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Mammalian Phenotype Ontology Annotations
Query Results - Summary
Symbol
Name
ID 		Ar
androgen receptor
MGI:88064
168 phenotypes from 16 alleles in 35 genetic backgrounds
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Allelic Composition
Genetic Background		 Annotated Term Reference
Amhr2tm3(cre)Bhr/Amhr2+
Artm1Chc/Y
involves: 129S/SvEv * C57BL/6 		abnormal meiosis J:118270
abnormal seminiferous tubule morphology J:118270
arrest of male meiosis J:118270
arrest of spermatogenesis J:118270
azoospermia J:118270
decreased circulating testosterone level J:118270
male infertility J:118270
small seminiferous tubules J:118270
small testis J:118270
Arem1Liuy/Y
involves: C57BL/6J * CBA 		secondary sex reversal J:202050
small testis J:202050
ArTfm-Jms/Y
involves: C57BL/6JJms 		abnormal secondary sex determination J:19298
secondary sex reversal J:19298
small testis J:19298
ArTfm-Jms/ArTfm-Jms
involves: C57BL/6JJms 		female infertility J:19298
increased body weight J:19298
ArTfm/Y
involves: NMRI * STOCK EdaTa Atp7aMo-blo 		abnormal seminiferous tubule morphology J:140803
arrest of male meiosis J:140803
cryptorchism J:140803
enlarged seminiferous tubules J:140803
increased Leydig cell number J:140803
increased testis tumor incidence J:140803
secondary sex reversal J:140803
ArTfm/Y
involves: STOCK EdaTa Atp7aMo-blo 		abnormal bone marrow cell number J:110923
abnormal erythropoiesis J:110923
abnormal myeloid leukocyte morphology J:110923
abnormal seminiferous tubule morphology J:140803
arrest of male meiosis J:140803
increased immature B cell number J:110923
secondary sex reversal J:140803
ArTfm/Y
Not Specified 		abnormal adult Leydig cell differentiation J:65900
abnormal mammary gland sensory innervation pattern J:192549
abnormal spermatogenesis J:65900
abnormal testis morphology J:65900
ArTfm/Y
STOCK EdaTa Atp7aMo-blo/+ + 		abnormal anogenital distance J:5173
abnormal female reproductive system morphology J:5173
abnormal gametogenesis J:5173
abnormal male reproductive system morphology J:5173
abnormal secondary sex determination J:5173
abnormal social/conspecific interaction behavior J:5173
absent epididymis J:5173
absent vas deferens J:5173
arrest of male meiosis J:5173
cryptorchism J:5173
Leydig cell hypertrophy J:5173
male pseudohermaphroditism J:5173
secondary sex reversal J:5173
small testis J:5173
vagina atresia J:5173
Artm1.1Chc/Y
involves: 129S/SvEv * C57BL/6 * FVB/N 		abnormal tumor morphology J:120844
absent epididymis J:89886
absent prostate gland J:89886
absent seminal vesicle J:89886
arrest of spermatogenesis J:89886
decreased circulating testosterone level J:89886
decreased incidence of tumors by chemical induction J:120844
increased circulating luteinizing hormone level J:89886
preneoplasia J:120844
small testis J:89886
Artm1.1Chc/Artm1.1Chc
involves: 129S/SvEv * C57BL/6 * FVB/N 		decreased incidence of tumors by chemical induction J:120844
preneoplasia J:120844
Artm1.1Jdz/Y
B6.129X1-Artm1.1Jdz 		abnormal male reproductive system morphology J:123057
abnormal testis morphology J:123057
absent prostate gland J:123057
absent seminal vesicle J:123057
arrest of male meiosis J:123057
arrest of spermatogenesis J:123057
azoospermia J:123057
cryptorchism J:123057
decreased body weight J:123057
decreased circulating testosterone level J:123057
decreased male germ cell number J:123057
decreased testis weight J:123057
secondary sex reversal J:123057
small seminiferous tubules J:123057
small testis J:123057
Artm1.1Jdz/Y
involves: 129X1/SvJ * C57BL/6 		abnormal testis morphology J:122327
absent epididymis J:122327
absent prostate gland J:122327
absent scrotum J:122327
absent seminal vesicle J:122327
cryptorchism J:122327
decreased circulating testosterone level J:122327
decreased testis weight J:122327
normal growth/size/body region phenotype J:122327
short perineum J:122327
Artm1.1Reb/Y
involves: 129S4/SvJaeSor * C57BL/6 * DBA/2J 		arrest of male meiosis J:90393
cryptorchism J:90393
male pseudohermaphroditism J:90393
secondary sex reversal J:90393
small testis J:90393
