Apoa1 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Apoa1
apolipoprotein A-I
MGI:88049

10 phenotypes from 2 alleles in 5 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Apoa1^tm1Bres/Apoa1⁺ involves: 129S4/SvJae * C57BL/6	decreased cholesterol efflux	J:40819
Apoa1^tm1Bres/Apoa1⁺ involves: 129S4/SvJae * C57BL/6	decreased circulating HDL cholesterol level	J:40819
Apoa1^tm1Bres/Apoa1^tm1Bres involves: 129S4/SvJae * C57BL/6	decreased cholesterol efflux	J:40819
	decreased circulating cholesterol level	J:40819
	decreased circulating HDL cholesterol level	J:40819
	decreased circulating LDL cholesterol level	J:40819
	decreased circulating VLDL cholesterol level	J:40819
	increased circulating triglyceride level	J:40819
Apoa1^tm1Unc/Apoa1⁺ B6.129P2-Apoa1^tm1Unc	decreased circulating cholesterol level	J:22986
Apoa1^tm1Unc/Apoa1⁺ involves: 129P2/OlaHsd * C57BL/6J	decreased circulating cholesterol level	J:2109
Apoa1^tm1Unc/Apoa1⁺ involves: 129P2/OlaHsd * C57BL/6J	decreased circulating HDL cholesterol level	J:2109
Apoa1^tm1Unc/Apoa1^tm1Unc B6.129P2-Apoa1^tm1Unc	decreased circulating cholesterol level	J:22986
Apoa1^tm1Unc/Apoa1^tm1Unc B6.129P2-Apoa1^tm1Unc/J	abnormal vascular wound healing	J:118063
	decreased circulating cholesterol level	J:114205
	decreased circulating HDL cholesterol level	J:114205
	decreased circulating phospholipid level	J:114205
	increased circulating cholesterol level	J:114205
	increased circulating triglyceride level	J:114205
Apoa1^tm1Unc/Apoa1^tm1Unc involves: 129P2/OlaHsd	abnormal cellular cholesterol metabolism	J:120501
	decreased cholesterol efflux	J:129136
	decreased circulating cholesterol level	J:129136
	decreased circulating HDL cholesterol level	J:129136
	decreased circulating phospholipid level	J:129136
Apoa1^tm1Unc/Apoa1^tm1Unc involves: 129P2/OlaHsd * C57BL/6J	decreased circulating cholesterol level	J:2109
Apoa1^tm1Unc/Apoa1^tm1Unc involves: 129P2/OlaHsd * C57BL/6J	decreased circulating HDL cholesterol level	J:2109

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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