6NTac	increased colon tumor incidence	J:316087
Apc^Min/Apc⁺ Zfp82^tm1.2Cya/Zfp82^tm1.2Cya involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6NTac	increased colon tumor incidence	J:316087
Apc^Min/Apc⁺ Fxyd5^em1Namje/Fxyd5^em1Namje C57BL/6J-Fxyd5^em1Namje Apc^min	increased gastrointestinal tumor incidence	J:325989
Apc^Min/Apc⁺ Del(15Rr357-Rr303293)2Jta/Del(15Rr357-Rr303293)2Jta involves: C57BL/6	decreased colon tumor incidence	J:257088
Apc^Min/Apc⁺ Tnfaip8l1^em1Huwa/Tnfaip8l1^em1Huwa involves: C57BL/6 * C57BL/6J	increased colon tumor incidence	J:342074
	premature death	J:342074
Apc^Min/Apc⁺ Zfp280c^em1Xss/Y C57BL/6J-Apc^Min Zfp280c^em1Xss	increased tumor-free survival time	J:331404
Apc^Min/Apc⁺ Zfp280c^em1Xss/Zfp280c⁺ C57BL/6J-Apc^Min Zfp280c^em1Xss	increased tumor-free survival time	J:331404
Apc^Min/Apc⁺ Zfp280c^em1Xss/Zfp280c^em1Xss C57BL/6J-Apc^Min Zfp280c^em1Xss	decreased alimentary system tumor incidence	J:331404
	increased tumor-free survival time	J:331404
Apc^Min/Apc^Min Asph^tm1Jed/Asph^tm1Jed involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6J * C57BL/6NTac	increased gastrointestinal tumor incidence	J:75888
	premature death	J:75888
Apc^Min/Apc^Min Ctnnb1^tm4.1Wbm/Ctnnb1⁺ involves: 129 * 129P2/OlaHsd * C57BL/6	embryonic lethality between implantation and somite formation, complete penetrance	J:156864
Apc^Min/Apc^Min Ppard^tm1.1Rev/Ppard^tm1.1Rev involves: C57BL/6J	colon polyps	J:73557
	increased intestinal adenoma incidence	J:73557
	intestine polyps	J:73557
Apc^Min/Apc^Min Rr27^tm1Rohl/Rr27⁺ involves: 129S1/Sv * 129X1/SvJ * C57BL/6J	abnormal crypts of Lieberkuhn morphology	J:97083
	increased colon adenoma incidence	J:97083
	increased intestinal adenoma incidence	J:97083
Apc^Min/Apc^Min Sat1^tm1Alh/Y involves: 129X1/SvJ * C57BL/6J	decreased tumor incidence	J:99381
Apc^Min/Apc^tm1Tno Ctnnb1^tm4.1Wbm/Ctnnb1⁺ involves: 129 * 129P2/OlaHsd * 129S4/SvJae * C57BL/6	normal craniofacial phenotype	J:156864
	increased hepatocellular carcinoma incidence	J:156864
	intestine polyps	J:156864
	normal nervous system phenotype	J:156864
Apc^tm1.1Tno/Apc⁺ Ctnna1^del/Ctnna1⁺ involves: 129S4/SvJae * C57BL/6	normal neoplasm	J:127452
Apc^tm1Cip/Apc⁺ H19^tm1Lda/H19⁺ involves: 129P2/OlaHsd * 129S2/SvPas	increased adenoma incidence	J:138826
Apc^tm1Cip/Apc⁺ H19^tm1Lda/H19⁺ involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * CBA	colon polyps	J:138826
	increased adenoma incidence	J:138826
	increased intestinal adenocarcinoma incidence	J:138826
Apc^tm1Cip/Apc⁺ Nrip1^tm1Mpk/Nrip1⁺ involves: 129P2/OlaHsd * C57BL/6J	premature death	J:211324
Apc^tm1Cip/Apc⁺ Cdhr5^tm1Lex/Cdhr5^tm1Lex involves: 129P2/OlaHsd * 129S5/SvEvBrd * C57BL/6	increased intestinal adenoma incidence	J:301471
	increased tumor growth/size	J:301471