Artm1.1Verh/Y
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 		abnormal male reproductive system morphology J:88169
abnormal peritubular myoid cell morphology J:88169
abnormal postnatal growth J:88169
abnormal secondary sex determination J:88169
abnormal spermatogenesis J:88169
absent epididymis J:88169
absent seminal vesicle J:88169, J:100799
absent vas deferens J:88169
absent Wolffian ducts J:88169
azoospermia J:88169
cryptorchism J:88169
decreased Leydig cell number J:100799
decreased male germ cell number J:88169
decreased testis weight J:88169, J:100799
increased circulating luteinizing hormone level J:100799
increased male germ cell apoptosis J:88169
secondary sex reversal J:88169
small seminiferous tubules J:88169
small testis J:88169
Artm1Chc/Y
involves: 129S/SvEv * C57BL/6J 		no abnormal phenotype detected J:81789
Artm1Chc/Ar+
Tmem163Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N 		decreased litter size J:81789
Artm1Chc/Artm1.1Chc
Tmem163Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N 		abnormal branching of the mammary ductal tree J:87193
abnormal lactation J:87193
abnormal mammary gland morphology J:87193
abnormal nursing J:87193
decreased litter size J:81789
decreased ovary weight J:87193
decreased oviduct weight J:87193
decreased uterus weight J:87193
enlarged thymus J:87193
Artm1Chc/Y
Plekha5Tg(AMH-cre)1Flor/Plekha5+
involves: 129S/SvEv * C57BL/6 * SJL 		abnormal meiosis J:118270
abnormal seminiferous tubule morphology J:89886, J:118270
abnormal spermatogenesis J:89886
arrest of male meiosis J:89886, J:118270
azoospermia J:89886, J:118270
decreased circulating testosterone level J:89886, J:118270
decreased male germ cell number J:89886
decreased testis weight J:89886
increased circulating follicle stimulating hormone level J:89886
increased circulating luteinizing hormone level J:89886
male infertility J:89886, J:118270
small testis J:118270
Artm1Chc/Y
Tg(Pbsn-cre)4Prb/0
involves: 129S/SvEv * C57BL/6 * DBA/2 		abnormal prostate gland epithelium morphology J:123402
abnormal prostate gland morphology J:123402
enlarged prostate gland ventral lobe J:123402
normal homeostasis/metabolism phenotype J:123402
normal reproductive system phenotype J:123402
Artm1Chc/Y
Tg(Sycp1-cre)4Min/0
involves: 129S/SvEv * C57BL/6 * DBA/2 		normal reproductive system phenotype J:118270
Artm1Chc/Y
Tmem163Tg(ACTB-cre)2Mrt/0
involves: 129S/SvEv * C57BL/6J * FVB/N 		abnormal anogenital distance J:81789
abnormal external male genitalia morphology J:81789
abnormal fat cell morphology J:81789, J:98775
abnormal long bone metaphysis morphology J:81789
abnormal scrotum morphology J:81789
abnormal seminiferous tubule morphology J:118270
abnormal Sertoli cell morphology J:81789, J:118270
abnormal spermatocyte morphology J:118270
abnormal spermatogonia morphology J:81789
abnormal trabecular bone morphology J:81789
absent epididymis J:81789
absent external male genitalia J:81789
absent prostate gland J:81789
absent seminal vesicle J:81789
absent vas deferens J:81789
arrest of male meiosis J:118270
arrest of spermatogenesis J:81789
cryptorchism J:81789, J:118270
decreased adiponectin level J:98775
decreased body weight J:81789, J:98775
decreased circulating testosterone level J:81789, J:98775, J:118270
decreased response to leptin J:81789
hyperglycemia J:98775
hypospadia J:81789
impaired glucose tolerance J:98775
increased bone ossification J:81789
increased circulating glucose level J:98775
increased circulating insulin level J:98775
increased circulating leptin level J:98775
increased circulating triglyceride level J:98775
increased gonadal fat pad weight J:98775
increased liver triglyceride level J:98775
increased osteoclast cell number J:81789
increased renal fat pad weight J:98775
increased skeletal muscle triglyceride level J:98775
increased susceptibility to weight gain J:98775
increased white adipose tissue amount J:98775
insulin resistance J:98775
Leydig cell hypertrophy J:81789
seminiferous tubule degeneration J:118270
small penis J:81789
small seminiferous tubules J:118270
small testis J:118270
