Aprt Phenotype Annotations

Mammalian Phenotype Ontology Annotations
Query Results - Summary

Symbol
Name
ID

Aprt
adenine phosphoribosyl transferase
MGI:88061

47 phenotypes from 4 alleles in 6 genetic backgrounds

Allelic Composition Genetic Background	Annotated Term	Reference
Aprt^{em1(IMPC)Hmgu}/Aprt⁺ C57BL/6NCrl-Aprt^{em1(IMPC)Hmgu}/Ieg	increased respiratory quotient	J:211773
Aprt^{em1(IMPC)Hmgu}/Aprt^{em1(IMPC)Hmgu} C57BL/6NCrl-Aprt^{em1(IMPC)Hmgu}/Ieg	abnormal retina morphology	J:211773
	preweaning lethality, incomplete penetrance	J:211773
Aprt^tm1Dwm/Aprt^tm1Dwm 129P2/OlaHsd-Aprt^tm1Dwm	abnormal coat appearance	J:38450
	abnormal kidney morphology	J:38450
	abnormal proximal convoluted tubule morphology	J:38450
	abnormal urinary bladder morphology	J:38450
	aminoaciduria	J:38450
	colorless urine	J:38450
	decreased body size	J:38450
	dilated renal glomerular capsule	J:38450
	dilated renal tubule	J:38450
	hunched posture	J:38450
	hydronephrosis	J:38450
	kidney cortex atrophy	J:38450
	kidney medulla atrophy	J:38450
	nephrolithiasis	J:38450
	premature death	J:38450
	preweaning lethality, incomplete penetrance	J:38450
	pyelonephritis	J:38450
	reduced fertility	J:38450
	renal cast	J:38450
	renal interstitial fibrosis	J:38450
	small kidney	J:38450
Aprt^tm1Dwm/Aprt^tm1Dwm involves: 129P2/OlaHsd * BALB/c	abnormal coat appearance	J:38450
	abnormal kidney medulla morphology	J:38450
	abnormal kidney morphology	J:38450
	abnormal proximal convoluted tubule morphology	J:38450
	abnormal urinary bladder morphology	J:38450
	abnormal urine homeostasis	J:38450
	abnormal urine nucleoside level	J:38450
	decreased body size	J:38450
	dilated renal glomerular capsule	J:38450
	dilated renal tubule	J:38450
	hunched posture	J:38450
	hydronephrosis	J:38450
	postnatal lethality, incomplete penetrance	J:38450
	premature death	J:38450
	reduced fertility	J:38450
	renal cast	J:38450
	small kidney	J:38450
Aprt^tm1Jat/Aprt⁺ involves: 129S2/SvPas * C57BL/6J	nephrolithiasis	J:103956
Aprt^tm1Jat/Aprt^tm1Jat involves: 129S2/SvPas * Black Swiss	abnormal urine nucleoside level	J:33255
	crystalluria	J:111451
	cystolithiasis	J:33255
	decreased creatinine clearance	J:111451
	decreased hematocrit	J:111451
	decreased kidney weight	J:111451
	decreased urine uric acid level	J:33255
	dilated renal tubule	J:33255
	disheveled coat	J:33255
	hunched posture	J:33255
	increased blood urea nitrogen level	J:111451
	increased fluid intake	J:111451
	kidney atrophy	J:111451
	kidney inflammation	J:33255
	nephrolithiasis	J:33255, J:111451
	polyuria	J:111451
	premature death	J:33255
	renal fibrosis	J:33255
	renal tubular necrosis	J:33255, J:111451
	normal reproductive system phenotype	J:33255
	weight loss	J:33255, J:111451
Aprt^tm1Jat/Aprt^tm1Jat involves: 129S2/SvPas * C57BL/6J	abnormal urine nucleoside level	J:33255
	cystolithiasis	J:33255, J:103956
	decreased urine uric acid level	J:33255
	disheveled coat	J:33255
	hunched posture	J:33255
	kidney collecting duct atrophy	J:103956
	kidney inflammation	J:33255
	nephrolithiasis	J:103956
	premature death	J:33255
	reduced fertility	J:33255
	renal interstitial fibrosis	J:33255, J:103956
	renal tubule atrophy	J:103956
	weight loss	J:33255
Aprt^tm1Vri/Aprt^tm1Vri involves: 129P2/OlaHsd * C57BL/6	abnormal kidney morphology	J:50874
	decreased body size	J:50874
	dehydration	J:50874
	hunched posture	J:50874
	kidney failure	J:50874
	kidney inflammation	J:50874
	nephrolithiasis	J:50874
	postnatal lethality, incomplete penetrance	J:50874
	premature death	J:50874
	reduced fertility	J:50874
	renal fibrosis	J:50874

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