Apc^tm1Cip/Apc⁺ Mki67^em1Dfis/Mki67^em1Dfis involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J	decreased incidence of tumors by chemical induction	J:304800
	decreased tumor growth/size	J:304800
Apc^tm1Hsa/Apc⁺ involves: 129P2/OlaHsd * C57BL/6	abnormal crypts of Lieberkuhn morphology	J:61978
	abnormal digestive system morphology	J:61978
	anemia	J:61978
	colon polyps	J:61978
	increased gastrointestinal tumor incidence	J:61978
	increased mammary adenocarcinoma incidence	J:61978
	increased mammary gland tumor incidence	J:61978
	increased stomach tumor incidence	J:61978
	intestinal hemorrhage	J:61978
	premature death	J:61978
Apc^tm1Hsa/Apc^tm1Hsa involves: 129P2/OlaHsd * C57BL/6	prenatal lethality, complete penetrance	J:61978
Apc^tm1Mmt/Apc⁺ Ptgs2^tm1Jed/Ptgs2⁺ involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J	abnormal intestine morphology	J:36816
	colon polyps	J:36816
Apc^tm1Mmt/Apc⁺ Ptgs2^tm1Jed/Ptgs2^tm1Jed involves: 129S2/SvPas * 129S7/SvEvBrd * C57BL/6J	abnormal intestine morphology	J:36816
Apc^tm1Mmt/Apc⁺ Smad4^tm1Mmt/Smad4⁺ involves: 129S2/SvPas * C57BL/6	epidermal cyst	J:46242
	increased intestinal adenocarcinoma incidence	J:46242
	increased pancreatic ductal adenocarcinoma incidence	J:46242
	premature death	J:46242
Apc^tm1Mmt/Apc⁺ Mmp7^tm1Lmm/Mmp7^tm1Lmm Smad4^tm1Mmt/Smad4⁺ involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ	decreased tumor growth/size	J:142797
	decreased tumor incidence	J:142797
Apc^tm1Mmt/Apc⁺ Smad2^tm1Kato/Smad2⁺ involves: 129S2/SvPas * 129S4/SvJae * C57BL/6J	decreased tumor-free survival time	J:79668
	increased intestinal adenoma incidence	J:79668
Apc^tm1Mmt/Apc⁺ Smad2^tm2Kato/Smad2⁺ involves: 129S2/SvPas * 129S4/SvJae * C57BL/6J	decreased tumor-free survival time	J:79668
	increased intestinal adenoma incidence	J:79668
Apc^tm1Mmt/Apc⁺ Nkd1^tm1Tko/Nkd1^tm1Tko involves: 129X1/SvJ	abnormal small intestine morphology	J:95901
Apc^tm1Rak/Apc⁺ Mlh1^tm1Rak/Mlh1⁺ involves: 129P2/OlaHsd * C57BL/6	increased gastrointestinal tumor incidence	J:53451
	increased tumor incidence	J:53451
	premature death	J:53451
Apc^tm1Rak/Apc⁺ Mlh1^tm1Rak/Mlh1^tm1Rak involves: 129P2/OlaHsd * C57BL/6	increased adenocarcinoma incidence	J:53451
	increased adenoma incidence	J:53451
	increased carcinoma incidence	J:53451
	increased gastrointestinal tumor incidence	J:53451
	increased lymphoma incidence	J:53451
	increased skin tumor incidence	J:53451
	increased tumor incidence	J:53451
	melena	J:53451
	premature death	J:53451
Apc^tm1Rak/Apc⁺ Msh2^tm1Rak/Msh2^tm1Rak involves: 129P2/OlaHsd	increased tumor incidence	J:64667
	premature death	J:64667
Apc^tm1Rak/Apc⁺ Cdh1^tm1Cbm/Cdh1⁺ involves: 129P2/OlaHsd * C57BL/6J	increased intestinal adenocarcinoma incidence	J:65142
	increased stomach tumor incidence	J:65142
Apc^tm1Rak/Apc⁺ Mbd4^tm1Wed/Mbd4^tm1Wed involves: 129/Sv * 129P2/OlaHsd * C57BL/6 * SJL	abnormal cell physiology	J:80319