testicular atrophy J:98775
testis hypoplasia J:81789
Artm1Fcl/Y
involves: 129S2/SvPas * C57BL/6 		decreased epididymis weight J:120102
decreased germ cell number J:120102
decreased litter size J:120102
decreased prostate gland anterior lobe weight J:120102
decreased prostate gland ventral lobe weight J:120102
decreased seminal vesicle weight J:120102
decreased Sertoli cell number J:120102
decreased testis weight J:120102
reduced male fertility J:120102
small seminiferous tubules J:120102
Artm1Fcl/Artm1Fcl
involves: 129S2/SvPas * C57BL/6 		no abnormal phenotype detected J:120102
Artm1Jdz/Y
B6.129X1-Artm1Jdz 		no abnormal phenotype detected J:123057
Artm1Jdz/Y
Plekha5Tg(AMH-cre)1Flor/Plekha5+
involves: 129X1/SvJ * C57BL/6 * SJL 		abnormal Leydig cell morphology J:157337
arrest of spermatogenesis J:157337
decreased testis weight J:157337
normal growth/size/body region phenotype J:157337
Leydig cell hypertrophy J:157337
male infertility J:157337
small seminiferous tubules J:157337
Artm1Jdz/Y
Plekha5Tg(AMH-cre)1Flor/Plekha5+
Tg(Abpa-cre)1Cmal/0
involves: 129X1/SvJ * C57BL/6 * DBA/2 * SJL 		decreased testis weight J:157337
Artm1Jdz/Y
Plekha5Tg(AMH-cre)1Flor/Plekha5Tg(AMH-cre)1Flor
involves: 129X1/SvJ * C57BL/6 * SJL 		arrest of spermatogenesis J:157337
decreased testis weight J:157337
small seminiferous tubules J:157337
Artm1Jdz/Y
Tg(Abpa-cre)1Cmal/0
involves: 129X1/SvJ * C57BL/6 * DBA/2 		abnormal Leydig cell morphology J:157337
abnormal spermatogenesis J:157337
decreased testis weight J:157337
normal growth/size/body region phenotype J:157337
Leydig cell hypertrophy J:157337
male infertility J:157337
small seminiferous tubules J:157337
Artm1Jdz/Y
Tg(Abpa-cre)1Cmal/Tg(Abpa-cre)1Cmal
involves: 129X1/SvJ * C57BL/6 * DBA/2 		abnormal testis morphology J:157337
arrest of spermatogenesis J:157337
decreased testis weight J:157337
small seminiferous tubules J:157337
Artm1Jdz/Y
Tg(CMV-cre)1Cgn/0
involves: 129X1/SvJ * BALB/cJ 		decreased testis weight J:157337
Artm1Jdz/Y
Tg(Pbsn-cre)20Fwan/?
involves: 129X1/SvJ * C57BL/6 * FVB/NCrl 		abnormal prostate gland anterior lobe morphology J:122327
abnormal prostate gland epithelium morphology J:122327
abnormal prostate gland morphology J:122327
abnormal seminal vesicle epithelium morphology J:122327
decreased epididymis weight J:122327
decreased prostate gland weight J:122327
decreased seminal vesicle weight J:122327
normal growth/size/body region phenotype J:122327
small prostate gland J:122327
small prostate gland anterior lobe J:122327
small prostate gland ventral lobe J:122327
Artm1Jdz/Y
Tg(Pbsn-cre)20Fwan/?
involves: 129X1/SvJ * C57BL/6J * FVB/NCrl 		abnormal cauda epididymis morphology J:137429
abnormal copulatory plug biosynthesis J:137429
abnormal corpus epididymis morphology J:137429
abnormal seminal vesicle epithelium morphology J:137429
abnormal seminal vesicle morphology J:137429
abnormal seminal vesicle muscle layer morphology J:137429
abnormal sperm flagellum morphology J:137429
abnormal sperm number J:137429
coiled sperm flagellum J:137429
decreased copulatory plug deposition J:137429
decreased litter size J:137429
decreased seminal vesicle weight J:137429
hairpin sperm flagellum J:137429
impaired fertilization J:137429
kinked sperm flagellum J:137429
premature acrosome reaction J:137429
reduced male fertility J:137429
normal reproductive system phenotype J:137429
small seminal vesicle J:137429
Artm1Rax/Y
involves: 129S/SvEv * C57BL/6J 		no abnormal phenotype detected J:147485
Artm1Rax/Artm1Rax
involves: 129S/SvEv * C57BL/6J 		no abnormal phenotype detected J:147485
Artm1Reb/Y
involves: 129S4/SvJaeSor 		abnormal seminiferous tubule morphology J:90393
abnormal testis morphology J:90393
normal behavior/neurological phenotype J:90393
decreased seminal vesicle weight J:90393
decreased testis weight J:90393
increased circulating follicle stimulating hormone level J:90393
increased circulating luteinizing hormone level J:90393
increased circulating pituitary hormone level J:90393
increased circulating testosterone level J:90393
oligozoospermia J:90393
Artm1Reb/Y
Tg(Amh-cre)8815Reb/?
