Apex1 Phenotype Annotations - Multigenic Genotypes

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Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Apex1
apurinic/apyrimidinic endonuclease 1
MGI:88042

4 phenotypes from multigenic genotypes

Allelic Composition Genetic Background	Annotated Term	Reference
Apex1^tm1Djc/Apex1⁺ Tg(TacLIZa)A1Jsh/0 involves: 129X1/SvJ * C57BL/6 * NTac:NIHBS	abnormal cell physiology	J:92957
	abnormal DNA repair	J:92957
Apex1^tm1Ecf/Apex1⁺ Xpc^tm1Ecf/Xpc^tm1Ecf involves: 129	increased tumor incidence	J:70397
Apex1^tm1Ecf/Apex1⁺ Xpc^tm1Ecf/Xpc^tm1Ecf involves: 129	oxidative stress	J:70397

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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