	increased gastrointestinal tumor incidence	J:80319
Apc^tm1Rak/Apc⁺ Smad4^E6sad/Smad4⁺ B6.129P2-Apc^tm1Rak +/+ Smad4^E6sad	gastric polyps	J:107273
	increased intestinal adenocarcinoma incidence	J:107273
	increased intestinal adenoma incidence	J:107273
	premature death	J:107273
Apc^tm1Rak/Apc⁺ Smad4^E6sad/Smad4⁺ B6.129P2-Apc^tm1Rak Smad4^E6sad/+ +	anemia	J:107273
	enlarged spleen	J:107273
	gastric polyps	J:107273
	increased intestinal adenoma incidence	J:107273
	intestine polyps	J:107273
	premature death	J:107273
Apc^tm1Rak/Apc⁺ Hmmr^tm1Baa/Hmmr^tm1Baa involves: 129P2/OlaHsd * C57BL/6	decreased tumor incidence	J:86065
Apc^tm1Rak/Apc⁺ Dcc^tm1.1Mehl/Dcc^tm1.1Mehl involves: 129P2/OlaHsd * C57BL/6	increased gastrointestinal tumor incidence	J:181517
	increased intestinal adenocarcinoma incidence	J:181517
	increased metastatic potential	J:181517
Apc^tm1Rak/Apc⁺ Ctnnb1^tm1.2Wvv/Ctnnb1⁺ involves: 129P2/OlaHsd * C57BL/6J	abnormal telencephalon development	J:185942
	embryonic lethality, complete penetrance	J:185942
	rostral body truncation	J:185942
Apc^tm1Rak/Apc⁺ Pms2^tm1.1Sks/Pms2^tm1.1Sks involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J	intestine polyps	J:310354
Apc^tm1Rsmi/Apc⁺ Ctnnb1^tm1Wvv/Ctnnb1⁺ Tg(Fabp1-cre)1Jig/? involves: 129P2/OlaHsd * C57BL/6J * FVB/N	increased gastrointestinal tumor incidence	J:185942
Apc^tm1Tno/Apc⁺ Pten^tm2Mak/Pten^tm2Mak Tg(Cyp1a1-cre/ERT)1Dwi/0 involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * CBA	abnormal small intestine morphology	J:143082
	increased intestinal adenocarcinoma incidence	J:143082
	peritoneal inflammation	J:143082
	premature death	J:143082
Apc^tm1Tno/Apc⁺ Il17ra^tm1Koll/Il17ra^tm1Koll Tg(CDX2-cre)101Erf/0 involves: 129 * 129S4/SvJae * C57BL/6J * SJL/J	decreased tumor growth/size	J:189226
Apc^tm1Tno/Apc⁺ Il23a^tm1Ngh/Il23a^tm1Ngh Tg(CDX2-cre)101Erf/0 involves: 129 * 129S4/SvJae * C57BL/6J * SJL/J	decreased tumor growth/size	J:189226
Apc^tm1Tno/Apc⁺ Il23r^tm1.2Trin/Il23r^tm1.2Trin Tg(CDX2-cre)101Erf/0 involves: 129S4/SvJae * C57BL/6 * C57BL/6J * SJL/J	decreased tumor growth/size	J:189226
Apc^tm1Tno/Apc⁺ Brf1^tm1Arte/Brf1^tm1Arte Tg(Cyp1a1-cre)1Dwi/0 involves: C57BL/6 * CBA	increased pancreatic ductal adenocarcinoma incidence	J:285667
Apc^tm1Tno/Apc⁺ Rac3^tm1.1Bea/Rac3^tm1.1Bea Tg(Vil1-cre/ERT2)23Syr/0 involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2	abnormal tumor susceptibility	J:306088
	decreased alimentary system tumor incidence	J:306088
	decreased intestinal adenoma incidence	J:306088
	decreased tumor growth/size	J:306088
Apc^tm1Tno/Apc^tm1Tno Ctnnb1^tm4.1Wbm/Ctnnb1⁺ involves: 129 * 129P2/OlaHsd * 129S4/SvJae * C57BL/6	decreased tumor incidence	J:156864
Apc^tm1Tno/Apc^tm1Tno Elp3^tm1.1Tac/Elp3^tm1.1Tac Lgr5^{tm1(cre/ERT2)Cle}/Lgr5⁺ involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * C57BL/6NTac	abnormal intestinal epithelium morphology	J:227334