involves: 129S4/SvJaeSor * FVB/N 		abnormal seminiferous tubule morphology J:90393
abnormal Sertoli cell barrier function J:210656
abnormal testis morphology J:90393
azoospermia J:90393
decreased seminal vesicle weight J:90393
decreased testis weight J:90393
increased circulating follicle stimulating hormone level J:90393
increased circulating luteinizing hormone level J:90393
increased circulating pituitary hormone level J:90393
increased circulating testosterone level J:90393
Artm1Ska/Y
Tg(CMV-cre)1Ipc/?
involves: C57BL/6 * CBA 		abnormal body weight J:85484
abnormal heart left ventricle morphology J:101049
abnormal myocardial fiber morphology J:101049
abnormal penis morphology J:85484
abnormal reproductive system physiology J:85484
absent epididymis J:85484
absent prostate gland J:85484
absent seminal vesicle J:85484
absent vas deferens J:85484
arrest of spermatogenesis J:85484
blind vagina J:85484
cardiac interstitial fibrosis J:101049
cryptorchism J:85484
decreased heart left ventricle muscle contractility J:101049
decreased heart left ventricle wall thickness J:101049
decreased heart weight J:101049
decreased myocardial fiber size J:101049
increased white adipose tissue amount J:85484
obese J:85484
postnatal growth retardation J:85484
secondary sex reversal J:85484
small heart J:101049
testis degeneration J:85484
Artm1Verh/Y
involves: 129S1/Sv * 129X1/SvJ 		normal reproductive system phenotype J:88169
Artm1Verh/Y
Plekha5Tg(AMH-cre)1Flor/Plekha5+
involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 		abnormal Leydig cell morphology J:100799
abnormal spermatid morphology J:88169
abnormal spermatocyte morphology J:88169
arrest of male meiosis J:88169
arrest of spermatogenesis J:88169
azoospermia J:88169
decreased epididymis weight J:88169
decreased Leydig cell number J:100799
decreased male germ cell number J:88169
decreased testis weight J:88169, J:100799
normal growth/size/body region phenotype J:88169
increased circulating follicle stimulating hormone level J:88169
increased male germ cell apoptosis J:88169
small seminiferous tubules J:88169
small testis J:88169
Artm1Verh/Y
Rnase10tm1(cre)Hht/Rnase10+
involves: 129S7/SvEvBrd * C57BL/6 		abnormal caput epididymis morphology J:173897
abnormal epididymis epithelium morphology J:173897
abnormal epididymis morphology J:173897
abnormal male genitalia morphology J:173897
abnormal male reproductive system physiology J:173897
abnormal testis morphology J:173897
enlarged testis J:173897
epididymis epithelium degeneration J:173897
male infertility J:173897
seminiferous tubule degeneration J:173897
testicular atrophy J:173897
testis inflammation J:173897
Artm1Verh/Y
Tg(Fabp4-cre)1Rev/0
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 		abnormal adipose tissue amount J:196857
decreased gonadal fat pad weight J:196857
decreased susceptibility to weight gain J:196857
hyperglycemia J:196857
impaired glucose tolerance J:196857
increased brown adipose tissue amount J:196857
increased circulating insulin level J:196857
increased circulating triglyceride level J:196857
increased interscapular fat pad weight J:196857
increased mesenteric fat pad weight J:196857
increased omental fat pad weight J:196857
insulin resistance J:196857
Artm2.1Reb/Ar+
Tg(Amh-cre)8815Reb/?
129S(FVB)-Artm2.1Reb 		abnormal Sertoli cell barrier function J:210656
abnormal Sertoli cell barrier morphology J:210656
Artm2Ska/Artm2Ska
Pax7tm2.1(cre/ERT2)Fan/Pax7+
involves: 129S1/Sv * 129X1/SvJ * C57BL/6NCrlj * CBA/JNCrl 		normal muscle phenotype J:316008
Artm2Ska/Artm2Ska
Tg(ACTA1-cre)79Jme/0
involves: C57BL/6J * C57BL/6NCrlj * CBA/JNCrlj * SJL 		decreased grip strength J:316008
Artm2Ska/Y
Gli1tm3(cre/ERT2)Alj/Gli1+
involves: 129S6/SvEvTac * C57BL/6 * CBA 		abnormal external male genitalia morphology J:148515
abnormal foreskin morphology J:148515
abnormal reproductive system development J:148515
Artm2Ska/Y
Shhtm2(cre/ERT2)Cjt/Shh+
involves: 129S6/SvEvTac * C57BL/6 * CBA 		normal reproductive system phenotype J:148515
Artm2Ska/Y
Tg(KRT5-cre)1Tak/0
involves: C3H * C57BL/6 * CBA 		normal reproductive system phenotype J:148515
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory