Apoc3 Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Apoc3
apolipoprotein C-III
MGI:88055

16 phenotypes from 1 allele in 3 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Apoc3^tm1Unc/Apoc3⁺ involves: 129	decreased circulating cholesterol level	J:21750
	decreased circulating LDL cholesterol level	J:21750
	decreased circulating triglyceride level	J:21750
	decreased circulating VLDL cholesterol level	J:21750
Apoc3^tm1Unc/Apoc3⁺ involves: 129P2/OlaHsd * C57BL/6J	decreased circulating cholesterol level	J:21750
	decreased circulating HDL cholesterol level	J:21750
	decreased circulating triglyceride level	J:21750
Apoc3^tm1Unc/Apoc3^tm1Unc B6.129-Apoc3^tm1Unc/J	abnormal blood homeostasis	J:105136
	decreased circulating triglyceride level	J:105136
	decreased energy expenditure	J:105136
	increased circulating glucose level	J:105136
	increased circulating ketone body level	J:105136
	increased circulating leptin level	J:105136
	increased food intake	J:105136
	increased susceptibility to diet-induced obesity	J:105136
	increased white adipose tissue amount	J:105136
	insulin resistance	J:105136
	lipidosis	J:105136
Apoc3^tm1Unc/Apoc3^tm1Unc involves: 129	decreased circulating cholesterol level	J:21750
	decreased circulating LDL cholesterol level	J:21750
	decreased circulating triglyceride level	J:21750
	decreased circulating VLDL cholesterol level	J:21750
Apoc3^tm1Unc/Apoc3^tm1Unc involves: 129P2/OlaHsd * C57BL/6J	abnormal lipid homeostasis	J:21750
	decreased circulating cholesterol level	J:21750
	decreased circulating HDL cholesterol level	J:21750
	decreased circulating LDL cholesterol level	J:21750
	decreased circulating triglyceride level	J:21750
	decreased circulating VLDL cholesterol level	J:21750

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24