	abnormal small intestinal crypt cell physiology	J:227334
	decreased tumor growth/size	J:227334
Apc^tm1Tno/Apc^tm1Tno Gsk3a^tm1Jrw/Gsk3a^tm1Jrw Gsk3b^tm2Jrw/Gsk3b^tm2Jrw involves: 129 * C57BL/6 * CBA	abnormal urinary bladder urothelium morphology	J:164579
Apc^tm1Tno/Apc^tm1Tno Pten^tm1Hwu/Pten^tm1Hwu Tg(Cyp1a1-cre/ERT)1Dwi/0 involves: 129S4/SvJae * C57BL/6 * CBA	abnormal urinary bladder urothelium morphology	J:164579
Apc^tm1Tno/Apc^tm1Tno Pten^tm2Mak/Pten^tm2Mak involves: 129P2/OlaHsd * 129S4/SvJae	decreased tumor-free survival time	J:120955
	hemorrhagic ascites	J:120955
	increased ovarian carcinoma incidence	J:120955
Apc^tm2.1Cip/Apc⁺ Kras^tm4Tyj/Kras⁺ Tg(Fabp1-cre)1Jig/0 involves: 129P2/OlaHsd * 129S4/SvJae * FVB	increased intestinal adenocarcinoma incidence	J:132357
	premature death	J:132357
Apc^tm2.1Cip/Apc⁺ Atg7^tm1Tchi/Atg7^tm1Tchi Tg(Vil1-cre/ERT2)23Syr/0 involves: 129P2/OlaHsd * C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj * DBA/2	abnormal gut flora balance	J:227287
	abnormal immune system physiology	J:227287
	abnormal intestinal goblet cell morphology	J:227287
	abnormal intestine physiology	J:227287
	abnormal Paneth cell morphology	J:227287
	decreased intestinal adenoma incidence	J:227287
	increased CD8-positive, alpha-beta T cell number	J:227287
	increased CD103-positive CD11b-low dendritic cell number	J:227287
	increased interleukin-1 beta secretion	J:227287
	increased interleukin-10 secretion	J:227287
	increased regulatory T cell number	J:227287
Apc^tm2.1Cip/Apc^tm2.1Cip Lect2^tm1Ymg/Lect2^tm1Ymg Tg(Ttr-cre/Esr1)1Vco/0 B6.Cg-Lect2^tm1Ymg Apc^tm2.1Cip Tg(Ttr-cre/Esr1)1Vco	abnormal chemokine level	J:184496
	abnormal circulating enzyme level	J:184496
	abnormal liver morphology	J:184496
	abnormal neutrophil physiology	J:184496
	abnormal NK T cell physiology	J:184496
	decreased interferon-gamma secretion	J:184496
	hepatic necrosis	J:184496
	increased hepatocyte apoptosis	J:184496
	increased interleukin-4 secretion	J:184496
	increased NK T cell number	J:184496
	liver inflammation	J:184496
	premature death	J:184496
Apc^tm2Rak/Apc⁺ Trp53^tm1Brn/Trp53^tm1Brn Tg(Pdx1-cre)6Tuv/0 involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL	abnormal cytokine level	J:234310
	increased circulating cholesterol level	J:234310
	increased circulating triglyceride level	J:234310
	increased cystadenoma incidence	J:234310
	increased metastatic potential	J:234310
	increased pancreas tumor incidence	J:234310
	premature death	J:234310
Apc^tm2Rak/Apc⁺ Kras^tm4Tyj/Kras⁺ Tg(Fabp1-cre)1Jig/0 involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL	increased colon adenoma incidence	J:276349
	premature death	J:276349
Apc^tm2Rak/Apc⁺ Kras^tm1.1Khai/Kras⁺ Tg(Fabp1-cre)1Jig/0 involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * FVB/N * SJL	increased colon adenoma incidence	J:276349
	premature death	J:276349
Apc^tm2Rak/Apc^tm2Rak Kras^tm4Tyj/Kras⁺ involves: 129 * 129S4/SvJae * C57BL/6J * SJL	increased adenocarcinoma incidence	J:156532
	increased carcinoma incidence	J:156532
	increased colon adenoma incidence	J:156532
	increased organ/body region tumor incidence	J:156532
Apc^tm2Rfo/Apc⁺ Smad4^E6sad/Smad4⁺ involves: 129P2/OlaHsd * C57BL/6J	increased gastrointestinal tumor incidence	J:151494
	increased mammary adenocarcinoma incidence	J:151494
Apc^tm2Rfo/Apc⁺ Ctnnb1^tm1.2Wvv/Ctnnb1⁺ involves: 129P2/OlaHsd * C57BL/6J	embryonic lethality, complete penetrance	J:185942
	rostral body truncation	J:185942
Bmi1^tm1.1Lees/Bmi1^tm1.1Lees Apc^tm2Cip/Apc⁺ Tg(Vil1-cre)20Syr/0 involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2	normal cellular phenotype	J:204354
	decreased alimentary system tumor incidence	J:204354
	decreased colon tumor incidence	J:204354
	decreased intestinal adenoma incidence	J:204354
Bmi1^tm1Brn/Bmi1^tm1Brn Apc^tm2Cip/Apc⁺ Cdkn2a^tm1Cjs/Cdkn2a^tm1Cjs Tg(Vil1-cre)20Syr/0 involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * DBA/2	cachexia	J:204354
	hunched posture	J:204354
	increased intestinal adenoma incidence	J:204354
Bmi1^tm1Brn/Bmi1^tm1Brn Apc^tm2Cip/Apc⁺ Tg(Vil1-cre)20Syr/0 involves: 129P2/OlaHsd * C57BL/6 * DBA/2	decreased alimentary system tumor incidence	J:204354
	decreased colon tumor incidence	J:204354
	decreased intestinal adenoma incidence	J:204354
	increased apoptosis	J:204354
Cdx2^tm1Mmt/Cdx2⁺ Apc^tm1Mmt/Apc⁺ B6.129-Cdx2^tm1Mmt Apc^tm1Mmt	abnormal cell cycle checkpoint function	J:86737
	abnormal chromosome morphology	J:86737
	abnormal colon morphology	J:86737
	abnormal small intestine morphology	J:86737
	colon polyps	J:86737
	decreased apoptosis	J:86737
	increased apoptosis	J:86737
Fen1^tm1Rak/Fen1⁺ Apc^tm1Rak/Apc⁺ involves: 129/Sv * 129P2/OlaHsd * C57BL/6 * SJL/J	abnormal cell physiology	J:77962
	increased gastrointestinal tumor incidence	J:77962
	increased malignant tumor incidence	J:77962
	premature death	J:77962
Gata6os^em1Zfa/Gata6os^em1Zfa Apc^Min/Apc⁺ involves: C57BL/6J	decreased intestinal adenoma incidence	J:268724
	extended life span	J:268724
Tigar^{Gt(EUCE0047g05)Hmgu}/Tigar^{Gt(EUCE0047g05)Hmgu} Apc^tm1Tno/Apc^tm1Tno Lgr5^{tm1(cre/ERT2)Cle}/Lgr5⁺ involves: 129P2/OlaHsd * 129S4/SvJae	decreased susceptibility to induced morbidity/mortality	J:198650
	decreased tumor growth/size	J:198650
Tle5^tm1.1Mmt/Tle5^tm1.1Mmt Apc^tm1Mmt/Apc⁺ Tg(Vil1-cre/ERT2)23Syr/0 involves: 129S2/SvPas * C57BL/6 * DBA * SJL	increased colon adenocarcinoma incidence	J:168065
	increased metastatic potential	J:168065
	increased small intestine adenocarcinoma incidence	J:168065

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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